相关论文: Distributed Multivariate Regression Modeling For S…

Privacy protection of users' entire contribution of samples is important in distributed systems. The most effective approach is the two-stage scheme, which finds a small interval first and then gets a refined estimate by clipping samples…

In genomic studies, identifying biomarkers associated with a variable of interest is a major concern in biomedical research. Regularized approaches are classically used to perform variable selection in high-dimensional linear models.…

The massive deployment of Machine Learning (ML) models raises serious concerns about data protection. Privacy-enhancing technologies (PETs) offer a promising first step, but hard challenges persist in achieving confidentiality and…

Differentially private data generation techniques have become a promising solution to the data privacy challenge -- it enables sharing of data while complying with rigorous privacy guarantees, which is essential for scientific progress in…

The use of multiple Decision Models (DMs) enables to enhance the accuracy in decisions and at the same time allows users to evaluate the confidence in decision making. In this paper we explore the ability of multiple DMs to learn from a…

Machine learning tasks involving biomedical signals frequently grapple with issues such as limited data availability, imbalanced datasets, labeling complexities, and the interference of measurement noise. These challenges often hinder the…

Data sharing enables critical advances in many research areas and business applications, but it may lead to inadvertent disclosure of sensitive summary statistics (e.g., means or quantiles). Existing literature only focuses on protecting a…

In privacy-preserving machine learning, individual parties are reluctant to share their sensitive training data due to privacy concerns. Even the trained model parameters or prediction can pose serious privacy leakage. To address these…

Distribution Regression (DR) on stochastic processes describes the learning task of regression on collections of time series. Path signatures, a technique prevalent in stochastic analysis, have been used to solve the DR problem. Recent…

We tackle modelling and inference for variable selection in regression problems with many predictors and many responses. We focus on detecting hotspots, i.e., predictors associated with several responses. Such a task is critical in…

In large-scale distributed scenarios, increasingly complex tasks demand more intelligent collaboration across networks, requiring the joint extraction of structural representations from data samples. However, conventional task-specific…

We propose a novel federated learning paradigm to model data variability among heterogeneous clients in multi-centric studies. Our method is expressed through a hierarchical Bayesian latent variable model, where client-specific parameters…

Integrative analysis of datasets generated by multiple cohorts is a widely-used approach for increasing sample size, precision of population estimators, and generalizability of analysis results in epidemiological studies. However, often…

Current statistical inference problems in areas like astronomy, genomics, and marketing routinely involve the simultaneous testing of thousands -- even millions -- of null hypotheses. For high-dimensional multivariate distributions, these…

Multilabel classification is an important problem in a wide range of domains such as text categorization and music annotation. In this paper, we present a probabilistic model, Multilabel Logistic Regression with Hidden variables (MLRH),…

Pooling specimens, a well-accepted sampling strategy in biomedical research, can be applied to reduce the cost of studying biomarkers. Even if the cost of a single assay is not a major restriction in evaluating biomarkers, pooling can be a…

Distributed control/optimization is a promising approach for network systems due to its advantages over centralized schemes, such as robustness, cost-effectiveness, and improved privacy. However, distributed methods can have drawbacks, such…

Identifying co-varying causal elements in very high dimensional feature space with internal structures, e.g., a space with as many as millions of linearly ordered features, as one typically encounters in problems such as whole genome…

One-shot federated learning enables multi-site inference with minimal communication. However, sharing summary statistics can still leak sensitive individual-level information when sites have only a small number of patients. In particular,…

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…