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Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

统计方法学 · 统计学 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

The modelling of Electronic Health Records (EHRs) has the potential to drive more efficient allocation of healthcare resources, enabling early intervention strategies and advancing personalised healthcare. However, EHRs are challenging to…

机器学习 · 计算机科学 2020-12-08 Joseph Enguehard , Dan Busbridge , Adam Bozson , Claire Woodcock , Nils Y. Hammerla

Patient representation learning based on electronic health records (EHR) is a critical task for disease prediction. This task aims to effectively extract useful information on dynamic features. Although various existing works have achieved…

机器学习 · 计算机科学 2024-01-02 Ziyue Yu , Jiayi Wang , Wuman Luo , Rita Tse , Giovanni Pau

Gaussian process (GP) models provide a powerful tool for prediction but are computationally prohibitive using large data sets. In such scenarios, one has to resort to approximate methods. We derive an approximation based on a composite…

机器学习 · 统计学 2018-02-02 Xiuming Liu , Dave Zachariah , Edith C. H. Ngai

Although Gaussian processes (GPs) with deep kernels have been successfully used for meta-learning in regression tasks, its uncertainty estimation performance can be poor. We propose a meta-learning method for calibrating deep kernel GPs for…

机器学习 · 统计学 2023-12-14 Tomoharu Iwata , Atsutoshi Kumagai

Modeling multivariate time series has long been a subject that has attracted researchers from a diverse range of fields including economics, finance, and traffic. A basic assumption behind multivariate time series forecasting is that its…

机器学习 · 计算机科学 2020-05-26 Zonghan Wu , Shirui Pan , Guodong Long , Jing Jiang , Xiaojun Chang , Chengqi Zhang

Individual treatment effect estimation has gained significant attention in recent data science literature. This work introduces the Double Neural Network (Double-NN) method to address this problem within the framework of extended fiducial…

机器学习 · 统计学 2025-05-06 Sehwan Kim , Faming Liang

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

机器学习 · 计算机科学 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

人工智能 · 计算机科学 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

In this paper, we explore the application of Gaussian Processes (GPs) for predicting mean-reverting time series with an underlying structure, using relatively unexplored functional and augmented data structures. While many conventional…

统计金融 · 定量金融 2024-03-05 Narayan Tondapu

The broad adoption of Electronic Health Records (EHR) has led to vast amounts of data being accumulated on a patient's history, diagnosis, prescriptions, and lab tests. Advances in recommender technologies have the potential to utilize this…

信息检索 · 计算机科学 2020-09-01 Suman Bhoi , Lee Mong Li , Wynne Hsu

Access to electronic health record (EHR) data has motivated computational advances in medical research. However, various concerns, particularly over privacy, can limit access to and collaborative use of EHR data. Sharing synthetic EHR data…

机器学习 · 计算机科学 2018-01-15 Edward Choi , Siddharth Biswal , Bradley Malin , Jon Duke , Walter F. Stewart , Jimeng Sun

Gaussian processes (GPs) are powerful and widely used probabilistic regression models, but their effectiveness in practice is often limited by the choice of kernel function. This kernel function is typically handcrafted from a small set of…

机器学习 · 计算机科学 2026-02-13 Jihao Andreas Lin , Sebastian Ament , Louis C. Tiao , David Eriksson , Maximilian Balandat , Eytan Bakshy

This study proposes a novel, integrative framework for patient-centered data science in the digital health era. We developed a multidimensional model that combines traditional clinical data with patient-reported outcomes, social…

机器学习 · 计算机科学 2024-08-07 Mohsen Amoei , Dan Poenaru

Deep learning models have demonstrated superior performance in various healthcare applications. However, the major limitation of these deep models is usually the lack of high-quality training data due to the private and sensitive nature of…

计算与语言 · 计算机科学 2022-11-15 Qiuhao Lu , Dejing Dou , Thien Huu Nguyen

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

机器学习 · 计算机科学 2025-09-01 Xiaoyang Wang , Christopher C. Yang

The development of statistical approaches for the joint modelling of the temporal changes of imaging, biochemical, and clinical biomarkers is of paramount importance for improving the understanding of neurodegenerative disorders, and for…

应用统计 · 统计学 2018-02-16 Marco Lorenzi , Maurizio Filippone , Daniel C. Alexander , Sebastien Ourselin

Electronic health records (EHR) data provide a cost and time-effective opportunity to conduct cohort studies of the effects of multiple time-point interventions in the diverse patient population found in real-world clinical settings.…

Multi-model ensemble analysis integrates information from multiple climate models into a unified projection. However, existing integration approaches based on model averaging can dilute fine-scale spatial information and incur bias from…

应用统计 · 统计学 2023-04-12 Trevor Harris , Bo Li , Ryan Sriver

Multi-task learning models using Gaussian processes (GP) have been developed and successfully applied in various applications. The main difficulty with this approach is the computational cost of inference using the union of examples from…

机器学习 · 计算机科学 2012-11-29 Yuyang Wang , Roni Khardon