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Biopolymer gels such as fibrin and collagen networks are known to develop tensile axial stress when subject to torsion. This negative normal stress is opposite to the classical Poynting effect observed for most elastic solids including…

软凝聚态物质 · 物理学 2018-04-04 Mahsa Vahabi , Bart E. Vos , Henri C. G. de Cagny , Daniel Bonn , Gijsje H. Koenderink , F. C. MacKintosh

Hydrogels are biphasic, swollen polymer networks where elastic deformation is coupled to nanoscale fluid flow. As a consequence, hydrogels can withstand large strains and exhibit nonlinear, hyperelastic properties. For low-modulus hydrogel…

软凝聚态物质 · 物理学 2024-10-23 Jing Wang , Justin C. Burton

We present theoretical and experimental studies of the elastic response of fibrous networks subjected to uniaxial strain. Uniaxial compression or extension is applied to extracellular networks of fibrin and collagen using a shear rheometer…

Motivated by recent experiments showing that stiff biopolymer gels exhibit highly unusual negative normal elastic stresses, we develop a computational model for stiff polymer networks subject to large strains. In all cases, we find that…

软凝聚态物质 · 物理学 2009-11-13 Enrico Conti , F. C. MacKintosh

Disordered athermal biopolymer materials, such as collagen networks that constitute a major component in extracellular matrices and various connective tissues, are initially soft and compliant but stiffen dramatically under strain. Such…

软凝聚态物质 · 物理学 2025-09-19 Zibin Zhang , Eran Bouchbinder , Edan Lerner

In this paper we study the elastic response of synthetic hydrogels to an applied shear stress. The hydrogels studied here have previously been shown to mimic the behaviour of biopolymer networks when they are sufficiently far above the gel…

软凝聚态物质 · 物理学 2016-05-05 M. Dennison , M. Jaspers , P. H. J. Kouwer , C. Storm , A. E. Rowan , F. C. MacKintosh

Soft living tissues like cartilage can be considered as biphasic materials comprised of a fibrous complex biopolymer network and a viscous background liquid. Here, we show by a combination of experiment and theoretical analysis that both…

软凝聚态物质 · 物理学 2019-10-02 Melle T. J. J. M. Punter , Bart E. Vos , Bela M. Mulder , Gijsje H. Koenderink

When sheared, most elastic solids such as metals, rubbers and polymer hydrogels dilate in the direction perpendicular to the shear plane. This well-known behaviour known as the Poynting effect is characterized by a positive normal stress.…

Biopolymer networks are common in biological systems from the cytoskeleton of individual cells to collagen in the extracellular matrix. The mechanics of these systems under applied strain can be explained in some cases by a phase transition…

软凝聚态物质 · 物理学 2022-12-21 Sadjad Arzash , Abhinav Sharma , Fred C. MacKintosh

Collagen is the main structural and load-bearing element of various connective tissues, where it forms the extracellular matrix that supports cells. It has long been known that collagenous tissues exhibit a highly nonlinear stress-strain…

The mechanics of disordered fibrous networks such as those that make up the extracellular matrix are strongly dependent on the local connectivity or coordination number. For biopolymer networks this coordination number is typically between…

软凝聚态物质 · 物理学 2019-05-01 Sadjad Arzash , Jordan L. Shivers , Albert J. Licup , Abhinav Sharma , Fred C. MacKintosh

We study the mechanical stiffening behavior in two-dimensional (2D) cross-linked networks of semiflexible biopolymer filaments under simple shear. Filamental constituents immersed in a fluid undergo thermally excited bending motions.…

生物物理 · 物理学 2007-05-23 T. Van Dillen , P. R. Onck , E. Van der Giessen

Dynamically crosslinked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers nonlinearly stiffen in response to mechanical loads, whereas the crosslinker dynamics…

软凝聚态物质 · 物理学 2019-06-05 Yuval Mulla , F. C. MacKintosh , Gijsje H. Koenderink

Naturally occurring protein fibers often undergo anisotropic swelling when hydrated. Within a tendon, a hydrated collagen fibril's radius expands by 40% but its length only increases by 5%. The same effect, with a similar relative…

软凝聚态物质 · 物理学 2024-10-01 Xander A. Gouws , Ana Mastnak , Laurent Kreplak , Andrew D. Rutenberg

Real-world solids, such as rocks, soft tissues, and engineering materials, are often under some form of stress. Most real materials are also, to some degree, anisotropic due to their microstructure, a characteristic often called the…

经典物理 · 物理学 2022-08-09 Soumya Mukherjee , Michel Destrade , Artur L. Gower

Athermal models of disordered fibrous networks are highly useful for studying the mechanics of elastic networks composed of stiff biopolymers. The underlying network architecture is a key aspect that can affect the elastic properties of…

软凝聚态物质 · 物理学 2016-01-20 Albert James Licup , Abhinav Sharma , Fred C. MacKintosh

The first normal stress difference (${\mathcal N}_1$) and the microstructure in a dense sheared granular fluid of smooth inelastic hard-disks are probed using event-driven simulations. While the anisotropy in the second moment of…

软凝聚态物质 · 物理学 2009-11-10 Meheboob Alam , Stefan Luding

Fibre-reinforced hydrogels are promising materials for biomedical applications due to their strength, toughness, and tunability. However, it remains unclear how to design fibre-reinforced hydrogels for use in specific applications due to…

软凝聚态物质 · 物理学 2025-03-26 Matthew G. Hennessy , Tom Shearer , Axel C. Moore

We study computationally the creep and yielding of athermal gels and fibre network materials under a constant imposed shear stress, within a minimal model of interconnected filaments with central forces in $d=2$ spatial dimensions. Each…

软凝聚态物质 · 物理学 2026-01-23 Michael J. Hertaeg , Suzanne M. Fielding

Filamentous bio-materials such as fibrin or collagen networks exhibit an enormous stiffening of their elastic moduli upon large deformations. This pronounced nonlinear behavior stems from a significant separation between the stiffnesses…

软凝聚态物质 · 物理学 2019-05-21 Robbie Rens , Carlos Villarroel , Gustavo Düring , Edan Lerner
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