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Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative…

机器学习 · 计算机科学 2025-11-11 Ziyang Gao , Annie Cheung , Yihao Ou

Gastrointestinal malignancies constitute a leading cause of cancer-related mortality worldwide, with advanced-stage prognosis remaining particularly dismal. Originating as a groundbreaking technique for early gastric cancer treatment,…

计算机视觉与模式识别 · 计算机科学 2025-08-12 Xiangning Zhang , Jinnan Chen , Qingwei Zhang , Yaqi Wang , Chengfeng Zhou , Xiaobo Li , Dahong Qian

Early detection of precancerous cysts or neoplasms, i.e., Intraductal Papillary Mucosal Neoplasms (IPMN), in pancreas is a challenging and complex task, and it may lead to a more favourable outcome. Once detected, grading IPMNs accurately…

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Inspired by "predictive coding" - a theory in neuroscience, we develop a bi-directional and dynamic neural network with local recurrent processing, namely predictive coding network (PCN). Unlike feedforward-only convolutional neural…

计算机视觉与模式识别 · 计算机科学 2018-10-29 Kuan Han , Haiguang Wen , Yizhen Zhang , Di Fu , Eugenio Culurciello , Zhongming Liu

Pancreatic cancer has the poorest prognosis among all cancer types. Intraductal Papillary Mucinous Neoplasms (IPMNs) are radiographically identifiable precursors to pancreatic cancer; hence, early detection and precise risk assessment of…

计算机视觉与模式识别 · 计算机科学 2018-10-15 Sarfaraz Hussein , Pujan Kandel , Juan E. Corral , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

Early and accurate prediction of sepsis onset remains a major challenge in intensive care, where timely detection and subsequent intervention can significantly improve patient outcomes. While machine learning models have shown promise in…

机器学习 · 计算机科学 2025-09-26 Christoph Düsing , Philipp Cimiano

Survival prediction for esophageal squamous cell cancer (ESCC) is crucial for doctors to assess a patient's condition and tailor treatment plans. The application and development of multi-modal deep learning in this field have attracted…

图像与视频处理 · 电气工程与系统科学 2024-08-27 Chengyu Wu , Yatao Zhang , Yaqi Wang , Qifeng Wang , Shuai Wang

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Pre-trained language models have led to substantial gains over a broad range of natural language processing (NLP) tasks, but have been shown to have limitations for natural language generation tasks with high-quality requirements on the…

计算与语言 · 计算机科学 2021-09-15 Haonan Li , Yeyun Gong , Jian Jiao , Ruofei Zhang , Timothy Baldwin , Nan Duan

We demonstrate a machine learning based approach which can learn the time-dependent electronic excitation dynamics of small molecules subjected to ion irradiation. Ensembles of recurrent neural networks are trained on data generated by…

化学物理 · 物理学 2024-09-24 Ethan P. Shapera , Cheng-Wei Lee

Graph neural networks (GNNs) are becoming increasingly popular in the medical domain for the tasks of disease classification and outcome prediction. Since patient data is not readily available as a graph, most existing methods either…

计算机视觉与模式识别 · 计算机科学 2023-10-05 Nithya Bhasker , Stefan Leger , Alexander Zwanenburg , Chethan Babu Reddy , Sebastian Bodenstedt , Steffen Löck , Stefanie Speidel

Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class…

定量方法 · 定量生物学 2022-08-17 Mirko Hu , Guido Caldarelli , Tommaso Gili

Predictive coding networks (PCNs) are an influential model for information processing in the brain. They have appealing theoretical interpretations and offer a single mechanism that accounts for diverse perceptual phenomena of the brain. On…

机器学习 · 计算机科学 2021-03-08 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

Inductive Conformal Prediction (ICP) is a set of distribution-free and model agnostic algorithms devised to predict with a user-defined confidence with coverage guarantee. Instead of having point predictions, i.e., a real number in the case…

机器学习 · 统计学 2022-07-05 Martim Sousa

Deep learning has shown its human-level performance in various applications. However, current deep learning models are characterised by catastrophic forgetting of old knowledge when learning new classes. This poses a challenge particularly…

机器学习 · 计算机科学 2022-04-29 Yang Yang , Zhiying Cui , Junjie Xu , Changhong Zhong , Wei-Shi Zheng , Ruixuan Wang

Feedforward CNN models have proven themselves in recent years as state-of-the-art models for predicting single-neuron responses to natural images in early visual cortical neurons. In this paper, we extend these models with recurrent…

神经与进化计算 · 计算机科学 2022-11-15 Yimeng Zhang , Harold Rockwell , Sicheng Dai , Ge Huang , Stephen Tsou , Yuanyuan Wei , Tai Sing Lee

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

神经与进化计算 · 计算机科学 2010-09-28 S. M. Kamruzzaman , Ahmed Ryadh Hasan , Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder

Gastrointestinal diseases impose a growing global health burden, and endoscopy is a primary tool for early diagnosis. However, routine endoscopic image interpretation still suffers from missed lesions and limited efficiency. Although…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Peixi Peng , Housheng Xie , Yanling Wei , Guangcong Ruan , Xiaoyang Zou , Qian Cao , Yongjian Nian , Guoyan Zheng