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We studied the structuredness in a chloroplast genome of Siberian larch. The clusters in 63-dimensional space were identified with elastic map technique, where the objects to be clusterized are the different fragments of the genome. A…

基因组学 · 定量生物学 2016-04-18 Michael G. Sadovsky , Eugenia I. Bondar , Yuliya A. Putintseva , Konstantin V. Krutovsky

Coding information is the main source of heterogeneity (non-randomness) in the sequences of bacterial genomes. This information can be naturally modeled by analysing cluster structures in the "in-phase" triplet distributions of relatively…

基因组学 · 定量生物学 2011-11-09 A. N. Gorban , T. G. Popova , A. Yu. Zinovyev

In several recent papers new gene-detection algorithms were proposed for detecting protein-coding regions without requiring learning dataset of already known genes. The fact that unsupervised gene-detection is possible closely connected to…

无序系统与神经网络 · 物理学 2007-05-23 A. N. Gorban , A. Yu. Zinovyev , T. G. Popova

Due to the recent evolution of sequencing techniques, the number of available genomes is rising steadily, leading to the possibility to make large scale genomic comparison between sets of close species. An interesting question to answer is:…

计算工程、金融与科学 · 计算机科学 2014-09-24 Bassam AlKindy , Jean-François Couchot , Christophe Guyeux , Arnaud Mouly , Michel Salomon , Jacques M. Bahi

The aim of this study is to investigate the relation that can be found between the phylogeny of a large set of complete chloroplast genomes, and the evolution of gene content inside these sequences. Core and pan genomes have been computed…

基因组学 · 定量生物学 2016-09-21 Bashar Al-Nuaimi , Christophe Guyeux , Bassam AlKindy , Jean-François Couchot , Michel Salomon

The structure of nanoclusters is complex to describe due to their noncrystallinity, even though bonding and packing constraints limit the local atomic arrangements to only a few types. A computational scheme is presented to extract…

材料科学 · 物理学 2009-11-13 Zhu Yang , Lei-Han Tang

While bacterial chromosomes were long thought to be amorphous, recent experiments reveal pronounced organizational features. However, the extent of bacterial chromosome organization remains unclear. Here, we develop a fully data-driven…

Clusters of galaxies are often embedded in larger-scale superclusters with dimensions of tens or perhaps even hundreds of Mpc. Observational and theoretical evidence suggest an important connection between cluster properties and their…

天体物理学 · 物理学 2009-09-25 Michael J. West

Chloroplasts regulate their growth to optimize photosynthesis. Quantitative data shows that the ratio of total chloroplast area to mesophyll cell area is constant across different cells within a single species, and also across species.…

亚细胞过程 · 定量生物学 2015-09-03 Kelly M. Paton , Lisa Anderson , Pauline Flottat , Eric N. Cytrynbaum

We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across…

基因组学 · 定量生物学 2017-11-09 Sarosh N. Fatakia , Ishita S. Mehta , Basuthkar J. Rao

The expression levels of many thousands of genes can be measured simultaneously by DNA microarrays (chips). This novel experimental tool has revolutionized research in molecular biology and generated considerable excitement. A typical…

生物物理 · 物理学 2007-05-23 Eytan Domany

Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…

生物物理 · 物理学 2009-11-07 Erik van Nimwegen , Mihaela Zavolan , Nikolaus Rajewsky , Eric D. Siggia

In condensed matter physics, simplified descriptions are obtained by coarse-graining the features of a system at a certain characteristic length, defined as the typical length beyond which some properties are no longer correlated. From a…

基因组学 · 定量生物学 2018-04-18 Ivan Junier , Paul Frémont , Olivier Rivoire

This is a review of a set of recent papers with some new data added. After a brief biological introduction a visualization scheme of the string composition of long DNA sequences, in particular, of bacterial complete genomes, will be…

软凝聚态物质 · 物理学 2009-10-31 Bai-lin Hao

The study of the internal structure of star clusters provides important clues concerning their formation mechanism and dynamical evolution. There are both observational and numerical evidences indicating that open clusters evolve from an…

星系天体物理 · 物理学 2011-09-15 Emilio Alfaro , Nestor Sanchez

We use two high resolution CDM simulations to show that (i) when clusters of galaxies form the infall pattern of matter is not random but shows clear features which are correlated in time; (ii) in addition, the infall patterns are…

天体物理学 · 物理学 2007-05-23 J. M. Colberg , S. D. M. White , A. Jenkins , F. R. Pearce

In this work we seek clusters of genomic words in human DNA by studying their inter-word lag distributions. Due to the particularly spiked nature of these histograms, a clustering procedure is proposed that first decomposes each…

应用统计 · 统计学 2021-01-13 Ana Helena Tavares , Jakob Raymaekers , Peter J. Rousseeuw , Paula Brito , Vera Afreixo

It has recently been proposed that proteins embedded in lipidic bio-membranes can spontaneously self-organize into stable small clusters, or membrane nano-domains, due to the competition between short-range attractive and longer-range…

软凝聚态物质 · 物理学 2011-06-08 Nicolas Meilhac , Nicolas Destainville

An approximation to the ~4 Mbp basic genome shared by 32 strains of E. coli representing six evolutionary groups has been derived and analyzed computationally. A multiple-alignment of the 32 complete genome sequences was filtered to remove…

基因组学 · 定量生物学 2016-02-17 Purushottam Dixit , Tin Yau Pang , F. William Studier , Sergei Maslov

Clustering is typically measured by the ratio of triangles to all triples, open or closed. Generating clustered networks, and how clustering affects dynamics on networks, is reasonably well understood for certain classes of networks…

物理与社会 · 物理学 2014-10-22 Martin Ritchie , Luc Berthouze , Thomas House , Istvan Z. Kiss
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