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Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

人工智能 · 计算机科学 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

Identifying causal relations among multi-variate time series is one of the most important elements towards understanding the complex mechanisms underlying the dynamic system. It provides critical tools for forecasting, simulations and…

机器学习 · 计算机科学 2023-02-22 Yang Sun , Yifan Xie

Deep Q Networks (DQN) have shown remarkable success in various reinforcement learning tasks. However, their reliance on associative learning often leads to the acquisition of spurious correlations, hindering their problem-solving…

人工智能 · 计算机科学 2025-10-28 Elouanes Khelifi , Amir Saki , Usef Faghihi

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

神经元与认知 · 定量生物学 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

We introduce a novel kernel that models input-dependent couplings across multiple latent processes. The pairwise joint kernel measures covariance along inputs and across different latent signals in a mutually-dependent fashion. A latent…

机器学习 · 统计学 2017-10-04 Sami Remes , Markus Heinonen , Samuel Kaski

Kernel methods are powerful machine learning techniques which implement generic non-linear functions to solve complex tasks in a simple way. They Have a solid mathematical background and exhibit excellent performance in practice. However,…

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

神经元与认知 · 定量生物学 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

神经元与认知 · 定量生物学 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

机器学习 · 统计学 2019-09-11 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

机器学习 · 统计学 2018-09-19 Ioan Gabriel Bucur , Tom van Bussel , Tom Claassen , Tom Heskes

Graph neural networks (GNNs) have been developed to model the relationship between regions of interest (ROIs) in brains and have shown significant improvement in detecting brain diseases. However, most of these frameworks do not consider…

机器学习 · 计算机科学 2025-06-23 Falih Gozi Febrinanto , Adonia Simango , Chengpei Xu , Jingjing Zhou , Jiangang Ma , Sonika Tyagi , Feng Xia

In decision-making systems, it is important to have classifiers that have calibrated uncertainties, with an optimisation objective that can be used for automated model selection and training. Gaussian processes (GPs) provide uncertainty…

机器学习 · 统计学 2020-03-05 Vincent Dutordoir , Mark van der Wilk , Artem Artemev , James Hensman

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

应用统计 · 统计学 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

机器学习 · 统计学 2017-10-31 Dustin Tran , David M. Blei

In this study, a scalable online kernel learning framework is proposed for estimating bidirectional causal effects in systems characterized by mutual dependence and heteroskedasticity. Traditional causal inference often focuses on…

机器学习 · 统计学 2025-11-24 Masahiro Tanaka

Graph collaborative filtering (GCF) has gained considerable attention in recommendation systems by leveraging graph learning techniques to enhance collaborative filtering (CF). One classical approach in GCF is to learn user and item…

信息检索 · 计算机科学 2024-04-09 Xiangmeng Wang , Qian Li , Dianer Yu , Wei Huang , Guandong Xu

Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-protein interactions, etc. A common setting involves inferring network edges…

定量方法 · 定量生物学 2007-05-23 Jean-Philippe Vert , Jian Qiu , William Stafford Noble

The notion of causality assumes a paramount position within the realm of human cognition. Over the past few decades, there has been significant advancement in the domain of causal effect estimation across various disciplines, including but…

机器学习 · 统计学 2024-05-24 Zongyu Li , Xiaobo Guo , Siwei Qiang

The paper reviews methods that seek to draw causal inference from observational data and demonstrates how they can be applied to empirical problems in engineering research. It presents a framework for causal identification based on the…

应用统计 · 统计学 2022-11-28 Daniel J Graham

We propose estimators based on kernel ridge regression for nonparametric causal functions such as dose, heterogeneous, and incremental response curves. Treatment and covariates may be discrete or continuous in general spaces. Due to a…

计量经济学 · 经济学 2022-10-25 Rahul Singh , Liyuan Xu , Arthur Gretton