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Multimorbidities are associated with significant burden on the healthcare system and the lack of accurate and pertinent statistical exploratory techniques have often limited their analysis. Here we employ exploratory hierarchal…

组织与器官 · 定量生物学 2018-08-23 Rasika Karkare

Clustering multimorbidity has been a global research priority in recent years. Existing studies usually identify these clusters using one of several popular clustering methods and then explore various characteristics of these clusters,…

应用统计 · 统计学 2025-05-06 Sohan Seth , Nazir Lone , Niels Peek , Bruce Guthrie

This study investigates long-term cardiovascular complications in COVID-19 patients using advanced clustering techniques. The objective was to analyse ECG parameters, demographic data, comorbidities, and hospitalization details to identify…

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

机器学习 · 计算机科学 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

机器学习 · 计算机科学 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Multimorbidity, or the presence of several medical conditions in the same individual, has been increasing in the population, both in absolute and relative terms. However, multimorbidity remains poorly understood, and the evidence from…

Multimorbidity, the co-occurrence of two or more chronic diseases such as diabetes, obesity or cardiovascular diseases in one patient, is a frequent phenomenon. To make care more efficient, it is of relevance to understand how different…

医学物理 · 物理学 2019-08-05 Nils Haug , Stefan Thurner , Alexandra Kautzky-Willer , Michael Gyimesi , Peter Klimek

There are many clustering methods, such as hierarchical clustering method. Most of the approaches to the clustering of variables encountered in the literature are of hierarchical type. The great majority of hierarchical approaches to the…

数据库 · 计算机科学 2011-01-25 Rahmat Widia Sembiring , Jasni Mohamad Zain , Abdullah Embong

In this paper we present a method for the unsupervised clustering of high-dimensional binary data, with a special focus on electronic healthcare records. We present a robust and efficient heuristic to face this problem using tensor…

机器学习 · 统计学 2017-08-31 Matteo Ruffini , Ricard Gavaldà , Esther Limón

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

机器学习 · 计算机科学 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

医学物理 · 物理学 2020-06-17 Changhee Lee , Mihaela van der Schaar

Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…

统计方法学 · 统计学 2016-09-23 Sheila Gaynor , Eric Bair

The applicability of agglomerative clustering, for inferring both hierarchical and flat clustering, is limited by its scalability. Existing scalable hierarchical clustering methods sacrifice quality for speed and often lead to over-merging…

This paper introduces a new unsupervised method for the clustering of physiological data into health states based on their similarity. We propose an iterative hierarchical clustering approach that combines health states according to a…

信号处理 · 电气工程与系统科学 2018-03-28 Fabian Schrumpf , Gerold Bausch , Matthias Sturm , Mirco Fuchs

Understanding treatment effect heterogeneity is vital for scientific and policy research. However, identifying and evaluating heterogeneous treatment effects pose significant challenges due to the typically unknown subgroup structure.…

统计方法学 · 统计学 2024-11-05 Kwangho Kim , Jisu Kim , Larry A. Wasserman , Edward H. Kennedy

Multiple outcomes, both continuous and discrete, are routinely gathered on subjects in longitudinal studies and during routine clinical follow-up in general. To motivate our work, we consider a longitudinal study on patients with primary…

应用统计 · 统计学 2013-04-17 Arnošt Komárek , Lenka Komárková

One of the most widely used techniques for data clustering is agglomerative clustering. Such algorithms have been long used across many different fields ranging from computational biology to social sciences to computer vision in part…

机器学习 · 计算机科学 2014-07-15 Maria-Florina Balcan , Yingyu Liang , Pramod Gupta

Background: Most people with any long-term condition have multiple long-term conditions, but our understanding of how conditions cluster is limited. Many clustering studies identify clusters in the whole population, but the clusters that…

应用统计 · 统计学 2025-05-19 Anirban Chakraborty , Bruce Guthrie , Sohan Seth

Agglomerative hierarchical clustering is one of the most widely used approaches for exploring how observations in a dataset relate to each other. However, its greedy nature makes it highly sensitive to small perturbations in the data, often…

统计方法学 · 统计学 2026-03-17 Di Wu , Jacob Bien , Snigdha Panigrahi

We consider the problem of model-based clustering in the presence of many correlated, mixed continuous and discrete variables, some of which may have missing values. Discrete variables are treated with a latent continuous variable approach…

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