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Mathematical optimization is widely used in various research fields. With a carefully-designed objective function, mathematical optimization can be quite helpful in solving many problems. However, objective functions are usually…

机器学习 · 计算机科学 2019-05-27 Younghan Jeon , Minsik Lee , Jin Young Choi

One of the primary goals of systems neuroscience is to relate the structure of neural circuits to their function, yet patterns of connectivity are difficult to establish when recording from large populations in behaving organisms. Many…

机器学习 · 计算机科学 2020-12-08 Anne Draelos , Eva A. Naumann , John M. Pearson

Neurons convert the external stimuli into action potentials, or spikes, and encode the contained information into the biological nerve system. Despite the complexity of neurons and the synaptic interactions in between, the rate models are…

神经元与认知 · 定量生物学 2021-09-28 Chia-Ying Lin , Ping-Han Chen , Hsiu-Hau Lin , Wen-Min Huang

Research data sets are growing to unprecedented sizes and network modeling is commonly used to extract complex relationships in diverse domains, such as genetic interactions involved in disease, logistics, and social communities. As the…

社会与信息网络 · 计算机科学 2024-05-03 Sharlee Climer , Kenneth Smith , Wei Yang , Lisa de las Fuentes , Victor G. Dávila-Román , C. Charles Gu

The stiffness of the Hodgkin-Huxley (HH) equations during an action potential (spike) limits the use of large time steps. We observe that the neurons can be evolved independently between spikes, $i.e.,$ different neurons can be evolved with…

神经元与认知 · 定量生物学 2021-01-19 Zhong-Qi Kyle Tian , Douglas Zhou

Cellular neural circuit and networks consisting of interconnected neurons and glia are ulti- mately responsible for the information processing associated with information processing in the brain. While there are major efforts aimed at…

神经元与认知 · 定量生物学 2015-05-18 Marius Buibas , Gabriel A. Silva

Spike-sorting techniques attempt to classify a series of noisy electrical waveforms according to the identity of the neurons that generated them. Existing techniques perform this classification ignoring several properties of actual neurons…

定量方法 · 定量生物学 2007-05-23 Christophe Pouzat

Simultaneous recordings from multiple neural units allow us to investigate the activity of very large neural ensembles. To understand how large ensembles of neurons process sensory information, it is necessary to develop suitable…

神经元与认知 · 定量生物学 2013-05-30 Fernando Montani , Elena Phoka , Mariela Portesi , Simon R. Schultz

The circuits comprising superconducting optoelectronic synapses, dendrites, and neurons are described by numerically cumbersome and formally opaque coupled differential equations. Reference 1 showed that a phenomenological model of…

神经与进化计算 · 计算机科学 2024-09-27 Jeffrey M. Shainline , Bryce A. Primavera , Ryan O'Loughlin

We address the questions of identifying pairs of interacting neurons from the observation of their spiking activity. The neuronal network is modeled by a system of interacting point processes with memory of variable length. The influence of…

统计理论 · 数学 2021-06-22 Emilio De Santis , Antonio Galves , Giovanna Nappo , Mauro Piccioni

Traditional neuron models use analog values for information representation and computation, while all-or-nothing spikes are employed in the spiking ones. With a more brain-like processing paradigm, spiking neurons are more promising for…

神经与进化计算 · 计算机科学 2021-02-05 Qiang Yu , Shiming Song , Chenxiang Ma , Linqiang Pan , Kay Chen Tan

Understanding the interaction patterns among simultaneous recordings of spike trains from multiple neuronal units is a key topic in neuroscience. However, an optimal approach of assessing these interactions has not been established, as…

神经元与认知 · 定量生物学 2020-12-17 Gorana Mijatovic , Yuri Antonacci , Tatjana Loncar-Turukalo , Ludovico Minati , Luca Faes

The advent of large scale neural computational platforms has highlighted the lack of algorithms for synthesis of neural structures to perform predefined cognitive tasks. The Neural Engineering Framework offers one such synthesis, but it is…

神经与进化计算 · 计算机科学 2013-04-29 J. Tapson , G. Cohen , S. Afshar , K. Stiefel , Y. Buskila , R. Wang , T. J. Hamilton , A. van Schaik

Recent experimental advances are producing an avalanche of data on both neural connectivity and neural activity. To take full advantage of these two emerging datasets we need a framework that links them, revealing how collective neural…

神经元与认知 · 定量生物学 2020-02-27 Gabriel Koch Ocker , Krešimir Josić , Eric Shea-Brown , Michael A. Buice

We study optimization problems where the objective function is modeled through feedforward neural networks with rectified linear unit (ReLU) activation. Recent literature has explored the use of a single neural network to model either…

机器学习 · 计算机科学 2022-05-11 Keliang Wang , Leonardo Lozano , Carlos Cardonha , David Bergman

We tackle a quantification of synchrony in a large ensemble of interacting neurons from the observation of spiking events. In a simulation study, we efficiently infer the synchrony level in a neuronal population from a point process…

神经元与认知 · 定量生物学 2025-03-25 Arkady Pikovsky , Michael Rosenblum

This paper explores the impact of biologically plausible neuron models on the performance of Spiking Neural Networks (SNNs) for regression tasks. While SNNs are widely recognized for classification tasks, their application to Scientific…

数值分析 · 数学 2024-01-02 Mario De Florio , Adar Kahana , George Em Karniadakis

Much progress has been made in uncovering the computational capabilities of spiking neural networks. However, spiking neurons will always be more expensive to simulate compared to rate neurons because of the inherent disparity in time…

神经元与认知 · 定量生物学 2013-10-31 Michael A. Buice , Carson C. Chow

Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such…

神经元与认知 · 定量生物学 2017-04-18 Henry C. Tuckwell , Ying Zhou , Nicholas J. Penington

This paper models the dynamics of a large set of interacting neurons within the framework of statistical field theory. We use a method initially developed in the context of statistical field theory [44] and later adapted to complex systems…

神经元与认知 · 定量生物学 2022-05-25 Pierre Gosselin , Aïleen Lotz , Marc Wambst