相关论文: Stress, Depression and Neuroplasticity

Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior. These two attributes -- flexibility and selection -- must…

The coarse-graining of amorphous plasticity from the atomistic to the mesoscopic scale is studied in the framework of a simple scalar elasto-plastic model. Building on recent results obtained on the atomistic scale, we discuss the interest…

Neuromorphic computing is a brainlike information processing paradigm that requires adaptive learning mechanisms. A spiking neuro-evolutionary system is used for this purpose; plastic resistive memories are implemented as synapses in…

Intertemporal choice has drawn attention in behavioral economics, econophysics, and neuroeconomics. Recent studies in mainstream economics have mainly focused on inconsistency in intertemporal choice (dynamic inconsistency); while…

Disordered solids often change their elastic response as they slowly age. Using experiments and simulations, we study how aging disordered planar networks under an applied stress affects their nonlinear elastic response. We are able to…

The interior of nanoscale crystals experiences stress that compensates the capillary forces and that can be large, in the order of 1 GPa. Various studies have speculated on whether and how this surface-induced stress affects the stability…

As both our external world and inner worlds become more complex, we are faced with more novel challenges, hardships, and duress. Creative thinking is needed to provide fresh perspectives and solve new problems.Because creativity can be…

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

Over the past decade, the intricacies of sports-related concussions among female athletes have become readily apparent. Traditional clinical methods for diagnosing concussions suffer limitations when applied to female athletes, often…

Multiple sclerosis (MS) is the most common disabling neurological disorders in the young adults. In spite of many researches, the cause of the disease has remained mainly not understood. All evidences indicate that environmental risk…

As we enter the age of designer matter - where objects can morph and change shape on command - what tools do we need to create shape-shifting structures? At the heart of an elastic deformation is the combination of dilation and distortion,…

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Synaptic efficacy between neurons is known to change within a short time scale dynamically. Neurophysiological experiments show that high-frequency presynaptic inputs decrease synaptic efficacy between neurons. This phenomenon is called…

Neural plasticity is an important functionality of human brain, in which number of neurons and synapses can shrink or expand in response to stimuli throughout the span of life. We model this dynamic learning process as an $L_0$-norm…

Development is a complex phenomenon where the forming phenotype interacts with genetic and environmental inputs. Teeth are an important model for developmental studies and their development has been thoroughly investigated. However, despite…

Housing instability is a widespread phenomenon in the United States. In combination with other social determinants of health, housing instability affects children's overall health and development. Drawing on data from the 2022 National…

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

Nerves are frequently stretched during movement. We investigate here the effect of stretch on nerve excitability within the framework of the soliton theory. This thermodynamic theory for nerve pulse propagation relies on the presence of a…

In this work we study, analytically and employing Monte Carlo simulations, the influence of the competition between several activity-dependent synaptic processes, such as short-term synaptic facilitation and depression, on the maximum…

Competitive neural networks are often used to model the dynamics of perceptual bistability. Switching between percepts can occur through fluctuations and/or a slow adaptive process. Here, we analyze switching statistics in competitive…