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Purpose: In this study, we present the creation of an anthropomorphic, head and neck, nuclear medicine phantom and its characterization for the validation of a Monte Carlo, SPECT image based, Iodine-131 RPT dosimetry workflow. Methods: 3D…

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

医学物理 · 物理学 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

医学物理 · 物理学 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

Aim: To improve treatment plan robustness with respect to small shifts in patient position during the VMAT treatment by ensuring a linear ramp-like dose profile in treatment field overlap regions. Background: Craniospinal irradiation (CSI)…

医学物理 · 物理学 2016-03-30 Andrej Strojnik , Ignasi Mendez , Primoz Peterlin

This study evaluates dynamic conformal arc (DCA) therapy as an alternative to volumetric modulated arc therapy (VMAT) for stereotactic body radiation therapy (SBRT) of lung cancer. The rationale for DCA is lower geometric complexity and…

医学物理 · 物理学 2019-05-07 Rasmus Bokrantz , Minna Wedenberg , Peter Sandwall

The first purpose of this paper is to shed some new light on the old question of selecting the number of beams in intensity-modulated radiation therapy (IMRT). The second purpose is to illuminate the related issue of discrete static beam…

医学物理 · 物理学 2015-05-14 Thomas Bortfeld

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

医学物理 · 物理学 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

医学物理 · 物理学 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex multicriteria dose optimization problem is solved for an…

医学物理 · 物理学 2015-05-28 David Craft , Dualta McQuaid , Jeremiah Wala , Wei Chen , Ehsan Salari , Thomas Bortfeld

Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…

定量方法 · 定量生物学 2023-05-15 Mobina Naeemi , Mohamad Reza Esmaeili , Iraj Abedi

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…

医学物理 · 物理学 2021-09-07 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Background and purpose: IMPT faces challenges in lung cancer treatment, like maintaining plan robustness for moving tumors against setup, range errors, and interplay effects. Proton Arc Therapy (PAT) is an alternative to maintain target…

Purpose: To investigate the impact of delivery techniques and planning parameters on interplay effect in lung SBRT. Methods: A dynamic virtual patient model containing normal structures and a tumor with adjustable sizes, locations, and 3D…

Purpose: A promising approach to enable FLASH conformal proton therapy is to passively degrade a single energy layer using a patient-specific range modulator. We propose an innovative method to directly optimize the geometrical…

医学物理 · 物理学 2023-03-16 Sylvain Deffet , Kevin Souris , Edmond Sterpin

The AVATAR system utilizes a radiolucent video display to help relax and immobilize pediatric patients during radiotherapy. This study investigates the use of OLED (Organic Light Emitting Diode) displays, which offer superior image quality…

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Automating the radiotherapy treatment planning process is a technically challenging problem. The majority of automated approaches have focused on customizing and inferring dose volume objectives to used in plan optimization. In this work we…

医学物理 · 物理学 2017-01-04 Chris McIntosh , Thomas G. Purdie

Accurate radiotherapy dose calculation depends on converting CT Hounsfield Units (HU) to relative electron density (RED) using calibration curves. This study compared three different CT-to-RED calibration curves-two derived from physical…

医学物理 · 物理学 2025-05-12 Hossam Donya , Duong Thanh Tai , Islam G. Ali