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The efficiency of nanopore-based biosequencing techniques requires fast anionic polymer capture by like-charged pores followed by a prolonged translocation process. We show that this condition can be achieved by setting a pressure-solvation…

软凝聚态物质 · 物理学 2018-06-20 Sahin Buyukdagli

Polymer translocation experiments typically involve anionic polyelectrolytes such as DNA molecules driven through negatively charged nanopores. Quantitative modelling of polymer capture to the nanopore followed by translocation therefore…

软凝聚态物质 · 物理学 2017-10-11 Sahin Buyukdagli , Tapio Ala-Nissila

The efficiency of nanopore-based polymer sensing devices depends on the fast capture of anionic polyelectrolytes by negatively charged pores. This requires the cancellation of the electrostatic barrier associated with repulsive polymer-pore…

软凝聚态物质 · 物理学 2017-10-25 Sahin Buyukdagli , Tapio Ala-Nissila

We develop a correlation-corrected transport theory in order to predict ionic and polymer transport properties of membrane nanopores in physical conditions where mean-field electrostatics breaks down. The experimentally observed low KCl…

软凝聚态物质 · 物理学 2014-11-06 Sahin Buyukdagli , Tapio Ala-Nissila

The alteration of the dielectric membrane properties by membrane engineering techniques such as carbon nanotube (CNT) coating opens the way to novel molecular transport strategies for biosensing purposes. In this article, we predict a…

软凝聚态物质 · 物理学 2022-01-12 Sahin Buyukdagli

In this paper we report the theory describing the electro-osmotic flow in charged nanopores with constant radius and charge density driven by alternating current. We solve the ion and solution transport in unsteady conditions as described…

化学物理 · 物理学 2018-10-17 J. Catalano , P. M. Biesheuvel

We investigate electro-osmosis in aqueous solutions of polyelectrolytes using mean-field equations. A solution of positively charged polyelectrolytes is confined between two negatively charged planar surfaces, and an electric field is…

软凝聚态物质 · 物理学 2015-06-16 Yuki Uematsu , Takeaki Araki

Motivated by recent experiments, we present a theoretical investigation of how the electro-osmotic flow occurring in a capillary is modified when its charged surfaces are coated by charged polymers. The theoretical treatment is based on a…

介观与纳米尺度物理 · 物理学 2015-07-17 Umberto Marini Bettolo Marconi , Michele Monteferrante , Simone Melchionna

Electroosmosis is a fascinating effect where liquid motion is induced by an applied electric field. Counter ions accumulate in the vicinity of charged surfaces, triggering a coupling between liquid mass transport and external electric…

Selectivity towards positive and negative ions in nanopores is often associated with electroosmotic flow, the control of which is pivotal in several micro-nanofluidic technologies. Selectivity is traditionally understood to be a consequence…

流体动力学 · 物理学 2022-04-21 Giovanni Di Muccio , Blasco Morozzo della Rocca , Mauro Chinappi

Liquid transport through nanopore is central into many applications, from water purification to biosensing or energy harvesting. Ultimately thin nanopores are of major interest in these applications to increase driving potential and reduce…

流体动力学 · 物理学 2020-10-05 Olivier Liot , Catherine Sempere , Christophe Ybert , Anne-Laure Biance

Single nanopores have attracted much scientific interest due to their versatile applications. The majority of experiments have been performed with nanopores being in contact with the same electrolyte on both sides of the membrane, while…

化学物理 · 物理学 2018-12-11 Yinghua Qiu , Zuzanna S. Siwy , Meni Wanunu

The requirement to boost the resolution of nanopore-based biosequencing devices necessitates the integration of novel biosensing techniques with reduced sensitivity to background noise. In this article, we probe the signatures of…

软凝聚态物质 · 物理学 2023-05-01 Sahin Buyukdagli

Ion transporters in Nature exhibit a wealth of complex transport properties such as voltage gating, activation, and mechanosensitive behavior. When combined, such processes result in advanced ionic machines achieving active ion transport,…

软凝聚态物质 · 物理学 2020-05-08 Laetitia Jubin , Anthony R. Poggioli , Alessandro Siria , Lydéric Bocquet

Porous graphene has high mechanical strength and atomic layer thickness, which make it a promising material for material separation and biomolecule sensing. Electrostatic interactions between charges in aqueous solution are a kind of strong…

化学物理 · 物理学 2016-08-02 Yinghua Qiu , Kun Li , Weiyu Chen , Wei Si , Qiyan Tan , Yunfei Chen

Short nanopores have various applications in biosensing, desalination, and energy conversion. Here, the modulation of charged exterior surfaces on ionic transport is investigated through simulations with sub-200 nm long nanopores under…

软凝聚态物质 · 物理学 2024-02-08 Long Ma , Zhe Liu , Jia Man , Jianyong Li , Zuzanna S. Siwy , Yinghua Qiu

Plasmonic nanopores are extensively investigated as single molecules detectors. The main limitations in plasmonic nanopore technology are the too fast translocation velocity of the molecule through the pore and the consequent very short…

应用物理 · 物理学 2021-05-12 Nicolò Maccaferri , Paolo Vavassori , Denis Garoli

Electrophoretic (EP) mobility reversal is commonly observed for strongly charged macromolecules in multivalent salt solutions. This curious effect takes place, e.g., when a charged polymer, such as DNA, adsorbs excess counterions so that…

软凝聚态物质 · 物理学 2023-03-28 Xiang Yang , Sahin Buyukdagli , Alberto Scacchi , Maria Sammalkorpi , Tapio Ala-Nissila

Electroosmotic pumping of fluid through a nanopore that traverses an insulating membrane is considered. The density of surface charge on the membrane is assumed uniform, and sufficiently low for the Poisson-Boltzmann equation to be…

流体动力学 · 物理学 2014-05-15 M. Mao , J. D. Sherwood , S. Ghosal

Fundamental understanding of ionic transport at the nanoscale is essential for developing biosensors based on nanopore technology and new generation high-performance nanofiltration membranes for separation and purification applications. We…

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