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In experiments that study social phenomena, such as peer influence or herd immunity, the treatment of one unit may influence the outcomes of others. Such "interference between units" violates traditional approaches for causal inference, so…

统计方法学 · 统计学 2023-08-30 David Choi

The interplay of seasonality, the system's nonlinearities and intrinsic stochasticity is studied for a seasonally forced susceptible-exposed-infective-recovered stochastic model. The model is explored in the parameter region that…

生物物理 · 物理学 2010-10-19 Ganna Rozhnova , Ana Nunes

We develop methodology for causal inference in observational studies when using propensity score subclassification on data constructed with probabilistic record linkage techniques. We focus on scenarios where covariates and binary treatment…

统计方法学 · 统计学 2018-04-03 Joan Heck Wortman , Jerome P. Reiter

Interaction patterns at the individual level influence the behaviour of diffusion over contact networks. Most of the current diffusion models only consider direct interactions among individuals to build underlying infectious items…

社会与信息网络 · 计算机科学 2019-06-07 Md Shahzamal , Raja Jurdak , Bernard Mans , Frank de Hoog

The skin microbiome plays an important role in the maintenance of a healthy skin. It is an ecosystem, composed of several species, competing for resources and interacting with the skin cells. Imbalance in the cutaneous microbiome, also…

定量方法 · 定量生物学 2022-06-22 Eléa Thibault Greugny , Georgios N Stamatas , François Fages

We show how the nonlinear interaction effects `volume filling' and `adhesion' can be incorporated into the fractional subdiffusive transport of cells and individual organisms. To this end, we use microscopic random walk models with…

统计力学 · 物理学 2015-01-20 Peter Straka , Sergei Fedotov

High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

机器学习 · 统计学 2017-10-31 Dustin Tran , David M. Blei

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

应用统计 · 统计学 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

It is common to conduct causal inference in matched observational studies by proceeding as though treatment assignments within matched sets are assigned uniformly at random and using this distribution as the basis for inference. This…

统计方法学 · 统计学 2023-11-14 Samuel D. Pimentel , Yaxuan Huang

The associative interaction, such as hydrogen bonding, can bring about versatile functionalities to polymer systems, which has been investigated by tremendous researches, but the fundamental understanding on association process is still…

软凝聚态物质 · 物理学 2025-01-20 Xiangyu Zhang , Dong Meng

Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…

信息论 · 计算机科学 2021-01-29 Peter Adam Hoeher , Martin Damrath , Sunasheer Bhattacharjee , Max Schurwanz

Computational models of infectious disease can be broadly categorized into two types: individual-based (Agent-based), or compartmental models. While compartmental models can be structured to separate distinct sectors of a population, they…

种群与进化 · 定量生物学 2021-12-14 Cameron Zachreson , Sheryl Chang , Nathan Harding , Mikhail Prokopenko

The emergence of the phenomenon known as ABR (anti-bacterial resistance), is the result of the gradual decrease in the efficacy of antibiotics and the increase in the cost of producing new antibiotics. Hence, alternative solutions to…

种群与进化 · 定量生物学 2024-02-08 Nouf Alghamdi , Mal Horsburgh , Bakhtier Vasiev

We study the emergence of the collective spatio-temporal macroscopic properties of the immune system, by representing individually the elementary interactions between its microscopic components (antibodies, antigens, cytokines). The results…

适应与自组织系统 · 物理学 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun. R. Cohen

Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role. We have determined, by grazing incidence X-ray scattering, the…

We consider near-critical two-dimensional statistical systems at phase coexistence on the half plane with boundary conditions leading to the formation of a droplet separating coexisting phases. General low-energy properties of…

统计力学 · 物理学 2022-12-02 Alessio Squarcini , Antonio Tinti

Multi-category data arise in diverse fields including marketing, chemistry, public policy, genomics, political science, and ecology. We consider the problem of estimating ratios of category-specific means in a fully nonparametric setting,…

统计方法学 · 统计学 2025-10-29 Grant Hopkins , Sarah Teichman , Ellen Graham , Amy D Willis

Observational studies are a key resource for causal inference but are often affected by systematic biases. Prior work has focused mainly on detecting these biases, via sensitivity analyses and comparisons with randomized controlled trials,…

统计方法学 · 统计学 2025-06-03 Ilker Demirel , Zeshan Hussain , Piersilvio De Bartolomeis , David Sontag

Accurate interaction potentials between microscopic components such as colloidal particles or cells are crucial to understanding a range of processes, including colloidal crystallization, bacterial colony formation, and cancer metastasis.…