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Understanding covariate-varying interdependencies among features is of great interest in various applications. Motivated by microbiome studies where microbial abundances and interactions vary with environmental factors, we develop a…

统计方法学 · 统计学 2026-03-16 Shuangjie Zhang , Michael L. Patnode , Juhee Lee

Evaluating spatial patterns in data is an integral task across various domains, including geostatistics, astronomy, and spatial tissue biology. The analysis of transcriptomics data in particular relies on methods for detecting…

统计方法学 · 统计学 2025-05-26 Katharina Limbeck , Bastian Rieck

We present new theoretical and empirical results on the probability distributions of species persistence times in natural ecosystems. Persistence times, defined as the timespans occurring between species' colonization and local extinction…

种群与进化 · 定量生物学 2012-03-21 S. Suweis , E. Bertuzzo , L. Mari , I. Rodriguez-Iturbe , A. Maritan , A. Rinaldo

Lyme disease is an infectious disease that is caused by a bacterium called Borrelia burgdorferi sensu stricto. In the United States, Lyme disease is one of the most common infectious diseases. The major endemic areas of the disease are New…

应用统计 · 统计学 2018-09-19 Yimeng Xie , Li Xu , Jie Li , Xinwei Deng , Yili Hong , Korine Kolivras , David N. Gaines

We propose a series-based nonparametric specification test for a regression function when data are spatially dependent, the `space' being of a general economic or social nature. Dependence can be parametric, parametric with increasing…

计量经济学 · 经济学 2022-08-30 Abhimanyu Gupta , Xi Qu

Its conceptual appeal and effectiveness has made latent factor modeling an indispensable tool for multivariate analysis. Despite its popularity across many fields, there are outstanding methodological challenges that have hampered practical…

统计方法学 · 统计学 2018-12-12 Kenichiro McAlinn , Veronika Rockova , Enakshi Saha

In recent years, conditional copulas, that allow dependence between variables to vary according to the values of one or more covariates, have attracted increasing attention. In high dimension, vine copulas offer greater flexibility compared…

统计方法学 · 统计学 2021-09-24 Rosario Barone , Luciana Dalla Valle

Synthetic microbiomes offer new possibilities for modulating microbiota, to address the barriers in multidtug resistance (MDR) research. We present a Bayesian optimization approach to enable efficient searching over the space of synthetic…

定量方法 · 定量生物学 2024-05-02 Nisha Pillai , Bindu Nanduri , Michael J Rothrock , Zhiqian Chen , Mahalingam Ramkumar

Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…

应用统计 · 统计学 2023-05-16 Arhit Chakrabarti , Yang Ni , Bani K. Mallick

Factor analysis has been extensively used to reveal the dependence structures among multivariate variables, offering valuable insight in various fields. However, it cannot incorporate the spatial heterogeneity that is typically present in…

统计方法学 · 统计学 2024-11-14 Yanxiu Jin , Tomoya Wakayama , Renhe Jiang , Shonosuke Sugasawa

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple…

种群与进化 · 定量生物学 2018-02-15 Michael Manhart , Bharat V. Adkar , Eugene I. Shakhnovich

We present a novel Bayesian spatial disaggregation model for count data, providing fast and flexible inference at high resolution. First, it incorporates non-linear covariate effects using penalized splines, a flexible approach that is not…

统计方法学 · 统计学 2026-04-13 Sara Rutten , Thomas Neyens , Elisa Duarte , Christel Faes

In this article a flexible Bayesian non-parametric model is proposed for non-homogeneous hidden Markov models. The model is developed through the amalgamation of the ideas of hidden Markov models and predictor dependent stick-breaking…

统计方法学 · 统计学 2012-05-10 Abhra Sarkar , Anindya Bhadra , Bani K. Mallick

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

种群与进化 · 定量生物学 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

应用统计 · 统计学 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

We study the problem of incorporating covariates in a compound decision setup. It is desired to estimate the means of $n$ response variables, which are independent and normally distributed, and each is accompanied by a vector of covariates.…

统计理论 · 数学 2010-12-08 N. Cohen , E. Greenshtein , Y. Ritov

The decreasing cost and improved sensor and monitoring system technology (e.g. fiber optics and strain gauges) have led to more measurements in close proximity to each other. When using such spatially dense measurement data in Bayesian…

统计方法学 · 统计学 2023-08-21 Ioannis Koune , Arpad Rozsas , Arthur Slobbe , Alice Cicirello

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

物理与社会 · 物理学 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Several studies on heritability in twins aim at understanding the different contribution of environmental and genetic factors to specific traits. Considering the National Merit Twin Study, our purpose is to correctly analyse the influence…

统计方法学 · 统计学 2017-07-04 Luciana Dalla Valle , Fabrizio Leisen , Luca Rossini

It is now practically the norm for data to be very high dimensional in areas such as genetics, machine vision, image analysis and many others. When analyzing such data, parametric models are often too inflexible while nonparametric…

统计方法学 · 统计学 2011-05-31 Abhishek Bhattacharya , Garritt Page , David Dunson
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