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In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

定量方法 · 定量生物学 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

We propose a new estimator for heterogeneous treatment effects in a partially linear model (PLM) with multiple exogenous covariates and a potentially endogenous treatment variable. Our approach integrates a Robinson transformation to handle…

计量经济学 · 经济学 2024-10-04 Xiaolin Sun

The Kaplan-Meier estimate, also known as the product-limit method (PLM), is a widely used non-parametric maximum likelihood estimator (MLE) in survival analysis. In the context of highway engineering, it has been repeatedly applied to…

应用统计 · 统计学 2026-03-02 Igor Mikolášek

Unlike the ordinary least-squares (OLS) estimator for the linear model, a ridge regression linear model provides coefficient estimates via shrinkage, usually with improved mean-square and prediction error. This is true especially when the…

统计方法学 · 统计学 2015-06-25 George Karabatsos

In this paper we consider functional data with heterogeneity in time and in population. We propose a mixture model with segmentation of time to represent this heterogeneity while keeping the functional structure. Maximum likelihood…

统计方法学 · 统计学 2024-07-24 Vincent Brault , Émilie Devijver , Charlotte Laclau

In this paper, we propose a data-adaptive empirical likelihood-based approach for treatment effect estimation and inference, which overcomes the obstacle of the traditional empirical likelihood-based approaches in the high-dimensional…

统计方法学 · 统计学 2020-12-15 Wei Liang , Ying Yan

Stochastic compartmental models are prevalent tools for describing disease spread, but inference under these models is challenging for many types of surveillance data when the marginal likelihood function becomes intractable due to missing…

统计方法学 · 统计学 2026-02-05 Suchismita Roy , Alexander A. Fisher , Jason Xu

Public charging station occupancy prediction plays key importance in developing a smart charging strategy to reduce electric vehicle (EV) operator and user inconvenience. However, existing studies are mainly based on conventional…

机器学习 · 计算机科学 2021-11-16 Tai-Yu Ma , Sébastien Faye

This book handles the fatty liver disease from the bio-statistical point of view . It discusses the disease process in the simple general form of health-disease-death multi-states model . Continuous Time Markov Chains are used to estimate…

其他定量生物学 · 定量生物学 2021-11-16 Iman Mohammed Attia Ebd-Elkhalik Abo-Elreesh

We study empirical Bayes (EB) predictive density estimation in linear mixed models (LMMs) with large number of units, which induce a high dimensional random effects space. Focusing on Kullback Leibler (KL) risk minimization, we develop a…

统计方法学 · 统计学 2026-03-31 Abir Sarkar , Gourab Mukherjee , Keisuke Yano

We consider distributed estimation of the inverse covariance matrix, also called the concentration or precision matrix, in Gaussian graphical models. Traditional centralized estimation often requires global inference of the covariance…

机器学习 · 统计学 2015-06-15 Zhaoshi Meng , Dennis Wei , Ami Wiesel , Alfred O. Hero

Joint modelling of longitudinal and time-to-event data is usually described by a joint model which uses shared or correlated latent effects to capture associations between the two processes. Under this framework, the joint distribution of…

统计方法学 · 统计学 2022-03-07 Zili Zhang , Christiana Charalambous , Peter Foster

Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the…

统计方法学 · 统计学 2019-02-20 Martina McMenamin , Jessica K. Barrett , Anna Berglind , James M. S. Wason

Linear regression and classification methods with repeated functional data are considered. For each statistical unit in the sample, a real-valued parameter is observed over time under different conditions related by some neighborhood…

统计方法学 · 统计学 2024-09-23 Issam-Ali Moindjié , Cristian Preda , Sophie Dabo-Niang

We describe a Bayesian approach to estimating luminosity functions. We derive the likelihood function and posterior probability distribution for the luminosity function, given the observed data, and we compare the Bayesian approach with…

天体物理学 · 物理学 2009-11-13 Brandon C. Kelly , Xiaohui Fan , Marianne Vestergaard

In Wang-Landau type algorithms, Monte-Carlo updates are performed with respect to the density of states, which is iteratively refined during simulations. The partition function and thermodynamic observables are then obtained by standard…

高能物理 - 格点 · 物理学 2015-09-29 Kurt Langfeld , Biagio Lucini , Roberto Pellegrini , Antonio Rago

The adoption of the Prospective Payment System (PPS) in the UK National Health Service (NHS) has led to the creation of patient groups called Health Resource Groups (HRG). HRGs aim to identify groups of clinically similar patients that…

计算机与社会 · 计算机科学 2021-07-02 Chimdimma Noelyn Onah , Richard Allmendinger , Julia Handl , Ken W. Dunn

Health economic evaluations based on patient-level data collected alongside clinical trials~(e.g. health related quality of life and resource use measures) are an important component of the process which informs resource allocation…

应用统计 · 统计学 2020-05-25 Andrea Gabrio , Rachael Hunter , Alexina J. Mason , Gianluca Baio

This paper develops the likelihood ratio-based test of the null hypothesis of a M0-component model against an alternative of (M0 + 1)-component model in the normal mixture panel regression by extending the Expectation-Maximization (EM) test…

计量经济学 · 经济学 2023-06-06 Yu Hao , Hiroyuki Kasahara

Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and…

机器学习 · 计算机科学 2022-06-09 Pierluigi Costanzo , Kalia Orphanou