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Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Conditional score-based diffusion model (SBDM) is for conditional generation of target data with paired data as condition, and has achieved great success in image translation. However, it requires the paired data as condition, and there…

计算机视觉与模式识别 · 计算机科学 2023-11-03 Xiang Gu , Liwei Yang , Jian Sun , Zongben Xu

Uncertainty estimation is a standard tool to quantify the reliability of modern deep learning models, and crucial for many real-world applications. However, efficient uncertainty estimation methods for spiking neural networks, particularly…

机器学习 · 计算机科学 2024-12-03 Tao Sun , Sander Bohté

Observational studies are valuable tools for inferring causal effects in the absence of controlled experiments. However, these studies may be biased due to the presence of some relevant, unmeasured set of covariates. One approach to…

统计方法学 · 统计学 2026-02-17 William Bekerman , Abhinandan Dalal , Carlo del Ninno , Dylan S. Small

Functional data analysis, which handles data arising from curves, surfaces, volumes, manifolds and beyond in a variety of scientific fields, is a rapidly developing area in modern statistics and data science in the recent decades. The…

统计方法学 · 统计学 2020-08-21 Xiaoke Zhang , Wu Xue , Qiyue Wang

We recently developed a new method riAFT-BART to draw causal inferences about population treatment effect on patient survival from clustered and censored survival data while accounting for the multilevel data structure. The practical…

统计方法学 · 统计学 2023-08-14 Liangyuan Hu

In this dissertation we propose alternative analysis of distributed stochastic gradient descent (SGD) algorithms that rely on spectral properties of the data covariance. As a consequence we can relate questions pertaining to speedups and…

最优化与控制 · 数学 2016-09-03 Avleen S. Bijral

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

统计方法学 · 统计学 2025-12-10 Mengqi Lin , Colin Fogarty

Estimating conditional average treatment effects (CATE) from randomized controlled trials (RCTs) and generalizing them to broader populations is essential for personalizing treatment rules but is complicated by selection bias due to trial…

统计方法学 · 统计学 2026-05-15 Rikuta Hamaya , Etsuji Suzuki , Konan Hara

In epidemiological cohort studies, the relative risk (also known as risk ratio) is a major measure of association to summarize the results of two treatments or exposures. Generally, it measures the relative change in disease risk as a…

统计方法学 · 统计学 2022-07-05 Gopal Nath , Krishna K. Saha , Suojin Wang

Standard (network) meta-analysis methods for medical test accuracy evaluation analyse the data separately for each test threshold - wasting data - unless every study reports all thresholds. Previously proposed "multiple threshold" models…

The difference-in-differences (DID) method identifies the average treatment effects on the treated (ATT) under mainly the so-called parallel trends (PT) assumption. The most common and widely used approach to justify the PT assumption is…

计量经济学 · 经济学 2023-08-23 Kyunghoon Ban , Désiré Kédagni

Programming Knowledge Tracing (PKT) has recently advanced through hybrid approaches that integrate attention-based feature modeling for code representation with RNN-based sequential prediction. While these models report strong empirical…

机器学习 · 计算机科学 2026-05-07 Jaewook Kim , Hyeoncheol Kim

Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in the study population. Indeed, an effect…

We study hybrid control trials (HCTs), in which a randomized controlled trial (RCT) is augmented with external control patients. Existing approaches for HCTs typically assume conditional exchangeability of the concurrent and external…

统计方法学 · 统计学 2025-11-21 Alissa Gordon , Emilie Højbjerre-Frandsen , Alejandro Schuler

Tie-breaker experimental designs are hybrids of Randomized Controlled Trials (RCTs) and Regression Discontinuity Designs (RDDs) in which subjects with moderate scores are placed in an RCT while subjects with extreme scores are…

统计方法学 · 统计学 2023-01-24 Dan M. Kluger , Art B. Owen

Gene expression levels, hormone secretion, and internal body temperature each oscillate over an approximately 24-hour cycle, or display circadian rhythms. Many circadian biology studies have investigated how these rhythms vary across…

Inferring the causal effect of a treatment on an outcome in an observational study requires adjusting for observed baseline confounders to avoid bias. However, adjusting for all observed baseline covariates, when only a subset are…

统计方法学 · 统计学 2021-02-04 Wen Wei Loh , Stijn Vansteelandt

In this paper, we propose a distributionally robust control synthesis for an agent with stochastic dynamics that interacts with other agents under uncertainties and constraints expressed by signal temporal logic (STL). We formulate the…

系统与控制 · 电气工程与系统科学 2025-03-14 Arash Bahari Kordabad , Eleftherios E. Vlahakis , Lars Lindemann , Sebastien Gros , Dimos V. Dimarogonas , Sadegh Soudjani

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

应用统计 · 统计学 2008-11-12 Donald B. Rubin
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