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Consumption of antimicrobial drugs, such as antibiotics, is linked with antimicrobial resistance. Surveillance of antimicrobial drug consumption is therefore an important element in dealing with antimicrobial resistance. Many countries lack…

信息检索 · 计算机科学 2018-03-12 Niels Dalum Hansen , Kåre Mølbak , Ingemar Cox , Christina Lioma

Consumer protection agencies are charged with safeguarding the public from hazardous products, but the thousands of products under their jurisdiction make it challenging to identify and respond to consumer complaints quickly. From the…

信息检索 · 计算机科学 2017-03-03 Shreesh Kumara Bhat , Aron Culotta

Repurposing existing drugs to treat new diseases is a cost-effective alternative to de novo drug development, but there are millions of potential drug-disease combinations to be considered with only a small fraction being viable. In silico…

定量方法 · 定量生物学 2025-10-24 Austin Polanco , M. E. J. Newman

Drug shortages occur frequently and are often caused by supply chain disruptions. For improvements to occur, it is necessary to be able to estimate the vulnerability of pharmaceutical supply chains. In this work, we present the first model…

最优化与控制 · 数学 2022-04-26 Emily L. Tucker , Mark S. Daskin

Studies have shown that the traces people leave when browsing the internet may indicate the onset of diseases such as cancer. Here we show that the adaptive engines of advertising systems in conjunction with clinically verified…

计算机与社会 · 计算机科学 2018-08-09 Elad Yom-Tov

The internet has changed the way we live, work and take decisions. As it is the major modern resource for research, detailed data on internet usage exhibits vast amounts of behavioral information. This paper aims to answer the question…

计量经济学 · 经济学 2022-06-02 Christopher Bockel-Rickermann

Search-engine date filters are widely used to enforce pre-cutoff retrieval in retrospective evaluations of search-augmented forecasters. We show this approach is unreliable across two major search engines: auditing Google Search's before:…

计算与语言 · 计算机科学 2026-04-22 Ali El Lahib , Ying-Jieh Xia , Zehan Li , Yuxuan Wang , Xinyu Pi

We live in a computerized and networked society where many of our actions leave a digital trace and affect other people's actions. This has lead to the emergence of a new data-driven research field: mathematical methods of computer science,…

Online medical forums are a rich and underutilized source of insight into patient concerns, especially regarding medication use. Some of the many questions users pose may signal confusion, misuse, or even the early warning signs of a…

计算与语言 · 计算机科学 2025-09-16 Dvora Goncharok , Arbel Shifman , Alexander Apartsin , Yehudit Aperstein

COVID19 was first reported in England at the end of January 2020, and by mid-June over 150,000 cases were reported. We assume that, similarly to influenza-like illnesses, people who suffer from COVID19 may query for their symptoms prior to…

信息检索 · 计算机科学 2020-07-24 Elad Yom-Tov , Vasileios Lampos , Ingemar J. Cox , Michael Edelstein

Illicit online pharmacies allow the purchase of prescription drugs online without a prescription. Such pharmacies leverage social media platforms such as Twit- ter as a promotion and marketing tool with the intent of reaching out to a…

计算机与社会 · 计算机科学 2017-12-05 Janani Kalyanam , Timothy Mackey

Patients are increasingly using large language models (LLMs) to seek answers to their healthcare-related questions. However, benchmarking efforts in LLMs for question answering often focus on medical exam questions, which differ…

计算与语言 · 计算机科学 2026-03-19 Raymond Xiong , Furong Jia , Lionel Wong , Monica Agrawal

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

定量方法 · 定量生物学 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

Mining social media messages for health and drug related information has received significant interest in pharmacovigilance research. Social media sites (e.g., Twitter), have been used for monitoring drug abuse, adverse reactions of drug…

计算与语言 · 计算机科学 2018-05-17 Debanjan Mahata , Jasper Friedrichs , Hitkul , Rajiv Ratn Shah

In this paper, we present an effective deep prediction framework based on robust recurrent neural networks (RNNs) to predict the likely therapeutic classes of medications a patient is taking, given a sequence of diagnostic billing codes in…

机器学习 · 计算机科学 2020-01-29 Deyin Liu , Lin Wu , Xue Li

Search components in e-commerce apps, often complex AI-based systems, are prone to bugs that can lead to missed recalls - situations where items that should be listed in search results aren't. This can frustrate shop owners and harm the…

软件工程 · 计算机科学 2024-07-01 Shengnan Wu , Yongxiang Hu , Yingchuan Wang , Jiazhen Gu , Jin Meng , Liujie Fan , Zhongshi Luan , Xin Wang , Yangfan Zhou

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to…

定量方法 · 定量生物学 2025-05-21 Fatma Zahra Abdeldjouad , Menaouer Brahami , Mohammed Sabri

The United States Food and Drug Administration's (FDA's) 510(k) pathway allows manufacturers to gain medical device approval by demonstrating substantial equivalence to a legally marketed device. However, the inherent ambiguity of this…

机器学习 · 计算机科学 2026-01-30 Mohammad Zhalechian , Soroush Saghafian , Omar Robles

Substance use is a global issue that negatively impacts millions of persons who use drugs (PWUDs). In practice, identifying vulnerable PWUDs for efficient allocation of appropriate resources is challenging due to their complex use patterns…

In pre-market drug safety review, grouping related adverse event terms into standardised MedDRA queries or the FDA Office of New Drugs Custom Medical Queries (OCMQs) is critical for signal detection. We present a novel quantitative…

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