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Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

机器学习 · 计算机科学 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

计算机视觉与模式识别 · 计算机科学 2022-02-18 Robin Elizabeth Yancey

Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…

计算机视觉与模式识别 · 计算机科学 2019-06-11 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

Federated learning and its application to medical image segmentation have recently become a popular research topic. This training paradigm suffers from statistical heterogeneity between participating institutions' local datasets, incurring…

图像与视频处理 · 电气工程与系统科学 2023-10-19 Matthis Manthe , Stefan Duffner , Carole Lartizien

Unsupervised patient stratification is essential for disease subtype discovery, yet, despite growing evidence of molecular heterogeneity of non-oncological diseases, popular methods are benchmarked primarily using cancers with mutually…

Multi-omic data provides multiple views of the same patients. Integrative analysis of multi-omic data is crucial to elucidate the molecular underpinning of disease etiology. However, multi-omic data has the "big p, small N" problem (the…

机器学习 · 计算机科学 2018-09-07 Tianle Ma , Aidong Zhang

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

We propose clustered federated multitask learning to address statistical challenges in non-independent and identically distributed data across clients. Our approach tackles complexities in hierarchical wireless networks by clustering…

网络与互联网体系结构 · 计算机科学 2024-07-15 Moqbel Hamood , Abdullatif Albaseer , Mohamed Abdallah , Ala Al-Fuqaha , Amr Mohamed

Supervised deep learning models often achieve excellent performance within their training distribution but struggle to generalize beyond it. In cancer histopathology, for example, a convolutional neural network (CNN) may classify cancer…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Justin Cheung , Samuel Savine , Calvin Nguyen , Lin Lu , Alhassan S. Yasin

Drug resistance is still a major challenge in cancer therapy. Drug combination is expected to overcome drug resistance. However, the number of possible drug combinations is enormous, and thus it is infeasible to experimentally screen all…

基因组学 · 定量生物学 2018-11-20 Tianyu Zhang , Liwei Zhang , Philip R. O. Payne , Fuhai Li

In this paper, we propose a similarity-aware fusion network (SAFNet) to adaptively fuse 2D images and 3D point clouds for 3D semantic segmentation. Existing fusion-based methods achieve remarkable performances by integrating information…

计算机视觉与模式识别 · 计算机科学 2021-07-20 Linqing Zhao , Jiwen Lu , Jie Zhou

Clinical decision-making in oncology involves multimodal data such as radiology scans, molecular profiling, histopathology slides, and clinical factors. Despite the importance of these modalities individually, no deep learning framework to…

计算机视觉与模式识别 · 计算机科学 2021-07-02 Nathaniel Braman , Jacob W. H. Gordon , Emery T. Goossens , Caleb Willis , Martin C. Stumpe , Jagadish Venkataraman

The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer,…

机器学习 · 统计学 2018-10-30 Siddhant Jain , Jalal Ziauddin , Paul Leonchyk , Joseph Geraci

Federated multi-view clustering offers the potential to develop a global clustering model using data distributed across multiple devices. However, current methods face challenges due to the absence of label information and the paramount…

机器学习 · 计算机科学 2024-06-14 Xueming Yan , Ziqi Wang , Yaochu Jin

Multi-atlas segmentation approach is one of the most widely-used image segmentation techniques in biomedical applications. There are two major challenges in this category of methods, i.e., atlas selection and label fusion. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2018-08-03 Heran Yang , Jian Sun , Huibin Li , Lisheng Wang , Zongben Xu

Multimodal Fusion Learning (MFL), leveraging disparate data from various imaging modalities (e.g., MRI, CT, SPECT), has shown great potential for addressing medical problems such as skin cancer and brain tumor prediction. However, existing…

计算机视觉与模式识别 · 计算机科学 2026-02-18 Joy Dhar , Nayyar Zaidi , Maryam Haghighat

Brain tumor segmentation requires accurate identification of hierarchical regions including whole tumor (WT), tumor core (TC), and enhancing tumor (ET) from multi-sequence magnetic resonance imaging (MRI) images. Due to tumor tissue…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Mingda Zhang , Yuyang Zheng , Ruixiang Tang , Jingru Qiu , Haiyan Ding

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Clustered federated learning (FL) has been shown to produce promising results by grouping clients into clusters. This is especially effective in scenarios where separate groups of clients have significant differences in the distributions of…

机器学习 · 计算机科学 2022-09-22 Saeed Vahidian , Mahdi Morafah , Weijia Wang , Vyacheslav Kungurtsev , Chen Chen , Mubarak Shah , Bill Lin

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu
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