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FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…

{\bf Purpose:} This study evaluates a compact biocompatible Seven-probe Scintillator Detector (7SD) for monitoring HDR-BT treatment sequences across a range of dwell times and source-probe spacings representative of most HDR-BT techniques.…

In particle physics experiments, pulse shape discrimination (PSD) is a powerful tool for eliminating the major background from signals. However, the analysis methods have been a bottleneck to improving PSD performance. In this study, two…

Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…

Anatomical motion and deformation pose challenges to the understanding of the delivered dose distribution during radiotherapy treatments. Hence, deformable image registration (DIR) algorithms are increasingly used to map contours and dose…

Purpose: Ultra-fast scintillation imaging has been shown to provide a unique tool for spatio-temporal dosimetry of conventional cyclotron and synchrocyclotron pencil beam scanning (PBS) deliveries, indicating the potential use for…

This report presents the design, characterization, and application of a high-sensitivity optical detection system based on plastic scintillators coupled to Multi-Pixel Photon Counters (MPPCs). The primary objective was to evaluate the…

Pulse shape discrimination (PSD) is one of the most distinctive features of liquid scintillators. Since the introduction of the scintillation techniques in the field of particle detection, many studies have been carried out to characterize…

Purpose: Many planning methods for high dose rate (HDR) brachytherapy treatment planning require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose…

Purpose: To provide a fast computational method, based on the proximal graph solver (POGS) - a convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating…

Purpose: A diode EDGE Detector with a newly designed electrometer has been characterized for use in an UHDR electron beam and demonstrated appropriateness for UHDR FLASH radiotherapy dosimetry. Methods: Dose linearity, mean dose rate, and…

The following thesis presents research which constitutes the first steps towards the construction of a novel SiFi-CC detector intended for real-time monitoring of proton therapy. The detector construction will be based on inorganic…

We report on the results of the positional-dependent pulse shape discrimination (PSD) parameter observed within a monolithic CLLB scintillation crystal. CLLB, a relatively novel inorganic scintillation crystal, is capable of PSD between…

SBND is the near detector of the Short-Baseline Neutrino program at Fermilab. Its location near to the Booster Neutrino Beam source and relatively large mass will allow the study of neutrino interactions on argon with unprecedented…

With the development of high-speed readout electronics, the digital pulse shape discrimination (PSD) methods have attracted the attention of more researchers, especially in the field of high energy physics and neutron detection. How to…

As small radiation fields play an ever-increasing role in radiation therapy, accurate dosimetry of these fields becomes critical to ensure high quality dose calculation and treatment optimization. The PRB-0002, a new plastic scintillation…

In this work, the standard CsI(Tl) scintillator was used to determine the characteristics of a proton beam. By irradiating the scintillator with a proton beam, it was able to subsequently measure the emitted light using a spectrometer. This…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

In many physical experiments and applications with photomultiplier tubes (PMTs), high-speed pulse digitalization is used extensively. The current pulse from a PMT has a rising time of several to a hundred nanoseconds. The current pulse…

Current clinical PET systems utilize detectors where the scintillator typically contains single elements of 3 - 6 mm width and about 20 mm height. While providing good TOF performance, this design limits the spatial resolution and causes…