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Nonlinear registration of 2D histological sections with corresponding slices of MRI data is a critical step of 3D histology reconstruction. This task is difficult due to the large differences in image contrast and resolution, as well as the…

计算机视觉与模式识别 · 计算机科学 2018-09-28 Juan Eugenio Iglesias , Marc Modat , Loic Peter , Allison Stevens , Roberto Annunziata , Tom Vercauteren , Ed Lein , Bruce Fischl , Sebastien Ourselin

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

计算机视觉与模式识别 · 计算机科学 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Registration of histological and mass spectrometry imaging (MSI) allows for more precise identification of structural changes and chemical interactions in tissue. With histology and MSI having entirely different image formation processes…

图像与视频处理 · 电气工程与系统科学 2025-06-09 Kimberley M. Bird , Xujiong Ye , Alan M. Race , James M. Brown

Recent developments in the registration of histology and micro-computed tomography ({\mu}CT) have broadened the perspective of pathological applications such as virtual histology based on {\mu}CT. This topic remains challenging because of…

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Meva Himmetoglu , Ilja Ciernik , Ender Konukoglu

Whole brain neuroanatomy using tera-voxel light-microscopic data sets is of much current interest. A fundamental problem in this field is the mapping of individual brain data sets to a reference space. Previous work has not rigorously…

神经元与认知 · 定量生物学 2019-04-18 Brian C. Lee , Meng Kuan Lin , Yan Fu , Junichi Hata , Michael I. Miller , Partha P. Mitra

Three-dimensional segmentation in magnetic resonance images (MRI), which reflects the true shape of the objects, is challenging since high-resolution isotropic MRIs are rare and typical MRIs are anisotropic, with the out-of-plane dimension…

图像与视频处理 · 电气工程与系统科学 2023-03-15 Hanxue Gu , Hongyu He , Roy Colglazier , Jordan Axelrod , Robert French , Maciej A Mazurowski

Although the latest advances in MRI technology have allowed the acquisition of higher resolution images, reliable delineation of cytoarchitectural or subcortical nuclei boundaries is not possible. As a result, histological images are still…

Joint registration of a stack of 2D histological sections to recover 3D structure (``3D histology reconstruction'') finds application in areas such as atlas building and validation of \emph{in vivo} imaging. Straightforward pairwise…

图像与视频处理 · 电气工程与系统科学 2021-12-02 Adrià Casamitjana , Marco Lorenzi , Sebastiano Ferraris , Loc Peter , Marc Modat , Allison Stevens , Bruce Fischl , Tom Vercauteren , Juan Eugenio Iglesias

Multi-atlas segmentation is a widely used tool in medical image analysis, providing robust and accurate results by learning from annotated atlas datasets. However, the availability of fully annotated atlas images for training is limited due…

计算机视觉与模式识别 · 计算机科学 2016-05-03 Lisa M. Koch , Martin Rajchl , Wenjia Bai , Christian F. Baumgartner , Tong Tong , Jonathan Passerat-Palmbach , Paul Aljabar , Daniel Rueckert

MRI (Magnetic Resonance Imaging) is a technique used to analyze and diagnose the problem defined by images like cancer or tumor in a brain. Physicians require good contrast images for better treatment purpose as it contains maximum…

计算机视觉与模式识别 · 计算机科学 2020-03-17 Sakshi Patel , Bharath K P , Rajesh Kumar Muthu

Magnetic resonance (MR) protocols rely on several sequences to assess pathology and organ status properly. Despite advances in image analysis, we tend to treat each sequence, here termed modality, in isolation. Taking advantage of the…

计算机视觉与模式识别 · 计算机科学 2020-11-11 Agisilaos Chartsias , Giorgos Papanastasiou , Chengjia Wang , Scott Semple , David E. Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

计算机视觉与模式识别 · 计算机科学 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

In medical image analysis, constructing an atlas, i.e. a mean representative of an ensemble of images, is a critical task for practitioners to estimate variability of shapes inside a population, and to characterise and understand how…

Brightfield and fluorescent imaging of whole brain sections are funda- mental tools of research in mouse brain study. As sectioning and imaging become more efficient, there is an increasing need to automate the post-processing of sec- tions…

计算机视觉与模式识别 · 计算机科学 2018-03-12 Yuncong Chen , David Kleinfeld , Martyn Goulding , Yoav Freund

Skull-stripping separates the skull region of the head from the soft brain tissues. In many cases of brain image analysis, this is an essential preprocessing step in order to improve the final result. This is true for both registration and…

计算机视觉与模式识别 · 计算机科学 2012-04-03 Stefan Bauer , Lutz-P. Nolte , Mauricio Reyes

Magnetic resonance imaging (MRI) has great potential to improve prostate cancer diagnosis. It can spare men with a normal exam from undergoing invasive biopsy while making biopsies more accurate in men with lesions suspicious for cancer.…

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang
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