相关论文: Heritability estimates on resting state fMRI data …

Stochastic neural networks such as Restricted Boltzmann Machines (RBMs) have been successfully used in applications ranging from speech recognition to image classification. Inference and learning in these algorithms use a Markov Chain Monte…

Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to…

Traditionally, heritability has been estimated using family-based methods such as twin studies. Advancements in molecular genomics have facilitated the development of alternative methods that utilise large samples of unrelated or related…

Motivated by applications in neuroanatomy, we propose a novel methodology for estimating the heritability which corresponds to the proportion of phenotypic variance which can be explained by genetic factors. Estimating this quantity for…

Fetal functional Magnetic Resonance Imaging (fMRI) has emerged as a powerful tool for investigating brain development in utero, holding promise for generating developmental disease biomarkers and supporting prenatal diagnosis. However, to…

Single-subject mapping of resting-state brain functional activity to non-imaging phenotypes is a major goal of neuroimaging. The large majority of learning approaches applied today rely either on static representations or on short-term…

This manuscript presents a novel, tightly integrated pipeline for estimating a connectome, which is a comprehensive description of the neural circuits in the brain. The pipeline utilizes magnetic resonance imaging (MRI) data to produce a…

A fundamental challenge in neuroscience is to decode mental states from brain activity. While functional magnetic resonance imaging (fMRI) offers a non-invasive approach to capture brain-wide neural dynamics with high spatial precision,…

MR imaging is a valuable diagnostic tool allowing to non-invasively visualize patient anatomy and pathology with high soft-tissue contrast. However, MRI acquisition is typically time-consuming, leading to patient discomfort and increased…

We present a computational framework for analysis and visualization of non-linear functional connectivity in the human brain from resting state functional MRI (fMRI) data for purposes of recovering the underlying network community structure…

With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic…

Neuroimaging consortia can enhance reliability and generalizability of findings by pooling data across studies to achieve larger sample sizes. To adjust for site and MRI protocol effects, imaging datasets are often harmonized based on…

Automatic segmentation of diverse heterogeneous brain lesions using multi-modal MRI is a challenging problem in clinical neuroimaging, mainly because of the lack of generalizability and high prediction variance of pathology-specific deep…

The human brain is a large-scale network which function depends on dynamic interactions between spatially-distributed regions. In the rapidly-evolving field of network neuroscience, two yet unresolved challenges are potential breakthroughs.…

There has been an explosion of interest in functional Magnetic Resonance Imaging (MRI) during the past two decades. Naturally, this has been accompanied by many major advances in the understanding of the human connectome. These advances…

Effective connectivity can describe the causal patterns among brain regions. These patterns have the potential to reveal the pathological mechanism and promote early diagnosis and effective drug development for cognitive disease. However,…

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Functional magnetic resonance imaging (fMRI) time series are known to exhibit long-range temporal dependencies that challenge traditional modeling approaches. In this study, we propose a novel computational pipeline to characterize and…