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We employ a three-dimensional molecular dynamics to simulate translocation of a polymer through a nanopore driven by an external force. The translocation is investigated for different three pore diameter and two different external forces.…

计算物理 · 物理学 2019-12-03 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

We revisit the Fokker-Planck based theory of driven polymer translocation through a narrow nanopore. A bead-spring model of a uniformly charged polyelectrolyte chain translocating through a semi-implicit model of a nanopore embedded in a…

软凝聚态物质 · 物理学 2025-12-02 Bhavesh R. Sarode , Harshwardhan H. Katkar

The motion of polymers with inhomogeneous structure through nanopores is discussed theoretically. Specifically, we consider the translocation dynamics of polymers consisting of double-stranded and single-stranded blocks. Since only the…

统计力学 · 物理学 2009-11-11 Stanislav Kotsev , Anatoly B. Kolomeisky

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

统计力学 · 物理学 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We investigate the problem of polymer translocation through a nanopore in the absence of an external driving force. To this end, we use the two-dimensional (2D) fluctuating bond model with single-segment Monte Carlo moves. To overcome the…

计算物理 · 物理学 2012-12-06 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying

Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium.…

软凝聚态物质 · 物理学 2015-06-12 James M. Polson , Anthony C. M. McCaffrey

Polymer translocation through a nanopore in a membrane investigated theoretically. Recent experiments on voltage-driven DNA and RNA translocations through a nanopore indicate that the size and geometry of the pore are important factors in…

统计力学 · 物理学 2009-11-07 Elena Slonkina , Anatoly B. Kolomeisky

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

生物大分子 · 定量生物学 2009-11-13 Michel G. Gauthier , Gary W. Slater

Using Langevin dynamics simulations, we investigate the influence of polymer-pore interactions on the dynamics of biopolymer translocation through nanopores. We find that an attractive interaction can significantly change the translocation…

软凝聚态物质 · 物理学 2008-12-21 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

Brownian dynamics (BD) simulations are used to study the translocation dynamics of a coarse-grained polymer through a cylindrical nanopore. We consider the case of short polymers, with a polymer length, N, in the range N=21-61. The rate of…

软凝聚态物质 · 物理学 2015-06-18 James M. Polson , Taylor Dunn

The translocation dynamics of a polymer chain through a nanopore in the absence of an external driving force is analyzed by means of scaling arguments, fractional calculus, and computer simulations. The problem at hand is mapped on a one…

软凝聚态物质 · 物理学 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We consider the escape of a flexible, self-avoiding polymer chain out of a confined geometry. By means of simulations, we demonstrate that the translocation time can be described by a simple scaling law that exhibits a nonlinear dependence…

软凝聚态物质 · 物理学 2009-11-11 Angelo Cacciuto , Erik Luijten

Using continuous time Monte-Carlo method we simulated the translocation of a polynucleotide chain driven through a nanopore by an electric field. We have used two models of driven diffusion due to the electric field. The chain may have…

软凝聚态物质 · 物理学 2009-11-11 Pui-Man Lam , Fei Liu , Zhong-can OuYang

Here using LAMMPS molecular dynamics (MD) software, we simulate polymer translocation in 2 dimensions. We do the simulations for weak and moderate forces and for different pore diameters. Our results show that in both non-equilibrium and…

计算物理 · 物理学 2018-04-26 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

Using Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a circular nanocontainer through a nanopore under a driving force $F$. We observe that the translocation probability initially increases and then…

软凝聚态物质 · 物理学 2012-12-06 Kehong Zhang , Kaifu Luo

One of the major theoretical methods in understanding polymer translocation through a nanopore is the Fokker-Planck formalism based on the assumption of quasi-equilibrium of polymer conformations. The criterion for applicability of the…

软凝聚态物质 · 物理学 2018-02-14 Harshwardhan H. Katkar , Murugappan Muthukumar

We consider single particle and polymer translocation where the frictional properties experienced from the environment are changing in time. This work is motivated by the interesting frequency responsive behaviour observed when a polymer is…

软凝聚态物质 · 物理学 2012-12-06 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

Using two dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter $R$ through a nanopore under a driving force $F$. Due to the crowding effect induced by the…

软凝聚态物质 · 物理学 2010-08-30 Kaifu Luo , Ralf Metzler

We investigate the translocation of stiff polymers in the presence of binding particles through a nanopore by two-dimensional Langevin dynamics simulations. We find that the mean translocation time shows a minimum as a function of the…

软凝聚态物质 · 物理学 2015-06-12 Wancheng Yu , Yiding Ma , Kaifu Luo

We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength $E$,…

软凝聚态物质 · 物理学 2011-08-26 Kaifu Luo , Ilkka Huopaniemi , Tapio Ala-Nissila , See-Chen Ying
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