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One of the main applications of photoacoustic (PA) imaging is the recovery of functional tissue properties, such as blood oxygenation (sO2). This is typically achieved by linear spectral unmixing of relevant chromophores from multispectral…

医学物理 · 物理学 2022-04-19 Janek Gröhl , Thomas Kirchner , Tim Adler , Lena Maier-Hein

Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties up to several centimeters deep in tissue, creating the potential for numerous exciting clinical…

医学物理 · 物理学 2021-04-15 Janek Gröhl , Melanie Schellenberg , Kris Dreher , Lena Maier-Hein

Accurate measurement of optical absorption coefficients from photoacoustic imaging (PAI) data would enable direct mapping of molecular concentrations, providing vital clinical insight. The ill-posed nature of the problem of absorption…

图像与视频处理 · 电气工程与系统科学 2023-06-13 Janek Gröhl , Thomas R. Else , Lina Hacker , Ellie V. Bunce , Paul W. Sweeney , Sarah E. Bohndiek

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

光学 · 物理学 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar

Recent advances in photoacoustic (PA) imaging have enabled detailed images of microvascular structure and quantitative measurement of blood oxygenation or perfusion. Standard reconstruction methods for PA imaging are based on solving an…

信号处理 · 电气工程与系统科学 2020-04-17 MinWoo Kim , Geng-Shi Jeng , Ivan Pelivanov , Matthew O'Donnell

Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…

光学 · 物理学 2026-01-29 Daohuai Jiang , Xuanxuan Ye , Hengrong Lan , Xianzeng Zhang , Fei Gao

Recently we demonstrated an integrated photoacoustic (PA) and ultrasound (PAUS) system using a kHz-rate wavelength-tunable laser and a swept-beam delivery approach. It irradiates a medium using a narrow laser beam sweeping at high…

信号处理 · 电气工程与系统科学 2020-01-28 MinWoo Kim , Geng-Shi Jeng , Matthew O'Donnell , Ivan Pelivanov

Significance: Quantitative measurement of blood oxygen saturation (sO$_2$) with photoacoustic (PA) imaging is one of the most sought after goals of quantitative PA imaging research due to its wide range of biomedical applications. Aim: A…

医学物理 · 物理学 2021-02-23 Thomas Kirchner , Martin Frenz

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

图像与视频处理 · 电气工程与系统科学 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Photoacoustic imaging (PAI) is a novel medical imaging modality that uses the advantages of the spatial resolution of ultrasound imaging and the high contrast of pure optical imaging. Analytical algorithms are usually employed to…

信号处理 · 电气工程与系统科学 2018-02-27 Moein Mozaffarzadeh , Ali Mahloojifar , Mohammadreza Nasiriavanaki , Mahdi Orooji

Photo-acoustic tomography is a coupled-physics (hybrid) medical imaging modality that aims to reconstruct optical parameters in biological tissues from ultrasound measurements. As propagating light gets partially absorbed, the resulting…

偏微分方程分析 · 数学 2020-01-08 Guillaume Bal , Adrian Kirkeby

Photoacoustic imaging (PAI) is a promising approach to realize in vivo transcranial cerebral vascular imaging. However, the strong attenuation and distortion of the photoacoustic wave caused by the thick porous skull greatly affect the…

医学物理 · 物理学 2022-08-16 Ya Gao , Wenyi Xu , Yiming Chen , Weiya Xie , Qian Cheng

Photoacoustic imaging (PAI) is a novel modality in biomedical imaging technology that combines the rich optical contrast with the deep penetration of ultrasound. To date, PAI technology has found applications in various biomedical fields.…

医学物理 · 物理学 2023-09-07 Daohuai Jiang , Luyao Zhu , Shangqing Tong , Yuting Shen , Feng Gao , Fei Gao

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

医学物理 · 物理学 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…

Photoacoustic imaging (PAI) is an emerging non-invasive imaging modality combining the advantages of deep ultrasound penetration and high optical contrast. Image reconstruction is an essential topic in PAI, which is unfortunately an…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Hengrong Lan , Daohuai Jiang , Changchun Yang , Fei Gao

Photoacoustic(PA) imaging is a non-destructive and non-invasive technology for visualizing minute blood vessel structures in the body using ultrasonic sensors. In PA imaging, the image quality of a single-shot image is poor, and it is…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Tatsuhiro Eguchi , Shumpei Takezaki , Mihoko Shimano , Takayuki Yagi , Ryoma Bise
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