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Background. Despite the routine prescription of rate control therapy for atrial fibrillation (AF), clinical evidence demonstrating a heart rate target is lacking. Aim of the present study was to run a mathematical model simulating AF…

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Heart rate variability (HRV), defined as the variability between consecutive heartbeats, is a surrogate measure of cardiac vagal tone. It is widely accepted that a decreased HRV is associated to several risk factors and cardiovascular…

医学物理 · 物理学 2021-05-20 Stefania Scarsoglio , Luca Ridolfi

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Atrial fibrillation (AF) is the most common form of arrhythmia with accelerated and irregular heart rate (HR), leading to both heart failure and stroke and being responsible for an increase in cardiovascular morbidity and mortality. In…

流体动力学 · 物理学 2018-06-26 Stefania Scarsoglio , Caterina Gallo , Luca Ridolfi

Physical exercise has significant benefits for humans in improving the health and quality of their lives, by improving the functional performance of their cardiovascular and respiratory systems. However, it is very important to control the…

定量方法 · 定量生物学 2014-03-28 Dur-e-Zehra Baig

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Fluctuations of the human heart beat constitute a complex system that has been studied mostly under resting conditions using conventional time series analysis methods. During physical exercise, the variability of the fluctuations is…

数据分析、统计与概率 · 物理学 2020-08-13 Matti Molkkari , Giorgio Angelotti , Thorsten Emig , Esa Räsänen

We study the heartbeat activity of healthy individuals at rest and during exercise. We focus on correlation properties of the intervals formed by successive peaks in the pulse wave and find significant scaling differences between rest and…

There has recently been growing evidence that atrial fibrillation (AF), the most common cardiac arrhythmia, is independently associated with the risk of dementia. This represents a very recent frontier with high social impact for the number…

流体动力学 · 物理学 2017-05-10 Stefania Scarsoglio , Andrea Saglietto , Matteo Anselmino , Fiorenzo Gaita , Luca Ridolfi

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

流体动力学 · 物理学 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni

Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and…

医学物理 · 物理学 2014-09-12 Stefania Scarsoglio , Andrea Guala , Carlo Camporeale , Luca Ridolfi

Heart rate recovery (HRR) within the initial minute following exercise is a widely utilized metric for assessing cardiac autonomic function in individuals and predicting mortality risk in patients with cardiovascular disease. However,…

信号处理 · 电气工程与系统科学 2025-03-31 Ziheng Mao , Yuan He , Jia Zhang , Yimiao Sun , Yadong Xie , Xiuzhen Guo

Heart rate variability (HRV) indices describe properties of interbeat intervals in electrocardiogram (ECG). Usually HRV is measured exclusively in normal sinus rhythm (NSR) excluding any form of paroxysmal rhythm. Atrial fibrillation (AF)…

应用统计 · 统计学 2023-08-28 Nikita Markov , Ilya Kotov , Konstantin Ushenin , Yakov Bozhko

Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF…

Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…

生物物理 · 物理学 2025-11-04 Artemii Remizov , Sergey Lapin

The technological advancement in wireless health monitoring through the direct contact of the skin allows the development of light-weight wrist-worn wearable devices to be equipped with different sensors such as photoplethysmography (PPG)…

Atrial fibrillation (AF) consequences on the heart valve dynamics are usually studied along with a valvular disfunction or disease, since in medical monitoring the two pathologies are often concomitant. Aim of the present work is to study,…

流体动力学 · 物理学 2015-10-27 Stefania Scarsoglio , Carlo Camporeale , Andrea Guala , Luca Ridolfi

A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…

数据分析、统计与概率 · 物理学 2017-09-27 Stefania Scarsoglio , Fabio Cazzato , Luca Ridolfi

Cardiovascular diseases are best diagnosed using multiple modalities that assess both the heart's electrical and mechanical functions. While effective, imaging techniques like echocardiography and nuclear imaging are costly and not widely…

医学物理 · 物理学 2024-10-28 Sajjad Karimi , Shirin Karimi , Amit J. Shah , Gari D. Clifford , Reza Sameni
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