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In this paper, we consider a pressure-velocity formulation of the heterogeneous wave equation and employ the constraint energy minimizing generalized multiscale finite element method (CEM-GMsFEM) to solve this problem. The proposed method…

数值分析 · 数学 2020-10-06 Eric Chung , Sai-Mang Pun

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

机器学习 · 计算机科学 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu

We present COmpetitive Mechanisms for Efficient Transfer (COMET), a modular world model which leverages reusable, independent mechanisms across different environments. COMET is trained on multiple environments with varying dynamics via a…

机器学习 · 计算机科学 2024-04-24 Anson Lei , Frederik Nolte , Bernhard Schölkopf , Ingmar Posner

Popular statistical software provides Bayesian information criterion (BIC) for multilevel models or linear mixed models. However, it has been observed that the combination of statistical literature and software documentation has led to…

统计方法学 · 统计学 2022-06-24 Sun-Joo Cho , Hao Wu , Matthew Naveiras

Recent advancements in recommender systems have focused on leveraging Large Language Models (LLMs) to improve user preference modeling, yielding promising outcomes. However, current LLM-based approaches struggle to fully leverage user…

信息检索 · 计算机科学 2024-10-31 Yang Zhang , Juntao You , Yimeng Bai , Jizhi Zhang , Keqin Bao , Wenjie Wang , Tat-Seng Chua

Scientists regularly pose questions about treatment effects on outcomes conditional on a post-treatment event. However, causal inference in such settings requires care, even in perfectly executed randomized experiments. Recently, the…

统计方法学 · 统计学 2026-02-19 Chan Park , Mats Stensrud , Eric Tchetgen Tchetgen

We consider the task of discovering gene regulatory networks, which are defined as sets of genes and the corresponding transcription factors which regulate their expression levels. This can be viewed as a variable selection problem,…

统计方法学 · 统计学 2014-12-04 Justin Bleich , Adam Kapelner , Edward I. George , Shane T. Jensen

The conditional moment problem is a powerful formulation for describing structural causal parameters in terms of observables, a prominent example being instrumental variable regression. A standard approach reduces the problem to a finite…

机器学习 · 计算机科学 2023-03-24 Andrew Bennett , Nathan Kallus

Small-molecule drug discovery requires simultaneous optimization of numerous properties of candidate molecules. These properties can be investigated through the analysis of high-dimensional biological signatures, such as cell morphology and…

机器学习 · 计算机科学 2026-05-28 Łukasz Janisiów , Sebastian Musiał , Bartosz Zieliński , Dawid Rymarczyk , Tomasz Danel

Bilinear Matrix Inequalities (BMIs) are fundamental to control system design but are notoriously difficult to solve due to their nonconvexity. This study addresses BMI-based control optimization problems by adapting and integrating advanced…

系统与控制 · 电气工程与系统科学 2026-01-14 Syue-Cian Lin , Wei-Yu Chiu , Chien-Feng Wu

The growing demand for personalized decision-making has led to a surge of interest in estimating the Conditional Average Treatment Effect (CATE). Various types of CATE estimators have been developed with advancements in machine learning and…

机器学习 · 计算机科学 2024-11-04 Yiyan Huang , Cheuk Hang Leung , Siyi Wang , Yijun Li , Qi Wu

The coupling effects in multiphysics processes are often neglected in designing multiscale methods. The coupling may be described by a non-positive definite operator, which in turn brings significant challenges in multiscale simulations. In…

数值分析 · 数学 2024-01-05 Xiaofei Guan , Lijian Jiang , Yajun Wang

Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…

机器学习 · 计算机科学 2020-04-24 Will Y. Zou , Smitha Shyam , Michael Mui , Mingshi Wang , Jan Pedersen , Zoubin Ghahramani

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

统计方法学 · 统计学 2025-12-03 Ruoqi Yu , Peng Ding

We study off-policy evaluation (OPE) of contextual bandit policies for large discrete action spaces where conventional importance-weighting approaches suffer from excessive variance. To circumvent this variance issue, we propose a new…

机器学习 · 统计学 2023-06-12 Yuta Saito , Qingyang Ren , Thorsten Joachims

This study proposes a novel framework based on the RuleFit method to estimate Heterogeneous Treatment Effect (HTE) in a randomized clinical trial. To achieve this, we adopted S-learner of the metaalgorithm for our proposed framework. The…

统计方法学 · 统计学 2023-07-28 Mayu Hiraishi , Ke Wan , Kensuke Tanioka , Hiroshi Yadohisa , Toshio Shimokawa

Optimal treatment regimes are personalized policies for making a treatment decision based on subject characteristics, with the policy chosen to maximize some value. It is common to aim to maximize the mean outcome in the population, via a…

统计方法学 · 统计学 2022-02-28 Liu Leqi , Edward H. Kennedy

Although deep learning has achieved appealing results on several machine learning tasks, most of the models are deterministic at inference, limiting their application to single-modal settings. We propose a novel general-purpose framework…

机器学习 · 计算机科学 2020-10-12 Sameera Ramasinghe , Kanchana Ranasinghe , Salman Khan , Nick Barnes , Stephen Gould

CTR prediction has been widely used in the real world. Many methods model feature interaction to improve their performance. However, most methods only learn a fixed representation for each feature without considering the varying importance…

信息检索 · 计算机科学 2022-12-02 Fangye Wang , Yingxu Wang , Dongsheng Li , Hansu Gu , Tun Lu , Peng Zhang , Ning Gu

Linear Mixed-Effects (LME) models are a fundamental tool for modeling correlated data, including cohort studies, longitudinal data analysis, and meta-analysis. Design and analysis of variable selection methods for LMEs is more difficult…

统计方法学 · 统计学 2022-05-17 Aleksei Sholokhov , James V. Burke , Damian F. Santomauro , Peng Zheng , Aleksandr Aravkin