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The idea of "stratified medicine" is an important driver of methodological research on the identification of predictive biomarkers. Most methods proposed so far for this purpose have been developed for the use on randomized data only.…

统计方法学 · 统计学 2022-12-19 Julia Krzykalla , Axel Benner , Annette Kopp-Schneider

Simulated tempering is popular method of allowing MCMC algorithms to move between modes of a multimodal target density {\pi}. One problem with simulated tempering for multimodal targets is that the weights of the various modes change for…

统计计算 · 统计学 2019-02-12 Nicholas G. Tawn , Gareth O. Roberts , Jeffrey S. Rosenthal

In this work, we develop a novel Bayesian estimation method for the Dirichlet process (DP) mixture of the inverted Dirichlet distributions, which has been shown to be very flexible for modeling vectors with positive elements. The recently…

机器学习 · 计算机科学 2020-02-04 Zhanyu Ma , Yuping Lai

Negative Biased Temperature Instability (NBTI)-induced aging is one of the critical reliability threats in nano-scale devices. This paper makes the first attempt to study the NBTI aging in the on-chip weight memories of deep neural network…

硬件体系结构 · 计算机科学 2021-02-01 Muhammad Abdullah Hanif , Muhammad Shafique

The advancement of machine learning technologies has revolutionized the search and optimization of material properties. These algorithms often rely on theoretical calculations, such as density functional theory (DFT), for data inputs and…

材料科学 · 物理学 2024-11-06 Christopher Broyles , William Charles , Sheng Ran

A Discriminative Deep Forest (DisDF) as a metric learning algorithm is proposed in the paper. It is based on the Deep Forest or gcForest proposed by Zhou and Feng and can be viewed as a gcForest modification. The case of the fully…

机器学习 · 统计学 2017-05-29 Lev V. Utkin , Mikhail A. Ryabinin

Most machine learning classifiers only concern classification accuracy, while certain applications (such as medical diagnosis, meteorological forecasting, and computation advertising) require the model to predict the true probability, known…

机器学习 · 计算机科学 2025-03-13 Siguang Huang , Yunli Wang , Lili Mou , Huayue Zhang , Han Zhu , Chuan Yu , Bo Zheng

In deep multi-task learning, weights of task-specific networks are shared between tasks to improve performance on each single one. Since the question, which weights to share between layers, is difficult to answer, human-designed…

机器学习 · 计算机科学 2020-03-24 Jonas Prellberg , Oliver Kramer

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

Emerging evidence indicates that human cancers are intricately linked to human microbiomes, forming an inseparable connection. However, due to limited sample sizes and significant data loss during collection for various reasons, some…

基因组学 · 定量生物学 2024-08-16 Xinyuan Shi , Fangfang Zhu , Wenwen Min

Myocardial Infarction is a main cause of mortality globally, and accurate risk prediction is crucial for improving patient outcomes. Machine Learning techniques have shown promise in identifying high-risk patients and predicting outcomes.…

The paper presents a solution for the problem of choosing a method for analytical determining of weight factors for a genetic algorithm additive fitness function. This algorithm is the basis for an evolutionary process, which forms a stable…

神经与进化计算 · 计算机科学 2021-03-30 V. K. Ivanov , D. S. Dumina , N. A. Semenov

Bayesian deep learning approaches assume model parameters to be latent random variables and infer posterior distributions to quantify uncertainty, increase safety and trust, and prevent overconfident and unpredictable behavior. However,…

机器学习 · 计算机科学 2023-07-13 Jihao Andreas Lin , Joe Watson , Pascal Klink , Jan Peters

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression toward earlier and better patient-specific pathology management. However, conventional approaches rarely take advantage of…

We describe and analyze a broad class of mixture models for real-valued multivariate data in which the probability density of observations within each component of the model is represented as an arbitrary combination of basis functions.…

统计方法学 · 统计学 2025-02-28 M. E. J. Newman

The swift progression of machine learning (ML) has not gone unnoticed in the realm of statistical mechanics. ML techniques have attracted attention by the classical density-functional theory (DFT) community, as they enable discovery of…

Machine learning in high-stakes domains, such as healthcare, faces two critical challenges: (1) generalizing to diverse data distributions given limited training data while (2) maintaining interpretability. To address these challenges, we…

机器学习 · 计算机科学 2023-07-11 Keyan Nasseri , Chandan Singh , James Duncan , Aaron Kornblith , Bin Yu

Machine learning models used in medical applications often face challenges due to the covariate shift, which occurs when there are discrepancies between the distributions of training and target data. This can lead to decreased predictive…

机器学习 · 计算机科学 2024-12-24 Mingyang Cai , Thomas Klausch , Mark A. van de Wiel

Random Forest (Breiman, 2001) is a successful and widely used regression and classification algorithm. Part of its appeal and reason for its versatility is its (implicit) construction of a kernel-type weighting function on training data,…

机器学习 · 统计学 2022-10-13 Domagoj Ćevid , Loris Michel , Jeffrey Näf , Nicolai Meinshausen , Peter Bühlmann

In clinical trials, mixed effects models for repeated measures (MMRM) and pattern mixture models (PMM) are often used to analyze longitudinal continuous outcomes. We describe a simple missing data imputation algorithm for the MMRM that can…

统计方法学 · 统计学 2016-10-13 Yongqiang Tang