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Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

计算机视觉与模式识别 · 计算机科学 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

With the rapid advancement of deep learning, computational pathology has made significant progress in cancer diagnosis and subtyping. Tissue segmentation is a core challenge, essential for prognosis and treatment decisions. Weakly…

计算机视觉与模式识别 · 计算机科学 2025-01-08 Hongyi Wu , Hong Zhang

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

计算机视觉与模式识别 · 计算机科学 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Deep neural networks have reached remarkable achievements in medical image processing tasks, specifically in classifying and detecting various diseases. However, when confronted with limited data, these networks face a critical…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Matina Mahdizadeh Sani , Ali Royat , Mahdieh Soleymani Baghshah

Lesion segmentation in medical imaging serves as an effective tool for assessing tumor sizes and monitoring changes in growth. However, not only is manual lesion segmentation time-consuming, but it is also expensive and requires expert…

计算机视觉与模式识别 · 计算机科学 2020-01-28 Vatsal Agarwal , Youbao Tang , Jing Xiao , Ronald M. Summers

This work addresses the task of completely weakly supervised class-incremental learning for semantic segmentation to learn segmentation for both base and additional novel classes using only image-level labels. While class-incremental…

计算机视觉与模式识别 · 计算机科学 2025-05-19 David Minkwan Kim , Soeun Lee , Byeongkeun Kang

We present an approach to learn a dense pixel-wise labeling from image-level tags. Each image-level tag imposes constraints on the output labeling of a Convolutional Neural Network (CNN) classifier. We propose Constrained CNN (CCNN), a…

计算机视觉与模式识别 · 计算机科学 2015-10-20 Deepak Pathak , Philipp Krähenbühl , Trevor Darrell

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

计算机视觉与模式识别 · 计算机科学 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Image segmentation is one of the most essential biomedical image processing problems for different imaging modalities, including microscopy and X-ray in the Internet-of-Medical-Things (IoMT) domain. However, annotating biomedical images is…

计算机视觉与模式识别 · 计算机科学 2021-01-25 Ziyuan Zhao , Zeng Zeng , Kaixin Xu , Cen Chen , Cuntai Guan

A large labeled dataset is a key to the success of supervised deep learning, but for medical image segmentation, it is highly challenging to obtain sufficient annotated images for model training. In many scenarios, unannotated images are…

计算机视觉与模式识别 · 计算机科学 2021-07-13 Hao Zheng , Jun Han , Hongxiao Wang , Lin Yang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

This paper presents a weakly supervised image segmentation method that adopts tight bounding box annotations. It proposes generalized multiple instance learning (MIL) and smooth maximum approximation to integrate the bounding box tightness…

计算机视觉与模式识别 · 计算机科学 2021-10-25 Juan Wang , Bin Xia

Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

计算机视觉与模式识别 · 计算机科学 2019-07-29 Zhenlin Xu , Marc Niethammer

Weakly supervised image segmentation approaches in the literature usually achieve high segmentation performance using tight bounding box supervision and decrease the performance greatly when supervised by loose bounding boxes. However,…

计算机视觉与模式识别 · 计算机科学 2023-01-31 Juan Wang , Bin Xia

Many computer vision systems require low-cost segmentation algorithms based on deep learning, either because of the enormous size of input images or limited computational budget. Common solutions uniformly downsample the input images to…

计算机视觉与模式识别 · 计算机科学 2022-08-19 Chen Jin , Ryutaro Tanno , Thomy Mertzanidou , Eleftheria Panagiotaki , Daniel C. Alexander

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment. These learning…

图像与视频处理 · 电气工程与系统科学 2022-11-22 Iain Carmichael , Andrew H. Song , Richard J. Chen , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang