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Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Mathematical modeling offers a valuable approach to understanding Alzheimers disease (AD) given its complexity, unknown causes, and lack of effective treatments. Models, once validated, offer a powerful tool to test medical hypotheses that…

偏微分方程分析 · 数学 2026-03-20 G. Landi , A. Scaravelli , M. C. Tesi , C. Testa

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

People are living longer than ever before, and with this arises new complications and challenges for humanity. Among the most pressing of these challenges is of understanding the role of aging in the development of dementia. This paper is…

统计方法学 · 统计学 2018-08-07 Jonathan P Williams , Curtis B Storlie , Terry M Therneau , Clifford R Jack , Jan Hannig

Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…

Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…

计算与语言 · 计算机科学 2021-09-27 Akshay Valsaraj , Ithihas Madala , Nikhil Garg , Veeky Baths

Hidden Markov models (HMMs) are commonly used for disease progression modeling when the true patient health state is not fully known. Since HMMs typically have multiple local optima, incorporating additional patient covariates can improve…

机器学习 · 统计学 2021-10-05 Matt Baucum , Anahita Khojandi , Theodore Papamarkou

Reliability in Neural Networks (NNs) is crucial in safety-critical applications like healthcare, and uncertainty estimation is a widely researched method to highlight the confidence of NNs in deployment. In this work, we propose an…

机器学习 · 计算机科学 2020-11-20 Utkarsh Sarawgi , Wazeer Zulfikar , Rishab Khincha , Pattie Maes

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Lilia Lazli

Energy-based models (EBMs) provide a powerful and flexible way of learning a joint probability distribution over data by constructing an energy surface. This energy surface enables insight extraction and conditional sampling. We apply EBMs…

等离子体物理 · 物理学 2026-05-12 Phil Travis , Troy Carter

Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

机器学习 · 计算机科学 2023-11-06 Md Gulzar Hussain , Ye Shiren

Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions worldwide. In the absence of effective treatment options, early diagnosis is crucial for initiating management strategies to delay disease onset and slow down…

机器学习 · 计算机科学 2025-07-08 Saeed Jamshidiha , Alireza Rezaee , Farshid Hajati , Mojtaba Golzan , Raymond Chiong

Objective: Finding events of interest is a common task in biomedical signal processing. The detection of epileptic seizures and signal artefacts are two key examples. Epoch-based classification is the typical machine learning framework to…

信号处理 · 电气工程与系统科学 2023-07-10 Nick Seeuws , Maarten De Vos , Alexander Bertrand

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

神经元与认知 · 定量生物学 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Early diagnosis and discovery of therapeutic drug targets are crucial objectives for effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely…

机器学习 · 计算机科学 2026-05-01 Maryam Khalid , Fadeel Sher Khan , John Broussard , Arko Barman

We present a new method of training energy-based models (EBMs) for anomaly detection that leverages low-dimensional structures within data. The proposed algorithm, Manifold Projection-Diffusion Recovery (MPDR), first perturbs a data point…

机器学习 · 计算机科学 2023-10-31 Sangwoong Yoon , Young-Uk Jin , Yung-Kyun Noh , Frank C. Park

Computational models of neurodegeneration aim to emulate the evolving pattern of pathology in the brain during neurodegenerative disease, such as Alzheimer's disease. Previous studies have made specific choices on the mechanisms of…

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Existing research has shown the potential of classifying Alzheimers Disease (AD) from eye-tracking (ET) data with classifiers that rely on task-specific engineered features. In this paper, we investigate whether we can improve on existing…

计算机视觉与模式识别 · 计算机科学 2023-09-25 Harshinee Sriram , Cristina Conati , Thalia Field

Disease progression modeling (DPM) using longitudinal data is a challenging task in machine learning for healthcare that can provide clinicians with better tools for diagnosis and monitoring of disease. Existing DPM algorithms neglect…

计算机视觉与模式识别 · 计算机科学 2018-08-17 Mostafa Mehdipour Ghazi , Mads Nielsen , Akshay Pai , M. Jorge Cardoso , Marc Modat , Sebastien Ourselin , Lauge Sørensen