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With the accumulation of data at an unprecedented rate, its potential to fuel scientific discovery is growing exponentially. This position paper urges the Machine Learning (ML) community to exploit the capabilities of large generative…

Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

定量方法 · 定量生物学 2009-02-19 Claude Pasquier

Generative Artificial Intelligence (GenAI), particularly Large Language Models (LLMs), offer powerful capabilities for interpreting the complex data landscape in healthcare. In this paper, we present a comprehensive overview of the…

Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

分布式、并行与集群计算 · 计算机科学 2023-06-08 Alessandro Margara , Gianpaolo Cugola , Nicolò Felicioni , Stefano Cilloni

The continuous increase of data generated provides enormous possibilities of both public and private companies. The management of this mass of data or big data will play a crucial role in the society of the future, as it finds applications…

计算机与社会 · 计算机科学 2015-01-15 Fatima El Jamiy , Abderrahmane Daif , Mohamed Azouazi , Abdelaziz Marzak

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

While manufacturers have been generating highly distributed data from various systems, devices and applications, a number of challenges in both data management and data analysis require new approaches to support the big data era. These…

数据库 · 计算机科学 2018-12-14 JunPing Wang , WenSheng Zhang , YouKang Shi , ShiHui Duan , Jin Liu

The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

物理与社会 · 物理学 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

Distributed approaches based on the map-reduce programming paradigm have started to be proposed in the bioinformatics domain, due to the large amount of data produced by the next-generation sequencing techniques. However, the use of…

分布式、并行与集群计算 · 计算机科学 2018-07-05 Umberto Ferraro Petrillo , Mara Sorella , Giuseppe Cattaneo , Raffaele Giancarlo , Simona Rombo

Deep learning (DL) along with never-ending advancements in computational processing and cloud technologies have bestowed us powerful analyzing tools and techniques in the past decade and enabled us to use and apply them in various fields of…

机器学习 · 计算机科学 2023-02-23 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , Khaled M. Rasheed , Hamid R. Arabnia

In systems biology, it is becoming increasingly common to measure biochemical entities at different levels of the same biological system. Hence, data fusion problems are abundant in the life sciences. With the availability of a multitude of…

Big Data is the most popular emerging trends that becomes a blessing for human kinds and it is the necessity of day-to-day life. For example, Facebook. Every person involves with producing data either directly or indirectly. Thus, Big Data…

数据库 · 计算机科学 2019-03-18 Ripon Patgiri , Sabuzima Nayak , Samir Kumar Borgohain

The success of deep learning is largely due to the availability of large amounts of training data that cover a wide range of examples of a particular concept or meaning. In the field of medicine, having a diverse set of training data on a…

人工智能 · 计算机科学 2023-05-02 Edward Y. Chang

With the continuous advancement of technology, artificial intelligence has significantly impacted various fields, particularly healthcare. Generative models, a key AI technology, have revolutionized medical image generation, data analysis,…

机器学习 · 计算机科学 2024-10-10 Yuan Sun , Jorge Ortiz

High-throughput sequencing (HTS) is revolutionizing biological research by enabling scientists to quickly and cheaply query variation at a genomic scale. Despite the increasing ease of obtaining such data, using these data effectively still…

基因组学 · 定量生物学 2012-11-09 Sonal Singhal

The vision of IASIS project is to turn the wave of big biomedical data heading our way into actionable knowledge for decision makers. This is achieved by integrating data from disparate sources, including genomics, electronic health records…

Deep neural network-based architectures give promising results in various domains including pattern recognition. Finding the optimal combination of the hyper-parameters of such a large-sized architecture is tedious and requires a large…

计算机视觉与模式识别 · 计算机科学 2020-03-17 Animesh Singh , Sandip Saha , Ritesh Sarkhel , Mahantapas Kundu , Mita Nasipuri , Nibaran Das

Motivation: Gene regulatory interactions are of fundamental importance to various biological functions and processes. However, only a few previous computational studies have claimed success in revealing genome-wide regulatory landscapes…

分子网络 · 定量生物学 2017-02-09 Shupeng Gui , Rui Chen , Liang Wu , Ji Liu , Hongyu Miao

A major goal in genomics is to properly capture the complex dynamical behaviors of gene regulatory networks (GRNs). This includes inferring the complex interactions between genes, which can be used for a wide range of genomics analyses,…

分子网络 · 定量生物学 2023-01-18 Mohammad Alali , Mahdi Imani

Recent advances in machine learning have made revolutionary breakthroughs in computer games, image and natural language understanding, and scientific discovery. Foundation models and large-scale language models (LLMs) have recently achieved…

神经元与认知 · 定量生物学 2023-10-31 Ran Wang , Zhe Sage Chen