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Synthesizing information from multiple data sources is crucial for constructing accurate individualized treatment rules (ITRs). However, privacy concerns often present significant barriers to the integrative analysis of such multi-source…

统计方法学 · 统计学 2025-11-11 Nan Qiao , Wangcheng Li , Jingxiao Zhang , Canyi Chen

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

统计方法学 · 统计学 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

Accurate diagnostic tests are essential for effective screening and treatment. However, individual biomarkers often fail to provide sufficient diagnostic accuracy, as they typically capture only one aspect of the complex disease process.…

统计方法学 · 统计学 2025-07-08 Ainesh Sewak , Sandra Siegfried , Torsten Hothorn

Distributed statistical analyses provide a promising approach for privacy protection when analysing data distributed over several databases. It brings the analysis to the data and not the data to the analysis. The analyst receives anonymous…

统计计算 · 统计学 2023-03-15 Daniel Schalk , Verena S. Hoffmann , Bernd Bischl , Ulrich Mansmann

Differential privacy is known to protect against threats to validity incurred due to adaptive, or exploratory, data analysis -- even when the analyst adversarially searches for a statistical estimate that diverges from the true value of the…

密码学与安全 · 计算机科学 2022-07-25 Elbert Du , Cynthia Dwork

Pooling biomarker data across multiple studies allows for examination of a wider exposure range than generally possible in individual studies, evaluation of population subgroups and disease subtypes with more statistical power, and more…

统计方法学 · 统计学 2019-06-04 Abigail Sloan , Molin Wang

Distribution regression refers to the supervised learning problem where labels are only available for groups of inputs instead of individual inputs. In this paper, we develop a rigorous mathematical framework for distribution regression…

机器学习 · 计算机科学 2021-09-30 Maud Lemercier , Cristopher Salvi , Theodoros Damoulas , Edwin V. Bonilla , Terry Lyons

As datasets grow larger, they are often distributed across multiple machines that compute in parallel and communicate with a central machine through short messages. In this paper, we focus on sparse regression and propose a new procedure…

统计方法学 · 统计学 2023-03-14 Sifan Liu , Snigdha Panigrahi

We develop a model-based methodology for integrating gene-set information with an experimentally-derived gene list. The methodology uses a previously reported sampling model, but takes advantage of natural constraints in the…

统计方法学 · 统计学 2015-06-02 Zhishi Wang , Qiuling He , Bret Larget , Michael A. Newton

Data sharing barriers are paramount challenges arising from multicenter clinical trials where multiple data sources are stored in a distributed fashion at different local study sites. Merging such data sources into a common data storage for…

统计方法学 · 统计学 2022-04-05 Mengtong Hu , Xu Shi , Peter X. -K. Song

Data analysis based on information from several sources is common in economic and biomedical studies. This setting is often referred to as the data fusion problem, which differs from traditional missing data problems since no complete data…

统计方法学 · 统计学 2022-04-07 Wei Li , Shanshan Luo , Wangli Xu

Meta-analysis, because of both logistical convenience and statistical efficiency, is widely popular for synthesizing information on common parameters of interest across multiple studies. We propose developing a generalized meta-analysis…

统计方法学 · 统计学 2018-11-27 Prosenjit Kundu , Runlong Tang , Nilanjan Chatterjee

We develop a new method for multivariate scalar on multidimensional distribution regression. Traditional approaches typically analyze isolated univariate scalar outcomes or consider unidimensional distributional representations as…

统计方法学 · 统计学 2023-10-17 Rahul Ghosal , Marcos Matabuena

Food authenticity studies are concerned with determining if food samples have been correctly labeled or not. Discriminant analysis methods are an integral part of the methodology for food authentication. Motivated by food authenticity…

统计方法学 · 统计学 2010-10-08 Thomas Brendan Murphy , Nema Dean , Adrian E. Raftery

In many remote sensing applications one wants to estimate variables or parameters of interest from observations. When the target variable is available at a resolution that matches the remote sensing observations, standard algorithms such as…

In many applications, it is of interest to identify a parsimonious set of features, or panel, from multiple candidates that achieves a desired level of performance in predicting a response. This task is often complicated in practice by…

统计方法学 · 统计学 2025-10-23 B. D. Williamson , Y. Huang

In distributed, or privacy-preserving learning, we are often given a set of probabilistic models estimated from different local repositories, and asked to combine them into a single model that gives efficient statistical estimation. A…

机器学习 · 统计学 2017-03-01 Jun Han , Qiang Liu

In recent years, with the development of microarray technique, discovery of useful knowledge from microarray data has become very important. Biclustering is a very useful data mining technique for discovering genes which have similar…

计算工程、金融与科学 · 计算机科学 2009-09-09 Mohsen lashkargir , S. Amirhassan Monadjemi , Ahmad Baraani Dastjerdi

In recent years, an increasing amount of data is collected in different and often, not cooperative, databases. The problem of privacy-preserving, distributed calculations over separated databases and, a relative to it, issue of private data…

数据库 · 计算机科学 2016-05-23 Philip Derbeko , Shlomi Dolev , Ehud Gudes , Jeffrey D. Ullman

We propose a novel regression adjustment method designed for estimating distributional treatment effect parameters in randomized experiments. Randomized experiments have been extensively used to estimate treatment effects in various…

计量经济学 · 经济学 2024-07-24 Undral Byambadalai , Tatsushi Oka , Shota Yasui