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Motivated by recent experimental studies, we derive and analyze a twodimensional model for the contraction patterns observed in protoplasmic droplets of Physarum polycephalum. The model couples a model of an active poroelastic two-phase…

斑图形成与孤子 · 物理学 2018-11-21 Markus Radszuweit , Harald Engel , Markus Bär

The aim of this work is to quantify the spatio-temporal dynamics of flow-driven amoeboid locomotion in small ($\sim$100 $\mu$m) fragments of the true slime mold \phys {\it polycephalum}. In this model organism, cellular contraction drives…

细胞行为 · 定量生物学 2017-05-24 Shun Zhang , Robert D. Guy , Juan C. Lasheras , Juan C. del Alamo

Tissue remodelling in diverse developmental contexts require cell shape changes that have been associated with pulsation and flow of the actomyosin cytoskeleton. Here we describe the dynamics of the actomyosin cytoskeleton as a confined…

生物物理 · 物理学 2016-05-25 Deb Sankar Banerjee , Akankshi Munjal , Thomas Lecuit , Madan Rao

The slime mould Physarum polycephalum is a suitable candidate organism for soft-matter robotics because it exhibits controllable transport, movement and guidance behaviour. Physarum may be considered as a smart computing and actuating…

适应与自组织系统 · 物理学 2012-12-05 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky

Inspired by recent experiments of cells accumulating on anisotropic substrates, we study a two-dimensional, compressible, isotropic, active fluid in the presence of anisotropic friction. We find that regions of anisotropic friction that are…

软凝聚态物质 · 物理学 2026-03-04 Cody D. Schimming , Brian A. Camley

We investigate and model the initiation of motion of a single particle on a structured substrate within an oscillatory boundary layer flow, following a mechanistic approach. By deterministically relating forces and torques acting on the…

This contribution reports on numerical simulations of 2D granular flows on erodible beds. The broad aim is to investigate whether simple flows of model granular matter exhibits spontaneous oscillatory motion in generic flow conditions, and…

软凝聚态物质 · 物理学 2012-11-27 Lydie Staron

We consider two minimal models of active fluid droplets that exhibit complex dynamics including steady motion, deformation, rotation and oscillating motion. First we consider a droplet with a concentration of active contractile matter…

软凝聚态物质 · 物理学 2016-12-20 Carl A. Whitfield , Rhoda J. Hawkins

The fluid-structure interactions between flexible fibers and viscous flows play an essential role in various biological phenomena, medical problems, and industrial processes. Of particular interest is the case of particles freely…

流体动力学 · 物理学 2023-02-01 Francesco Bonacci , Brato Chakrabarti , David Saintillan , Olivia du Roure , Anke Lindner

We model analytically the dynamics of a cytoskeletal filament in a motility assay. The filament is described as rigid rod free to slide in two dimensions. The motor proteins consist of polymeric tails tethered to the plane and modeled as…

统计力学 · 物理学 2015-03-19 Shiladitya Banerjee , M. Cristina Marchetti , Kristian Müller-Nedebock

The slime mould Physarum polycephalum has emerged as a model for self-organisation and coordination of contractile activity at large spatial scales. This self-organisation largely results from cytoplasmic flows generated by propagating…

软凝聚态物质 · 物理学 2025-09-23 Raphael Saiseau , Valentin Busson , Marc Durand

Droplet deformations caused by substrate vibrations are ubiquitous in nature and highly relevant for applications such as microreactors and single-cell sorting. The vibrations can induce droplet oscillations, a fundamental process that…

For various cell types and for lamellipodial fragments on flat surfaces, externally induced and spontaneous transitions between symmetric nonmoving states and polarized migration have been observed. This behavior is indicative of…

细胞行为 · 定量生物学 2015-11-30 Stefanie Hirsch , Angelika Manhart , Christian Schmeiser

The propulsion of mammalian spermatozoa relies on the spontaneous periodic oscillation of their flagella. These oscillations are driven internally by the coordinated action of ATP-powered dynein motors that exert sliding forces between…

流体动力学 · 物理学 2022-10-13 Chenji Li , Brato Chakrabarti , Pedro Castilla , Achal Mahajan , David Saintillan

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

生物物理 · 物理学 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch

Single and collective cellular oscillations involving the actomyosin cytoskeleton have been observed in numerous biological systems. We show here that a generic model of a contractile material, which is turning over and contracts against an…

生物物理 · 物理学 2014-02-24 Kai Dierkes , Angughali Sumi , Jérôme Solon , Guillaume Salbreux

Despite the ubiquity of fluid flows interacting with porous and elastic materials, we lack a validated non-empirical macroscale method for characterizing the flow over and through a poroelastic medium. We propose a computational tool to…

流体动力学 · 物理学 2017-03-24 Uǧis Lācis , Giuseppe Antonio Zampogna , Shervin Bagheri

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

适应与自组织系统 · 物理学 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

We analyze the migration characteristics of a droplet in an oscillatory flow field in a parallel plate micro-confinement. Using phase filed formalism, we capture the dynamical evolution of the droplet over a wide range of the frequency of…

流体动力学 · 物理学 2016-02-17 Kaustav Chaudhury , Shubhadeep Mandal , Suman Chakraborty

It is known from the wave-like motion of microtubules in motility assays that the piconewton forces that motors produce can be sufficient to bend the filaments. In cellular phenomena such as cytosplasmic streaming, molecular motors…

软凝聚态物质 · 物理学 2017-07-11 Gabriele De Canio , Eric Lauga , Raymond E. Goldstein
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