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Unsupervised domain adaptation (UDA) for nuclei instance segmentation is important for digital pathology, as it alleviates the burden of labor-intensive annotation and domain shift across datasets. In this work, we propose a Cycle…

计算机视觉与模式识别 · 计算机科学 2020-05-06 Dongnan Liu , Donghao Zhang , Yang Song , Fan Zhang , Lauren O'Donnell , Heng Huang , Mei Chen , Weidong Cai

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

图像与视频处理 · 电气工程与系统科学 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

图像与视频处理 · 电气工程与系统科学 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

图像与视频处理 · 电气工程与系统科学 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Separating the contributions of individual chromogenic stains in RGB histology whole slide images (WSIs) is essential for stain normalization, quantitative assessment of marker expression, and cell-level readouts in immunohistochemistry…

计算机视觉与模式识别 · 计算机科学 2026-01-19 Mark Eastwood , Thomas McKee , Zedong Hu , Sabine Tejpar , Fayyaz Minhas

Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

计算机视觉与模式识别 · 计算机科学 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto

While challenging, the dense segmentation of histology images is a necessary first step to assess changes in tissue architecture and cellular morphology. Although specific convolutional neural network architectures have been applied with…

计算机视觉与模式识别 · 计算机科学 2018-06-13 Korsuk Sirinukunwattana , Nasullah Khalid Alham , Clare Verrill , Jens Rittscher

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

图像与视频处理 · 电气工程与系统科学 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology help us to…

计算机视觉与模式识别 · 计算机科学 2022-11-01 Yi Cui , Yao Li , Jayson R. Miedema , Sherif Farag , J. S. Marron , Nancy E. Thomas

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

计算机视觉与模式识别 · 计算机科学 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

This paper summarizes the method used in our submission to Task 1 of the International Skin Imaging Collaboration's (ISIC) Skin Lesion Analysis Towards Melanoma Detection challenge held in 2018. We used a fully automated method to…

计算机视觉与模式识别 · 计算机科学 2018-07-16 Joshua Peter Ebenezer , Jagath C. Rajapakse

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

计算机视觉与模式识别 · 计算机科学 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Skin cancer is a global health concern, necessitating early and accurate diagnosis for improved patient outcomes. This study introduces a groundbreaking approach to skin cancer classification, employing the Vision Transformer, a…

图像与视频处理 · 电气工程与系统科学 2024-01-11 Galib Muhammad Shahriar Himel , Md. Masudul Islam , Kh Abdullah Al-Aff , Shams Ibne Karim , Md. Kabir Uddin Sikder

The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won…

定量方法 · 定量生物学 2016-06-21 Dayong Wang , Aditya Khosla , Rishab Gargeya , Humayun Irshad , Andrew H. Beck

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

医学物理 · 物理学 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Annotation scarcity and cross-modality/stain data distribution shifts are two major obstacles hindering the application of deep learning models for nuclei analysis, which holds a broad spectrum of potential applications in digital…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Jianan Fan , Dongnan Liu , Hang Chang , Weidong Cai

The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Xihao Chen , Jingya Yu , Li Chen , Shaoqun Zeng , Xiuli Liu , Shenghua Cheng

The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering…

图像与视频处理 · 电气工程与系统科学 2020-10-06 Kang Li , Lequan Yu , Shujun Wang , Pheng-Ann Heng

This study addresses the essential task of medical image segmentation, which involves the automatic identification and delineation of anatomical structures and pathological regions in medical images. Accurate segmentation is crucial in…

计算机视觉与模式识别 · 计算机科学 2025-07-01 Seyedeh Sahar Taheri Otaghsara , Reza Rahmanzadeh