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One of the aims of systems biology is to build multiple layered and multiple scale models of living systems which can efficiently describe phenomena occurring at various level of resolution. Such models should consist of layers of various…

动力系统 · 数学 2015-03-03 Jacek Banasiak , Aleksandra Falkiewicz , Proscovia Namayanja

Mating preferences of many biological species are not constant but season-dependent. Within the framework of evolutionary game theory this can be modeled with two finite opposite-sex populations playing against each other following the…

种群与进化 · 定量生物学 2015-08-13 Olena Tkachenko , Juzar Thingna , Sergey Denisov , Vasily Zaburdaev , Peter Hänggi

A key unresolved question in microbial ecology is how the extraordinary diversity of microbiomes emerges from the behaviour of individual populations. This process is driven by the cross-feeding networks that structure these communities,…

种群与进化 · 定量生物学 2026-04-09 Tom Clegg , Thilo gross

Liquid mixtures of many interacting components often exhibit numerous coexisting types of droplets. An exciting example is the cytosol of biological cells, where diverse droplets, called condensates, are essential for cellular function.…

软凝聚态物质 · 物理学 2025-05-28 Yicheng Qiang , Chengjie Luo , David Zwicker

We present a simple mathematical model that captures the evolutionary capabilities of a prebiotic compartment or protocell. In the model the protocell contains an autocatalytic set whose chemical dynamics is coupled to the growth-division…

种群与进化 · 定量生物学 2023-10-31 Angad Yuvraj Singh , Sanjay Jain

The stable marriage and stable roommates problems have been extensively studied due to their high applicability in various real-world scenarios. However, it might happen that no stable solution exists, or stable solutions do not meet…

计算机科学与博弈论 · 计算机科学 2022-04-29 Kristóf Bérczi , Gergely Csáji , Tamás Király

The stable matching problem has been the subject of intense theoretical and empirical study since the seminal 1962 paper by Gale and Shapley. The number of stable matchings for different systems of preferences has been studied in many…

概率论 · 数学 2024-01-01 Christopher Hoffman , Avi Levy , Elchanan Mossel

Life-history tradeoffs among species are major drivers of community assembly. Most studies investigate how tradeoffs promote deterministic coexistence of species. It remains unclear how tradeoffs may instead promote historically contingent…

种群与进化 · 定量生物学 2021-03-09 Niv DeMalach , Nadav Shnerb , Tadashi Fukami

The multisite phosphorylation-dephosphorylation cycle is a motif repeatedly used in cell signaling. This motif itself can generate a variety of dynamic behaviors like bistability and ultrasensitivity without direct positive feedbacks. In…

定量方法 · 定量生物学 2011-11-09 Liming Wang , Eduardo D. Sontag

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

细胞行为 · 定量生物学 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

Many species of microbes cooperate by producing public goods from which they collectively benefit. However, these populations are under the risk of being taken over by cheating mutants that do not contribute to the pool of public goods.…

种群与进化 · 定量生物学 2023-12-20 Gurdip Uppal , Dervis Can Vural

The emergence of collective cooperation in competitive environments is a well-known phenomenon in biology, economics, and social systems. While most evolutionary game models focus on the evolution of strategies for a fixed game, how…

物理与社会 · 物理学 2024-08-01 Onkar Sadekar , Andrea Civilini , Jesús Gómez-Gardeñes , Vito Latora , Federico Battiston

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

种群与进化 · 定量生物学 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

Ecological modelling of increasingly more complex microbial populations is necessary to reflect the highly functional and diverse behaviour inherent to many systems found in reality. Anaerobic digestion is one such process that has…

动力系统 · 数学 2015-08-24 Tewfik Sari , Matthew J. Wade

New automated and high-throughput methods allow the manipulation and selection of numerous bacterial populations. In this manuscript we are interested in the neutral diversity patterns that emerge from such a setup in which many bacterial…

种群与进化 · 定量生物学 2024-03-13 Guilhem Doulcier , Amaury Lambert

Microscopic strategy update rules play an important role in the evolutionary dynamics of cooperation among interacting agents on complex networks. Many previous related works only consider one \emph{fixed} rule, while in the real world,…

最优化与控制 · 数学 2023-11-27 Shengxian Wang , Weijia Yao , Ming Cao , Xiaojie Chen

We study stable matchings that are robust to preference changes in the two-sided stable matching setting of Gale and Shapley [GS62]. Given two instances $A$ and $B$ on the same set of agents, a matching is said to be robust if it is stable…

计算机科学与博弈论 · 计算机科学 2026-01-14 Rohith Reddy Gangam , Tung Mai , Nitya Raju , Vijay V. Vazirani

We revisit the modeling of the diauxic growth of a pure microorganism on two distinct sugars which was first described by Monod. Most available models are deterministic and make the assumption that all cells of the microbial ecosystem…

种群与进化 · 定量生物学 2020-05-19 Carl Graham , Jérôme Harmand , Sylvie Méléard , Josué Tchouanti

We study the classical, two-sided stable marriage problem under pairwise preferences. In the most general setting, agents are allowed to express their preferences as comparisons of any two of their edges and they also have the right to…

离散数学 · 计算机科学 2018-10-02 Ágnes Cseh , Attila Juhos

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

无序系统与神经网络 · 物理学 2007-05-23 Naoki Masuda , Norio Konno