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Background: The role of neonatal pain on the developing nervous system is not completely understood, but evidence suggests that sensory pathways are influenced by an infants pain experience. Research has shown that an infants previous pain…

The fundamentals of near infrared spectroscopy (NIRS) are reviewed. This technique allows to measure the oxygenation of the brain tissue. The particular problems involved in detecting regional brain oxygenation (rSO2) are discussed. The…

The technique of near infrared spectroscopy (NIRS) allows to measure the oxygenation of the brain tissue. The particular problems involved in detecting regional brain oxygenation (rSO2) are discussed. The dominant chromophore (light…

Preterm infants are at high risk of developing brain injury in the first days of life as a consequence of poor cerebral oxygen delivery. Near-infrared spectroscopy (NIRS) is an established technology developed to monitor regional tissue…

Near infrared spectroscopy (NIRS) is an optical technique that is widely used to monitor tissue oxygenation. These devices take advantage of the near infrared light to monitor deep tissues like brain, muscle or placenta. In this study, we…

Broadband NIRS (bNIRS) is an extension of fNIRS that provides the same assessment of oxygenation biomarkers along with a valuable marker for oxygen metabolism at a cellular level, the oxidation state of cytochrome-c-oxidase (oxCCO). bNIRS…

Photon scattering has traditionally limited the ability of near-infrared spectroscopy (NIRS) to extract accurate, layer-specific information from the brain. This limitation restricts its clinical utility for precise neurological monitoring.…

Preterm infants with very low birth weight suffer from a high risk of intra-ventricular hemorrhage(IVH) and other serious diseases. To improve the clinical risk assessment of preterm infants and develop potential clinically makers for the…

Apnea-bradycardia is one of the major clinical early indicators of late-onset sepsis occurring in approximately 7% to 10% of all neonates and in more than 25% of very low birth weight infants in NICU. The objective of this paper was to…

This paper proposes a new method to estimate behavioural curves from a stream of Near-Infra-Red (NIR) iris video frames. This method can be used in a Fitness For Duty system (FFD). The research focuses on determining the effect of external…

The motivation of this work is the use of non-invasive and low cost techniques to obtain a faster and more accurate diagnosis of systemic sclerosis (SSc), rheumatic, autoimmune, chronic and rare disease. The technique in question is Near…

The fundamentals of near infrared spectroscopy (NIRS) are reviewed. Among the major factors controlling the cerebral blood flow (CBF), the effect of PaCO2 is peculiar in that it violates autoregulatory CBF mechanisms and allows to explore…

Non-invasive, efficient, physical token-less, accurate and stable identification methods for newborns may prevent baby swapping at birth, limit baby abductions and improve post-natal health monitoring across geographies, within the context…

Conventional near-infrared spectroscopy (NIRS) instruments typically employ 2-3 wavelengths for monitoring tissue haemodynamics. However, the use of broadband illumination (hundreds of wavelengths) unlocks also the targeting of tissue…

Diffusion magnetic resonance imaging (dMRI) enables non-invasive investigation of tissue microstructure. The Standard Model (SM) of white matter aims to disentangle dMRI signal contributions from intra- and extra-axonal water compartments.…

Accurate assessment of tissue perfusion is crucial in visceral surgery, especially during anastomosis. Currently, subjective visual judgment is commonly employed in clinical settings. Hyperspectral imaging (HSI) offers a non-invasive,…

Pressure-sensitive mats (PSM) have proved to be useful in the estimation of respiratory rates (RR) in adult patients. However, PSM technology has not been extensively applied to derive physiologic parameters in infant and neonatal patients.…

Background: A noninvasive and sensitive imaging tool is needed to assess the fast-evolving baby brain. However, using MRI to study non-sedated babies faces roadblocks, including high scan failure rates due to subjects motion and the lack of…

Objective: Non-contact physiological measurement is a growing research area that allows capturing vital signs such as heart rate (HR) and breathing rate (BR) comfortably and unobtrusively with remote devices. However, most of the approaches…

Currently self-report pain ratings are the gold standard in clinical pain assessment. However, the development of objective automatic measures of pain could substantially aid pain diagnosis and therapy. Recent neuroimaging studies have…