相关论文: One-dimensional Arterial Network Model for Bypass …
Stochastically evolving geometric systems are studied in shape analysis and computational anatomy for modelling random evolutions of human organ shapes. The notion of geodesic paths between shapes is central to shape analysis and has a…
Haemodynamic indices derived from Computational Fluid Dynamics (CFD), such as Time-averaged Wall Shear Stress (TAWSS) and Oscillatory Shear Index (OSI), are closely associated with restenosis risk in Peripheral Arterial Disease (PAD).…
Modeling gas flow through fractures of subsurface rock is a particularly challenging problem because of the heterogeneous nature of the material. High-fidelity simulations using discrete fracture network (DFN) models are one methodology for…
A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…
Large neck vessels (carotid artery and internal jugular vein, IJV) offer a unique opportunity to monitor hemodynamics non-invasively by optical means. The primary shortcoming of past work has been the focus on healthy volunteers in normal…
Arterial tissue consists of multiple structurally important constituents that have individual material properties and associated stress-free configurations that evolve over time. This gives rise to residual stresses contributing to the…
Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…
Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…
The calibration of a PointQ arterial microsimulation model is formulated as a quadratic programming problem (QP) whose decision variables are link flows, demands at entry links, and turn movements at intersections, subject to linear…
Blood vessel networks form by spontaneous aggregation of individual cells migrating toward vascularization sites (vasculogenesis). A successful theoretical model of two dimensional experimental vasculogenesis has been recently proposed,…
Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…
The global burden of acute and chronic wounds presents a compelling case for enhancing wound classification methods, a vital step in diagnosing and determining optimal treatments. Recognizing this need, we introduce an innovative…
Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…
Cardiac segmentation of atriums, ventricles, and myocardium in computed tomography (CT) images is an important first-line task for presymptomatic cardiovascular disease diagnosis. In several recent studies, deep learning models have shown…
We derive a one-dimensional (1d) model for the analysis of bulging or necking in an inflated hyperelastic tube of {\it finite wall thickness} from the three-dimensional finite elasticity theory by applying the dimension reduction…
Collateral circulation results from specialized anastomotic channels which are capable of providing oxygenated blood to regions with compromised blood flow caused by ischemic injuries. The quality of collateral circulation has been…
We derive a unidirectional asymptotic model for one-dimensional blood flow in viscoelastic arteries. We prove local well-posedness of strong solutions in Sobolev spaces for general parameters and mean-zero periodic data. In the purely…
Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools for studying cardiovascular systems. However, solving the corresponding inverse problem of…
Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…
A new mathematical model and numerical approach are proposed for the simulation of fluid and chemical exchanges between a growing capillary network and the surrounding tissue, in the context of tumor-induced angiogenesis. Thanks to proper…