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Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

医学物理 · 物理学 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

This study experimentally examines the impact of spacing between two pulsed jets and their strengths on the fluid dynamics within an elastic hemispherical cavity. Such interactions between multiple pulsed jets are observed in various…

流体动力学 · 物理学 2026-05-22 L. S. Merlo , L. Kadem , W. Saleh , H. D. Ng , G. Di Labbio

This paper presents a novel methodology for the direct numerical modeling and simulation of turbulent flows. The kinetic model equation is firstly extended to turbulent flow with the account of coupled evolution of kinetic, thermal, and…

计算物理 · 物理学 2025-03-11 Xiaojian Yang , Kun Xu

In the framework of accurate and efficient segregated schemes for 3D cardiac electromechanics and 0D cardiovascular models, we propose here a novel numerical approach to address the coupled 3D-0D problem introduced in Part I of this…

We present a two dimensional model describing the elastic behaviour of the wall of a curved blood vessel. The wall has a laminate structure consisting of several anisotropic layers of varying thickness and is assumed to be much smaller in…

组织与器官 · 定量生物学 2017-08-18 Arpan Ghosh , Vladimir Kozlov , Sergey Nazarov , David Rule

Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart valves have not formed…

组织与器官 · 定量生物学 2018-09-19 Nicholas A. Battista , Andrea N. Lane , Laura A. Miller

Cardiovascular monitoring is important to prevent diseases from progressing. The jugular venous pulse (JVP) waveform offers important clinical information about cardiac health, but is not routinely examined due to its invasive…

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

医学物理 · 物理学 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right…

Virtual interventions enable the physics-based simulation of device deployment within coronary arteries. This framework allows for counterfactual reasoning by deploying the same device in different arterial anatomies. However, current…

图像与视频处理 · 电气工程与系统科学 2025-11-26 Karim Kadry , Shreya Gupta , Jonas Sogbadji , Michiel Schaap , Kersten Petersen , Takuya Mizukami , Carlos Collet , Farhad R. Nezami , Elazer R. Edelman

We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law…

Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…

机器学习 · 计算机科学 2026-04-09 Giulia Bertaglia , Raffaella Fiamma Cabini

$\textbf{Purpose:}$ To develop a new method for free-breathing 3D extracellular volume (ECV) mapping of the whole heart at 3T. $\textbf{Methods:}$ A free-breathing 3D cardiac ECV mapping method was developed at 3T. T1 mapping was performed…

Unlike Right Atrium (RA), Left Atrium (LA) presents distinctive challenges, including much thinner myocardial walls, complex and irregular morphology, as well as diversity in individual's structure, making off-the-shelf methods designed for…

图像与视频处理 · 电气工程与系统科学 2024-05-29 Abdul Qayyum , Moona Mazher , Angela Lee , Jose A Solis-Lemus , Imran Razzak , Steven A Niederer

Embolization, stroke, ischaemic lesion, and perforation remain significant concerns in endovascular interventions. Intravascular sensing of tool interaction with the arteries is advantageous to minimize such complications and enhance…

机器人学 · 计算机科学 2021-02-16 Masoud Razban , Javad Dargahi , Benoit Boulet

Background. Despite the routine prescription of rate control therapy for atrial fibrillation (AF), clinical evidence demonstrating a heart rate target is lacking. Aim of the present study was to run a mathematical model simulating AF…

Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…

图像与视频处理 · 电气工程与系统科学 2023-08-21 Xiaoxiao He , Chaowei Tan , Ligong Han , Bo Liu , Leon Axel , Kang Li , Dimitris N. Metaxas

An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in…

流体动力学 · 物理学 2018-07-05 Qianhui Li , Christoph H. Bruecker

Mathematical models of cardiac electrical activity are one of the most important tools for elucidating information about the heart diagnostic. Even though it is one of the major problems in biomedical research, an efficient mathematical…

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