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Probabilistic finite mixture models are widely used for unsupervised clustering. These models can often be improved by adapting them to the topology of the data. For instance, in order to classify spatially adjacent data points similarly,…

计算机视觉与模式识别 · 计算机科学 2022-02-09 Jonathan Vacher , Claire Launay , Ruben Coen-Cagli

Bayesian nonparametric mixture models are common for modeling complex data. While these models are well-suited for density estimation, recent results proved posterior inconsistency of the number of clusters when the true number of…

统计理论 · 数学 2024-05-31 Louise Alamichel , Daria Bystrova , Julyan Arbel , Guillaume Kon Kam King

Problem Definition. Increasing costs of healthcare highlight the importance of effective disease prevention. However, decision models for allocating preventive care are lacking. Methodology/Results. In this paper, we develop a data-driven…

机器学习 · 计算机科学 2023-08-15 Mathias Kraus , Stefan Feuerriegel , Maytal Saar-Tsechansky

Comorbid diseases co-occur and progress via complex temporal patterns that vary among individuals. In electronic health records we can observe the different diseases a patient has, but can only infer the temporal relationship between each…

机器学习 · 计算机科学 2020-01-22 Zhaozhi Qian , Ahmed M. Alaa , Alexis Bellot , Jem Rashbass , Mihaela van der Schaar

Objective: Electronic health records (EHR) are widely available to complement administrative data-based disease surveillance and healthcare performance evaluation. Defining conditions from EHR is labour-intensive and requires extensive…

计算与语言 · 计算机科学 2025-04-09 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Elliot A. Martin , Kiarash Riazi , Hude Quan , Na Li

Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data…

人工智能 · 计算机科学 2012-08-20 Casey Bennett , Tom Doub , Rebecca Selove

The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

定量方法 · 定量生物学 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

Motivation: Unanticipated drug-drug interactions (DDIs) pose significant risks in polypharmacy, emphasizing the need for predictive methods. Recent advancements in computational techniques aim to address this challenge. Methods: We…

Bayesian neural networks (BNNs) can account for both aleatoric and epistemic uncertainty. However, in BNNs the priors are often specified over the weights which rarely reflects true prior knowledge in large and complex neural network…

机器学习 · 计算机科学 2023-01-25 Vishnu Raj , Tianyu Cui , Markus Heinonen , Pekka Marttinen

Medical knowledge extraction methods based on edge computing deploy deep learning models on edge devices to achieve localized entity and relation extraction. This approach avoids transferring substantial sensitive data to cloud data…

计算与语言 · 计算机科学 2024-01-17 Fan Lu , Quan Qi , Huaibin Qin

Predicting potential outcomes of interventions from observational data is crucial for decision-making in medicine, but the task is challenging due to the fundamental problem of causal inference. Existing methods are largely limited to point…

机器学习 · 计算机科学 2024-10-14 Yuchen Ma , Valentyn Melnychuk , Jonas Schweisthal , Stefan Feuerriegel

In many forecasting applications, it is valuable to predict not only the value of a signal at a certain time point in the future, but also the values leading up to that point. This is especially true in clinical applications, where the…

机器学习 · 计算机科学 2019-04-09 Ian Fox , Lynn Ang , Mamta Jaiswal , Rodica Pop-Busui , Jenna Wiens

Type 2 Diabetes Mellitus (T2DM) remains a global health challenge, underscoring the need for early and accurate risk prediction. This study presents ECG-DiaNet, a multimodal deep learning model that integrates electrocardiogram (ECG)…

机器学习 · 计算机科学 2025-04-09 Farida Mohsen , Zubair Shah

Evidential Deep Learning (EDL) is a popular framework for uncertainty-aware classification that models predictive uncertainty via Dirichlet distributions parameterized by neural networks. Despite its popularity, its theoretical foundations…

机器学习 · 统计学 2026-02-03 Pietro Carlotti , Nevena Gligić , Arya Farahi

With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous…

应用统计 · 统计学 2018-01-29 Maryan Morel , Emmanuel Bacry , Stéphane Gaïffas , Agathe Guilloux , Fanny Leroy

We develop a sequential low-complexity inference procedure for Dirichlet process mixtures of Gaussians for online clustering and parameter estimation when the number of clusters are unknown a-priori. We present an easily computable, closed…

机器学习 · 统计学 2015-09-15 Theodoros Tsiligkaridis , Keith W. Forsythe

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

机器学习 · 计算机科学 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Type 2 diabetes mellitus (T2DM) is one of the most common diseases and a leading cause of death. The problem of early diagnosis of T2DM is challenging and necessary to prevent serious complications. This study proposes a novel neural…

机器学习 · 计算机科学 2023-01-20 Tayyab Nasir , Muhammad Kamran Malik

We consider the problem of estimating the average treatment effect (ATE) in a semi-supervised learning setting, where a very small proportion of the entire set of observations are labeled with the true outcome but features predictive of the…

统计方法学 · 统计学 2020-10-27 David Cheng , Ashwin Ananthakrishnan , Tianxi Cai

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

机器学习 · 计算机科学 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo