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Whole slide imaging provides a wide field-of-view (FOV) across cross-sections of biopsy or surgery samples, significantly facilitating pathological analysis and clinical diagnosis. Such high-quality images that enable detailed visualization…

光学 · 物理学 2024-07-31 Shi Zhao , Haowen Zhou , Siyu Lin , Ruizhi Cao , Changhuei Yang

A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…

光学 · 物理学 2025-06-24 Byung Gyu Chae

Adaptive optics (AO) has revolutionized imaging in {fields} from astronomy to microscopy by correcting optical aberrations. In label-free microscopes, however, conventional AO faces limitations due to the absence of guidestar and the need…

Advancements in high-throughput biomedical applications require real-time, large field-of-view (FOV) imaging. While current 2D lens-free imaging (LFI) systems improve FOV, they are often hindered by time-consuming multi-position…

Computational imaging methods empower modern microscopy with the ability of producing high-resolution, large field-of-view, aberration-free images. One of the dominant computational label-free imaging methods, Fourier ptychographic…

光学 · 物理学 2023-09-06 Ruizhi Cao , Cheng Shen , Changhuei Yang

We present a new pixelized method for the inversion of gravitationally lensed extended source images which we term adaptive semi-linear inversion (SLI). At the heart of the method is an h-means clustering algorithm which is used to derive a…

天体物理仪器与方法 · 物理学 2015-08-06 James Nightingale , Simon Dye

We report a compact, cost-effective and field-portable lensless imaging platform for quantitative microscopy. In this platform, the object is placed on top of an image sensor chip without using any lens. We use a low-cost galvo scanner to…

图像与视频处理 · 电气工程与系统科学 2019-04-26 He Zhang , Zichao Bian , Shaowei Jiang , Jian Liu , Pengming Song , Guoan Zheng

We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise…

光学 · 物理学 2015-06-19 W Glastre , O Hugon , O Jacquin , H Guillet de Chatellus , E Lacot

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…

医学物理 · 物理学 2020-10-21 Jules Scholler , Kassandra Groux , Kate Grieve , Claude Boccara , Pedro Mecê

White Light Imaging (WLI) and Narrow Band Imaging (NBI) are the two main colonoscopic modalities for polyp classification. While NBI, as optical chromoendoscopy, offers valuable vascular details, WLI remains the most common and often the…

计算机视觉与模式识别 · 计算机科学 2025-07-15 Qiang Hu , Qimei Wang , Jia Chen , Xuantao Ji , Mei Liu , Qiang Li , Zhiwei Wang

Here we present the Adaptive Optics Lucky Imager (AOLI), a state-of-the-art instrument which makes use of two well proved techniques, Lucky Imaging (LI) and Adaptive Optics (AO), to deliver diffraction limited imaging at visible…

Radial imaging techniques, such as projection-reconstruction (PR), are used in magnetic resonance imaging (MRI) for dynamic imaging, angiography, and short-imaging. They are robust to flow and motion, have diffuse aliasing patterns, and…

图像与视频处理 · 电气工程与系统科学 2021-01-13 Peder E. Z. Larson , Paul T. Gurney , Dwight G. Nishimura

Adaptive optics (AO) is a powerful image correction technique with proven benefits for many life-science microscopy methods. However, the complexity of adding a reflective wavefront modulator and a wavefront sensor into already complicated…

光学 · 物理学 2020-03-26 Pouya Rajaeipour , Alex Dorn , Kaustubh Banerjee , Hans Zappe , Çağlar Ataman

The Adaptive Optics Lucky Imager (AOLI) is a new instrument under development to demonstrate near diffraction limited imaging in the visible on large ground-based telescopes. We present the adaptive optics system being designed for the…

Recent advancements in large-scale visual-language pre-trained models have led to significant progress in zero-/few-shot anomaly detection within natural image domains. However, the substantial domain divergence between natural and medical…

计算机视觉与模式识别 · 计算机科学 2024-03-20 Chaoqin Huang , Aofan Jiang , Jinghao Feng , Ya Zhang , Xinchao Wang , Yanfeng Wang

The primary challenge in accelerating image super-resolution lies in reducing computation while maintaining performance and adaptability. Motivated by the observation that high-frequency regions (e.g., edges and textures) are most critical…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Wei Shang , Dongwei Ren , Wanying Zhang , Pengfei Zhu , Qinghua Hu , Wangmeng Zuo

AOLI (Adaptive Optics Lucky Imager) is a state-of-art instrument that combines adaptive optics (AO) and lucky imaging (LI) with the objective of obtaining diffraction limited images in visible wavelength at mid- and big-size ground-based…

We present a novel axial ptychographic coherent diffractive imaging (AP-CDI) technique designed to overcome the critical throughput bottleneck of conventional methods. By replacing the 2D raster scan with a simple 1D axial scan, our…

光学 · 物理学 2025-11-24 Qijun You , Lingshuo Meng , Fangrui Quan , Wei Cao

Astronomical telescopes suffer from a tradeoff between field of view (FoV) and image resolution: increasing the FoV leads to an optical field that is under-sampled by the science camera. This work presents a novel computational imaging…

天体物理仪器与方法 · 物理学 2025-08-07 Robin Swanson , Esther Y. H. Lin , Masen Lamb , Suresh Sivanandam , Kiriakos N. Kutulakos

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

图像与视频处理 · 电气工程与系统科学 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar
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