相关论文: Fast Characterization of Segmental Duplications in…
A common problem in bioinformatics is related to identifying gene regulatory regions marked by relatively high frequencies of motifs, or deoxyribonucleic acid sequences that often code for transcription and enhancer proteins. Predicting…
Semi-supervised 3D medical image segmentation aims to achieve accurate segmentation using few labelled data and numerous unlabelled data. The main challenge in the design of semi-supervised learning methods consists in the effective use of…
This paper provides a novel framework for single-domain generalized object detection (i.e., Single-DGOD), where we are interested in learning and maintaining the semantic structures of self-augmented compound cross-domain samples to enhance…
Defects in semiconductor crystals can have significant detrimental effects on their performance as radiation detectors. Defects cause charge trapping and recombination, leading to lower signal amplitudes and poor energy resolution. We have…
Complexity metrics and machine learning (ML) models have been utilized to analyze the lengths of segmental genomic entities like: exons, introns, intergenic and repeat/unique DNA sequences, in each of the 22 human chromosomes. The purpose…
Biological sequence analysis relies on the ability to denoise the imprecise output of sequencing platforms. We consider a common setting where a short sequence is read out repeatedly using a high-throughput long-read platform to generate…
Changes in the number of copies of certain parts of the genome, known as copy number alterations (CNAs), due to somatic mutation processes are a hallmark of many cancers. This genomic complexity is known to be associated with poorer…
In this research, we introduce a unified end-to-end Automated Defect Classification-Detection-Segmentation (ADCDS) framework for classifying, detecting, and segmenting multiple instances of semiconductor defects for advanced nodes. This…
Local feature matching remains a fundamental challenge in computer vision. Recent Area to Point Matching (A2PM) methods have improved matching accuracy. However, existing research based on this framework relies on inefficient pixel-level…
In this work, we investigate a challenging problem, which has been considered to be an important criterion in designing codewords for DNA computing purposes, namely secondary structure avoidance in single-stranded DNA molecules. In short,…
Medical image segmentation is fundamental for computer-aided diagnostics, providing accurate delineation of anatomical structures and pathological regions. While common metrics such as Accuracy, DSC, IoU, and HD primarily quantify spatial…
Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…
Recently, speculative decoding (SD) has emerged as a promising technique to accelerate LLM inference by employing a small draft model to propose draft tokens in advance, and validating them in parallel with the large target model. However,…
In this paper, we propose an easily trained yet powerful representation learning approach with performance highly competitive to deep neural networks in a digital pathology image segmentation task. The method, called sparse coding driven…
Locally Decodable Codes (LDCs) are error-correcting codes $C:\Sigma^n\rightarrow \Sigma^m$ with super-fast decoding algorithms. They are important mathematical objects in many areas of theoretical computer science, yet the best…
Time Series Classification (TSC) is essential in fields like medicine, environmental science, and finance, enabling tasks such as disease diagnosis, anomaly detection, and stock price analysis. While machine learning models like Recurrent…
Sequence alignment is a cornerstone technique in computational biology for assessing similarities and differences among biological sequences. A key variant, sequence-to-graph alignment, plays a crucial role in effectively capturing genetic…
The Gene or DNA sequence in every cell does not control genetic properties on its own; Rather, this is done through translation of DNA into protein and subsequent formation of a certain 3D structure. The biological function of a protein is…
Code clones can detrimentally impact software maintenance and manually detecting them in very large codebases is impractical. Additionally, automated approaches find detection of Type 3 and Type 4 (inexact) clones very challenging. While…
With the advent of Next-Generation (NG) sequencing, it has become possible to sequence an entire genome quickly and inexpensively. However, in some experiments one only needs to extract and assembly a portion of the sequence reads, for…