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In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…

Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…

神经元与认知 · 定量生物学 2026-04-14 Antonios G. Dougalis

Computer aided diagnosis systems can provide non-invasive, low-cost tools to support clinicians. These systems have the potential to assist the diagnosis and monitoring of neurodegenerative disorders, in particular Parkinson's disease (PD).…

计算机视觉与模式识别 · 计算机科学 2024-05-24 Moises Diaz , Miguel Angel Ferrer , Donato Impedovo , Giuseppe Pirlo , Gennaro Vessio

Discriminating between Parkinson's Disease (PD) and Progressive Supranuclear Palsy (PSP) is difficult due to overlapping symptoms, especially early on. Saccades (rapid conjugate eye movements between fixation points) are affected by both…

定量方法 · 定量生物学 2024-07-25 Salil B Patel , Oliver B Bredemeyer , James J FitzGerald , Chrystalina A Antoniades

Deep neural networks have shown potential in analyzing digitized hand-drawn signals for early diagnosis of Parkinson's disease. However, the lack of clear interpretability in existing diagnostic methods presents a challenge to clinical…

计算机视觉与模式识别 · 计算机科学 2025-05-08 Xuechao Wang , Sven Nomm , Junqing Huang , Kadri Medijainen , Aaro Toomela , Michael Ruzhansky

Parkinson's Disease (PD) is a chronic and progressive neurological disorder that results in rigidity, tremors and postural instability. There is no definite medical test to diagnose PD and diagnosis is mostly a clinical exercise. Although…

图像与视频处理 · 电气工程与系统科学 2021-07-28 Shanmukh Alle , U. Deva Priyakumar

Parkinson's disease (PD) is a neuro-degenerative disorder that affects movement, speech, and coordination. Timely diagnosis and treatment can improve the quality of life for PD patients. However, access to clinical diagnosis is limited in…

计算机视觉与模式识别 · 计算机科学 2024-02-19 Md. Zarif Ul Alam , Md Saiful Islam , Ehsan Hoque , M Saifur Rahman

Parkinson's disease (PD) poses challenges in diagnosis and monitoring due to its progressive nature and complex symptoms. This study introduces a novel approach utilizing surface electromyography (sEMG) to objectively assess PD severity,…

Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

神经元与认知 · 定量生物学 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

Parkinson's Disease (PD) is a neurodegenerative disease that currently does not have a cure. In order to facilitate disease management and reduce the speed of symptom progression, early diagnosis is essential. The current clinical,…

图像与视频处理 · 电气工程与系统科学 2019-09-11 Justin Quan , Lin Xu , Rene Xu , Tyrael Tong , Jean Su

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

定量方法 · 定量生物学 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Parkinson's Disease (PD) is a neurological disorder that affects facial movements and non-verbal communication. Patients with PD present a reduction in facial movements called hypomimia which is evaluated in item 3.2 of the MDS-UPDRS-III…

计算机视觉与模式识别 · 计算机科学 2020-12-14 Luis Felipe Gomez-Gomez , Aythami Morales , Julian Fierrez , Juan Rafael Orozco-Arroyave

Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and…

机器学习 · 计算机科学 2022-06-09 Pierluigi Costanzo , Kalia Orphanou

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Lilia Lazli

PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…

神经元与认知 · 定量生物学 2023-09-20 Iman Beheshti , Samuel Booth , Ji Hyun Ko

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

定量方法 · 定量生物学 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

Speech-based Parkinson's disease (PD) detection has gained attention for its automated, cost-effective, and non-intrusive nature. As research studies usually rely on data from diagnostic-oriented speech tasks, this work explores the…

音频与语音处理 · 电气工程与系统科学 2025-08-29 Terry Yi Zhong , Esther Janse , Cristian Tejedor-Garcia , Louis ten Bosch , Martha Larson

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

定量方法 · 定量生物学 2020-08-04 Sanjukta Krishnagopal

In this paper, an interpretable classifier using an interval type-2 fuzzy neural network for detecting patients suffering from Parkinson's Disease (PD) based on analyzing the gait cycle is presented. The proposed method utilizes clinical…

机器学习 · 计算机科学 2022-11-30 Armin Salimi-Badr , Mohammad Hashemi , Hamidreza Saffari

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction and abnormal neural oscillations. These symptoms can be modulated through electrical stimulation. Traditional neural activity analysis in PD has…

神经元与认知 · 定量生物学 2025-02-19 Jibum Kim , Hanseul Choi , Gaeun Kim , Sunggu Yang , Eunha Baeg , Donggue Kim , Seongwon Jin , Sangwon Byun