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Transduction of mechanical stimuli into biochemical signals is a fundamental subject for cell physics. In the experiments of FRET signal in cells a wave propagation in nanoscope was observed. We here develop a diffusion wave concept and try…

生物物理 · 物理学 2012-10-31 Tian You Fan , Lei Fan

We propose a model to study symmetric binary fluids, based in the mesoscopic molecular simulation technique known as multiparticle collision, where space and state variables are continuous while time is discrete. We include a repulsion rule…

适应与自组织系统 · 物理学 2016-06-22 C. Echeverria , K. Tucci , O. Alvarez-Llamoza , E. E. Orozco-Guillén , M. Morales , M. G. Cosenza

Dissipative particle dynamics (DPD) belongs to a class of models and computational algorithms developed to address mesoscale problems in complex fluids and soft matter in general. It is based on the notion of particles that represent…

统计力学 · 物理学 2017-05-24 Pep Español , Patrick B Warren

Deep learning has shown great potential for modeling the physical dynamics of complex particle systems such as fluids. Existing approaches, however, require the supervision of consecutive particle properties, including positions and…

机器学习 · 计算机科学 2022-06-22 Shanyan Guan , Huayu Deng , Yunbo Wang , Xiaokang Yang

Molecular fragment or embedding methods are powerful techniques for overcoming scalability limitations in electronic structure theory by dividing large molecular systems into individual units that are small enough to be treated using…

化学物理 · 物理学 2017-08-14 Jason N. Byrd , Robert W. Molt, , Rodney J. Bartlett , Beverly A. Sanders

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

亚细胞过程 · 定量生物学 2019-04-03 Richard P. Sear

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

软凝聚态物质 · 物理学 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Small finite-size particles suspended in fluid flow through an enclosed curved duct can focus to points or periodic orbits in the two-dimensional duct cross-section. This particle focusing is due to a balance between inertial lift forces…

流体动力学 · 物理学 2024-11-20 Rahil N. Valani , Brendan Harding , Yvonne M. Stokes

We study (by an exact numerical scheme) the single-particle density matrix of $\sim 10^3$ ultracold atoms in an optical lattice with a parabolic confining potential. Our simulation is directly relevant to the interpretation and further…

凝聚态物理 · 物理学 2009-11-07 V. A. Kashurnikov , N. V. Prokof'ev , B. V. Svistunov

Constrictions in blood vessels and microfluidic devices can dramatically change the spatial distribution of passing cells or particles and are commonly used in biomedical cell sorting applications. However, the three-dimensional nature of…

流体动力学 · 物理学 2019-12-03 Asena Abay , Steffen M. Recktenwald , Thomas John , Lars Kaestner , Christian Wagner

Electrohydrodynamics is crucial in many nanofluidic and biotechnological applications. In such small scales, the complexity due to the coupling of fluid dynamics with the dynamics of ions is increased by the relevance of thermal…

流体动力学 · 物理学 2022-01-19 Alberto Gubbiotti , Mauro Chinappi , Carlo Massimo Casciola

The recently established connection between stochastic thermodynamics and fluctuating hydrodynamics is applied to a study of efficiencies in the coupled transport of heat and matter on a small scale. A stochastic model for a mesoscopic cell…

统计力学 · 物理学 2019-04-01 Jean-François Derivaux , Yannick De Decker

Particles suspended in a fluid flow through a curved duct can focus to specific locations within the duct cross-section. This particle focusing is a result of a balance between two dominant forces acting on the particle: (i) the inertial…

动力系统 · 数学 2024-01-17 Rahil N. Valani , Brendan Harding , Yvonne M. Stokes

Replication through cell division is one of the most fundamental processes of life and a major driver of dynamics in systems ranging from bacterial colonies to embryogenesis, tissues and tumors. While regulation often plays a role in…

软凝聚态物质 · 物理学 2024-10-21 Lukas Hupe , Yoav G. Pollack , Jonas Isensee , Aboutaleb Amiri , Ramin Golestanian , Philip Bittihn

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

亚细胞过程 · 定量生物学 2015-05-20 Pierre Sens , Matthew S. Turner

Recent experiments in cell biology have probed the impact of artificially-induced intracellular flows in the spatiotemporal organisation of cells and organisms. In these experiments, mild dynamical heating via focused infrared light from a…

流体动力学 · 物理学 2023-04-10 Weida Liao , Elena Erben , Moritz Kreysing , Eric Lauga

An implicit Euler finite-volume scheme for general cross-diffusion systems with volume-filling constraints is proposed and analyzed. The diffusion matrix may be nonsymmetric and not positive semidefinite, but the diffusion system is assumed…

数值分析 · 数学 2021-05-13 Ansgar Jüngel , Antoine Zurek

Ordinary differential equations (ODEs) can model the transition of cell states over time. Bifurcation theory is a branch of dynamical systems which studies changes in the behavior of an ODE system while one or more parameters are varied. We…

细胞行为 · 定量生物学 2023-07-06 Brenda Delamonica , Gabor Balazsi , Michael Shub

High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

生物物理 · 物理学 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

Inertial microfluidics has been limited to dilute particle concentrations due to defocusing (spreading out) at high particle concentrations. We observe a counterintuitive shift of focusing to the outer curved wall under high concentration…

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