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This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Systems integration is a difficult matter particularly when its components are varied. The problem becomes even more difficult when such components are heterogeneous such as humans, robots and software systems. Currently, the humans are…

软件工程 · 计算机科学 2014-08-27 Ammar Lahlouhi

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

计算物理 · 物理学 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

Physical analogs have shown considerable promise for understanding the behavior of complex adaptive systems, including macroeconomics, biological systems, social networks, and electric power markets. Many of today's most challenging…

适应与自组织系统 · 物理学 2007-05-23 David P. Chassin , Joel Malard , Christian Posse

In order to build dialogue systems to tackle the ambitious task of holding social conversations, we argue that we need a data driven approach that includes insight into human conversational chit chat, and which incorporates different…

计算与语言 · 计算机科学 2017-09-12 Kevin K. Bowden , Shereen Oraby , Amita Misra , Jiaqi Wu , Stephanie Lukin

Mathematical models are fundamental building blocks in the design of dynamical control systems. As control systems are becoming increasingly complex and networked, approaches for obtaining such models based on first principles reach their…

机器学习 · 计算机科学 2022-07-19 Dominik Baumann , Friedrich Solowjow , Karl H. Johansson , Sebastian Trimpe

Active matter comprises individual units that convert energy into mechanical motion. In many examples, such as bacterial systems and biofilament assays, constituent units are elongated and can give rise to local nematic orientational order.…

软凝聚态物质 · 物理学 2020-11-17 He Li , Xia-qing Shi , Mingji Huang , Xiao Chen , Mingfeng Xiao , Chenli Liu , Hugues Chate , H. P. Zhang

Time-discrete dynamical systems on a finite state space have been used with great success to model natural and engineered systems such as biological networks, social networks, and engineered control systems. They have the advantage of being…

组合数学 · 数学 2015-03-17 Alan Veliz-Cuba , Reinhard Laubenbacher

Mathematical modelling has a long history in the context of collective cell migration, with applications throughout development, disease and regenerative medicine. The aim of modelling in this context is to provide a framework in which to…

定量方法 · 定量生物学 2025-06-24 Ruth E. Baker , Rebecca M. Crossley , Carles Falco , Simon F. Martina-Perez

Data driven algorithm design is an important aspect of modern data science and algorithm design. Rather than using off the shelf algorithms that only have worst case performance guarantees, practitioners often optimize over large families…

数据结构与算法 · 计算机科学 2020-11-17 Maria-Florina Balcan

It is argued that the dynamics of an isolated system, due to the concrete procedure by which it is separated from the environment, has a non-Hamiltonian contribution. By a unified quantum field theoretical treatment of typical subdynamics,…

量子物理 · 物理学 2007-05-23 L. Lanz , O. Melsheimer , B. Vacchini

Many biological and physical systems exhibit behaviour at multiple spatial, temporal or population scales. Multiscale processes provide challenges when they are to be simulated using numerical techniques. While coarser methods such as…

定量方法 · 定量生物学 2018-02-12 Cameron A. Smith , Christian A. Yates

Principles of modern cyber-physical system (CPS) analysis are based on analytical methods that depend on whether safety or liveness requirements are considered. Complexity is abstracted through different techniques, ranging from stochastic…

分布式、并行与集群计算 · 计算机科学 2019-09-02 Eric M. S. P. Veith , Lars Fischer , Martin Tröschel , Astrid Nieße

The development of modern information technologies permits to collect and to analyze huge amounts of statistical data in different spheres of life. The main problem is not to only to collect but to process all relevant information. The…

信息检索 · 计算机科学 2010-07-08 O. Mryglod , Yu. Holovatch

The growing complexity of the power grid, driven by increasing share of distributed energy resources and by massive deployment of intelligent internet-connected devices, requires new modelling tools for planning and operation. Physics-based…

机器学习 · 统计学 2018-11-26 Francesco Fusco

With the explosive growth of big data, workloads tend to get more complex and computationally demanding. Such applications are processed on distributed interconnected resources that are becoming larger in scale and computational capacity.…

分布式、并行与集群计算 · 计算机科学 2025-10-30 Georgios L. Stavrinides , Helen D. Karatza

Background: Distributed data-intensive systems are increasingly designed to be only eventually consistent. Persistent data is no longer processed with serialized and transactional access, exposing applications to a range of potential…

软件工程 · 计算机科学 2021-08-10 Susanne Braun , Stefan Deßloch , Eberhard Wolff , Frank Elberzhager , Andreas Jedlitschka

The real world is awash with multi-agent problems that require collective action by self-interested agents, from the routing of packets across a computer network to the management of irrigation systems. Such systems have local incentives…

多智能体系统 · 计算机科学 2021-02-16 Michiel A. Bakker , Richard Everett , Laura Weidinger , Iason Gabriel , William S. Isaac , Joel Z. Leibo , Edward Hughes

In this paper, we present a critical collection of essential mathematical tools and techniques for the analysis of Boltzmann-type kinetic equations, which in recent years have established themselves as a flexible and powerful paradigm to…

数学物理 · 物理学 2025-03-17 Nadia Loy , Andrea Tosin

We consider the distributed optimization problem, where a group of agents work together to optimize a common objective by communicating with neighboring agents and performing local computations. For a given algorithm, we use tools from…

最优化与控制 · 数学 2020-09-11 Bryan Van Scoy , Laurent Lessard