相关论文: Beyond NGS data sharing and towards open science

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

Next-generation sequencing (NGS) is a pivotal technique in genome sequencing due to its high throughput, rapid results, cost-effectiveness, and enhanced accuracy. Its significance extends across various domains, playing a crucial role in…

Scientific datasets and analysis pipelines are increasingly being shared publicly in the interest of open science. However, mechanisms are lacking to reliably identify which pipelines and datasets can appropriately be used together. Given…

Data is a valuable asset, and sharing it as a product across organizations is key to building comprehensive and useful insights in fields such as science and industry. Before sharing, data often requires transformation to comply with…

Processing high-throughput DNA sequencing data of individuals or populations requires stringing together independent software tools with many parameters, often leading to non-reproducible pipelines and datasets. We developed grenepipe to…

Building high-quality knowledge graphs (KGs) from diverse sources requires combining methods for information extraction, data transformation, ontology mapping, entity matching, and data fusion. Numerous methods and tools exist for each of…

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

We develop a tool called PipeGen for efficient data transfer between database management systems (DBMSs). PipeGen targets data analytics workloads on shared-nothing engines. It supports scenarios where users seek to perform different parts…

As the Lakehouse architecture becomes more widespread, ensuring the reproducibility of data workloads over data lakes emerges as a crucial concern for data engineers. However, achieving reproducibility remains challenging. The size of data…

Data engineering pipelines are a widespread way to provide high-quality data for all kinds of data science applications. However, numerous challenges still remain in the composition and operation of such pipelines. Data engineering…

Increasingly larger number of software systems today are including data science components for descriptive, predictive, and prescriptive analytics. The collection of data science stages from acquisition, to cleaning/curation, to modeling,…

We describe how Python can be leveraged to streamline the curation, modelling and dissemination of drug discovery data as well as the development of innovative, freely available tools for the related scientific community. We look at various…

As artificial intelligence becomes increasingly prevalent in scientific research, data-driven methodologies appear to overshadow traditional approaches in resolving scientific problems. In this Perspective, we revisit a classic…

In the rapidly evolving domain of next generation sequencing and bioinformatics analysis, data generation is one aspect that is increasing at a concomitant rate. The burden associated with processing large amounts of sequencing data has…

This paper describes a machine learning and data science pipeline for structured information extraction from documents, implemented as a suite of open-source tools and extensions to existing tools. It centers around a methodology for…

In recent years, we have witnessed the growing interest from academia and industry in applying data science technologies to analyze large amounts of data. In this process, a myriad of artifacts (datasets, pipeline scripts, etc.) are…

This paper targets the execution of data science (DS) pipelines supported by data processing, transmission and sharing across several resources executing greedy processes. Current data science pipelines environments provide various…

Solutions to the Algorithm Selection Problem (ASP) in machine learning face the challenge of high computational costs associated with evaluating various algorithms' performances on a given dataset. To mitigate this cost, the meta-learning…

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…