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Determination of the minimum inhibitory concentration (MIC) of a drug that prevents microbial growth is an important step for managing patients with infections. In this paper we present a novel probabilistic approach that accurately…

This study examines the application of Bayesian approach in the context of clinical trials, emphasizing their increasing importance in contemporary biomedical research. While conventional frequentist approach provides a foundational basis…

统计方法学 · 统计学 2026-01-16 Paramahansa Pramanik , Arnab Kumar Maity , Anjan Mandal , Haley Kate Robinson

Medical imaging often contains critical fine-grained features, such as tumors or hemorrhages, crucial for diagnosis yet potentially too subtle for detection with conventional methods. In this paper, we introduce \textit{DIA}, dissolving is…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Jian Shi , Pengyi Zhang , Ni Zhang , Hakim Ghazzai , Peter Wonka

In multivariate spline regression, the number and locations of knots influence the performance and interpretability significantly. However, due to non-differentiability and varying dimensions, there is no desirable frequentist method to…

统计方法学 · 统计学 2024-05-24 Junhui He , Ying Yang , Jian Kang

Computational cardiovascular models are promising tools for clinical decision support, particularly in complex conditions, such as intraoperative hypotension (IOH). IOH arises from different mechanisms, making treatment selection…

医学物理 · 物理学 2025-09-19 Jan-Niklas Thiel , Marko Zlicar , Ulrich Steinseifer , Borut Kirn , Michael Neidlin

Statistical agencies and other institutions collect data under the promise to protect the confidentiality of respondents. When releasing microdata samples, the risk that records can be identified must be assessed. To this aim, a widely…

应用统计 · 统计学 2015-06-03 Cinzia Carota , Maurizio Filippone , Roberto Leombruni , Silvia Polettini

We present a method for identification of models with good predictive performances in the family of Bayesian log-linear mixed models with Dirichlet process random effects. Such a problem arises in many different applications; here we…

统计方法学 · 统计学 2018-01-17 Cinzia Carota , Maurizio Filippone , Silvia Polettini

Bayesian models based on the Dirichlet process and other stick-breaking priors have been proposed as core ingredients for clustering, topic modeling, and other unsupervised learning tasks. Prior specification is, however, relatively…

统计方法学 · 统计学 2021-10-27 Ryan Giordano , Runjing Liu , Michael I. Jordan , Tamara Broderick

Bayesian models based on the Dirichlet process and other stick-breaking priors have been proposed as core ingredients for clustering, topic modeling, and other unsupervised learning tasks. However, due to the flexibility of these models,…

统计方法学 · 统计学 2022-01-27 Ryan Giordano , Runjing Liu , Michael I. Jordan , Tamara Broderick

We consider the problem of choosing between parametric models for a discrete observable, taking a Bayesian approach in which the within-model prior distributions are allowed to be improper. In order to avoid the ambiguity in the marginal…

统计理论 · 数学 2020-04-28 A. Philip Dawid , Monica Musio , Silvia Columbu

We provide a mathematical formulation and develop a computational framework for identifying multiple strains of microorganisms from mixed samples of DNA. Our method is applicable in public health domains where efficient identification of…

Detecting associations between microbial compositions and sample characteristics is one of the most important tasks in microbiome studies. Most of the existing methods apply univariate models to single microbial species separately, with…

统计方法学 · 统计学 2021-03-18 Boyu Ren , Sergio Bacallado , Stefano Favaro , Tommi Vatanen , Curtis Huttenhower , Lorenzo Trippa

In recent years dynamical modelling has been provided with a range of breakthrough methods to perform exact Bayesian inference. However it is often computationally unfeasible to apply exact statistical methodologies in the context of large…

统计计算 · 统计学 2014-12-24 Umberto Picchini , Julie Lyng Forman

We develop a Bayesian inference method for diffusions observed discretely and with noise, which is free of discretisation bias. Unlike existing unbiased inference methods, our method does not rely on exact simulation techniques. Instead,…

统计方法学 · 统计学 2021-03-10 Neil K. Chada , Jordan Franks , Ajay Jasra , Kody J. H. Law , Matti Vihola

We propose a Bayesian approach for both medical inquiry and disease inference, the two major phases in differential diagnosis. Unlike previous work that simulates data from given probabilities and uses ML algorithms on them, we directly use…

人工智能 · 计算机科学 2021-10-26 Hong Guan , Chitta Baral

We consider a nonparametric Bayesian approach to estimation and testing for a multivariate monotone density. Instead of following the conventional Bayesian route of putting a prior distribution complying with the monotonicity restriction,…

统计理论 · 数学 2023-06-09 Kang Wang , Subhashis Ghosal

Materials with heterogeneous structures exhibit complex physical processes such as delamination, cracks, and plasticity, which require micromechanical parameters for understanding. However, identifying these parameters is challenging due to…

偏微分方程分析 · 数学 2023-06-26 Liya Gaynutdinova , Ondřej Rokoš , Jan Havelka , Ivana Pultarová , Jan Zeman

Mixture models are well-known for their versatility, and the Bayesian paradigm is a suitable platform for mixture analysis, particularly when the number of components is unknown. Bhattacharya (2008) introduced a mixture model based on the…

统计理论 · 数学 2018-11-19 Sabyasachi Mukhopadhyay , Sourabh Bhattacharya

We provide a flexible framework for selecting among a class of additive partial linear models that allows both linear and nonlinear additive components. In practice, it is challenging to determine which additive components should be…

统计方法学 · 统计学 2021-09-20 Seonghyun Jeong , Taeyoung Park , David A. van Dyk

In the problem of selecting variables in a multivariate linear regression model, we derive new Bayesian information criteria based on a prior mixing a smooth distribution and a delta distribution. Each of them can be interpreted as a fusion…

统计理论 · 数学 2022-09-29 Haruki Kono , Tatsuya Kubokawa
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