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In this paper, we present an effective deep prediction framework based on robust recurrent neural networks (RNNs) to predict the likely therapeutic classes of medications a patient is taking, given a sequence of diagnostic billing codes in…

机器学习 · 计算机科学 2020-01-29 Deyin Liu , Lin Wu , Xue Li

Causal inference and model interpretability research are gaining increasing attention, especially in the domains of healthcare and bioinformatics. Despite recent successes in this field, decorrelating features under nonlinear environments…

机器学习 · 计算机科学 2022-09-30 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline Thirukumaran , Addisu Mesfin , Jiebo Luo

The increasing capture and analysis of large-scale longitudinal health data offer opportunities to improve healthcare and advance medical understanding. However, a critical gap exists between (a) -- the observation of patterns and…

人机交互 · 计算机科学 2025-08-26 Arran Zeyu Wang , David Borland , David Gotz

Comparing different neural network representations and determining how representations evolve over time remain challenging open questions in our understanding of the function of neural networks. Comparing representations in neural networks…

机器学习 · 统计学 2018-10-25 Ari S. Morcos , Maithra Raghu , Samy Bengio

Direct Coupling Analysis (DCA) is a now widely used method to leverage statistical information from many similar biological systems to draw meaningful conclusions on each system separately. DCA has been applied with great success to…

种群与进化 · 定量生物学 2018-08-13 Chen-Yi Gao , Fabio Cecconi , Angelo Vulpiani , Hai-Jun Zhou , Erik Aurell

Causal decomposition analysis (CDA) is an approach for modeling the impact of hypothetical interventions to reduce disparities. It is useful for identifying foci that future interventions, including multilevel and multimodal interventions,…

统计方法学 · 统计学 2026-04-28 John W. Jackson , Ting-Hsuan Chang , Aster Meche , Trang Q. Nguyen

Modern biomedical studies often collect multi-view data, that is, multiple types of data measured on the same set of objects. A popular model in high-dimensional multi-view data analysis is to decompose each view's data matrix into a…

机器学习 · 统计学 2022-09-19 Hai Shu , Zhe Qu , Hongtu Zhu

In this paper, we propose a deep probabilistic multi-view model that is composed of a linear multi-view layer based on probabilistic canonical correlation analysis (CCA) description in the latent space together with deep generative networks…

机器学习 · 计算机科学 2020-03-10 Mahdi Karami , Dale Schuurmans

We present a novel method for solving Canonical Correlation Analysis (CCA) in a sparse convex framework using a least squares approach. The presented method focuses on the scenario when one is interested in (or limited to) a primal…

机器学习 · 统计学 2009-08-20 David R. Hardoon , John Shawe-Taylor

Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

图像与视频处理 · 电气工程与系统科学 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

Sensor technologies are becoming increasingly prevalent in the biomedical field, with applications ranging from telemonitoring of people at risk, to using sensor derived information as objective endpoints in clinical trials. To fully…

机器学习 · 计算机科学 2021-07-27 Narayan Schütz , Angela Botros , Michael Single , Aileen C. Naef , Philipp Buluschek , Tobias Nef

Medical image segmentation is one of the fundamental problems for artificial intelligence-based clinical decision systems. Current automatic medical image segmentation methods are often failed to meet clinical requirements. As such, a…

计算机视觉与模式识别 · 计算机科学 2021-11-16 Wenhao Li , Qisen Xu , Chuyun Shen , Bin Hu , Fengping Zhu , Yuxin Li , Bo Jin , Xiangfeng Wang

In healthcare prediction tasks, it is essential to exploit the correlations between medical features and learn better patient health representations. Existing methods try to estimate feature correlations only from data, or increase the…

机器学习 · 计算机科学 2022-05-24 Xinyu Ma , Xu Chu , Yasha Wang , Hailong Yu , Liantao Ma , Wen Tang , Junfeng Zhao

Various new brain-computer interface technologies or neuroscience applications require decoding stimulus-following neural responses to natural stimuli such as speech and video from, e.g., electroencephalography (EEG) signals. In this…

信号处理 · 电气工程与系统科学 2024-08-01 Simon Geirnaert , Yuanyuan Yao , Tom Francart , Alexander Bertrand

We present an efficient stochastic algorithm (RSG+) for canonical correlation analysis (CCA) using a reparametrization of the projection matrices. We show how this reparametrization (into structured matrices), simple in hindsight, directly…

机器学习 · 计算机科学 2021-06-15 Zihang Meng , Rudrasis Chakraborty , Vikas Singh

Classical methods such as Principal Component Analysis (PCA) and Canonical Correlation Analysis (CCA) are ubiquitous in statistics. However, these techniques are only able to reveal linear relationships in data. Although nonlinear variants…

机器学习 · 统计学 2014-05-14 David Lopez-Paz , Suvrit Sra , Alex Smola , Zoubin Ghahramani , Bernhard Schölkopf

We suggest an enhancement to structural coding through the use of (a) causally bound codes, (b) basic constructs of graph theory and (c) statistics. As is the norm with structural coding, the codes are collected into categories. The…

数字图书馆 · 计算机科学 2021-07-30 Etienne-Victor Depasquale , Humaira Abdul Salam , Franco Davoli

Canonical correlation analysis is a widely used multivariate statistical technique for exploring the relation between two sets of variables. This paper considers the problem of estimating the leading canonical correlation directions in…

统计理论 · 数学 2015-10-16 Chao Gao , Zongming Ma , Zhao Ren , Harrison H. Zhou

As electronically stored data grow in daily life, obtaining novel and relevant information becomes challenging in text mining. Thus people have sought statistical methods based on term frequency, matrix algebra, or topic modeling for text…

信息检索 · 计算机科学 2019-07-04 Clint P. George , Wei Xia , George Michailidis

The Canonical Correlation Analysis (CCA) family of methods is foundational in multiview learning. Regularised linear CCA methods can be seen to generalise Partial Least Squares (PLS) and be unified with a Generalized Eigenvalue Problem…

机器学习 · 计算机科学 2024-05-02 James Chapman , Lennie Wells , Ana Lawry Aguila