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Quantification of sulfated polysaccharides in urine samples is relevant to pharmacokinetic studies in drug development projects and to the non-invasive diagnosis and therapy monitoring of mucopolysaccharidoses. The Heparin Red Kit is a…

定量方法 · 定量生物学 2018-11-26 Ulrich Warttinger , Roland Krämer

Sulfated polysaccharides constitute a large and complex group of macromolecules which possess a wide range of important biological properties. Many of them hold promise as new therapeutics, but determination of their blood levels during…

定量方法 · 定量生物学 2017-12-19 Ulrich Warttinger , Christina Giese , Roland Krämer

Heparins are are sulfated polysaccharides that have tremendous clinical importance as anticoagulant drugs. Monitoring of heparin blood levels can improve patient safety. In clinical practice, heparins are monitored indirectly by their…

定量方法 · 定量生物学 2017-12-12 Ulrich Warttinger , Christina Giese , Roland Krämer

Dextran sulfate is semi-synthetic, polydisperse sulfated polysaccharide with important applications in clinical practice, in the manufacturing of plasma derived protein therapeutics and in biomedical research. The sensitive detection of…

定量方法 · 定量生物学 2017-03-28 Nathalie Groß , Dumitru Arian , Ulrich Warttinger , Roland Krämer

Heparan sulfate (HS) is a linear, polydisperse sulfated polysaccharide belonging to the glycosaminoglycan family. HS proteoglycans are ubiquitously found at the cell surface and extracellular matrix in animal species. HS is involved in the…

定量方法 · 定量生物学 2017-02-20 Ulrich Warttinger , Roland Krämer

Fucoidan is a generic term for a class of fucose rich, structurally diverse sulfated polysaccharides that are found in brown algae and other marine organisms. Depending on the species from which the fucoidan is extracted, a wide variety of…

定量方法 · 定量生物学 2016-08-02 Ulrich Warttinger , Christina Giese , Job Harenberg , Roland Krämer

Refractive index is a fundamental optical property of powder and a key input to the measurement of the size distribution using light scattering and the measurement of the absorption and scattering coefficients using diffuse reflectance…

光学 · 物理学 2024-03-05 Cory Juntunen , Adam J. Rish , Carl Anderson , Yongjin Sung

Africa is the world region that is most affected by malaria. Among the therapies used, injectable quinine is considered to be one of the effective antimalarial drug, however non-quality assured antimalarials clearly have a strong market…

光学 · 物理学 2025-10-06 A. Sow , I. Traore , T. Diallo , A. BA

Urea and creatinine are two important diagnostic components of urine. The study of creatinine in liquid phase is difficult due to its feeble concentration in urine. To bring down the detection limit, Raman spectroscopy of dried urine…

医学物理 · 物理学 2014-12-24 S. Kumar , S. K. Majumdar

This paper presents a smartphone-based imaging system capable of quantifying the concentration of an assortment of biological/chemical assay samples. The main objective is to construct an image database which characterizes the relationship…

图像与视频处理 · 电气工程与系统科学 2026-04-17 Zhendong Cao , Hongji Dai , Zhida Li , Ash Parameswaran

The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…

光学 · 物理学 2025-09-18 Zhonghao Li , Zhihan Cai , Chaoyang Gong

Thick tissue sections strongly scatter and absorb light, which limits transmission-based label-free examination via quantitative phase imaging (QPI) modalities. Here we introduce a simple, room-temperature optical clearing medium - glycerol…

Urine sediment examination (USE) is one of the main tests used in the evaluation of diseases such as kidney, urinary, metabolic, and diabetes and to determine the density and number of various cells in the urine. USE's manual microscopy is…

定量方法 · 定量生物学 2023-02-23 Taner Tuncer , Merve Erkuş , Ahmet Çınar , Hakan Ayyıldız , Seda Arslan Tuncer

A key challenge in sequential decision making is optimizing systems safely under partial information. While much of the literature has focused on the cases of either partially known states or partially known dynamics, it is further…

最优化与控制 · 数学 2023-04-21 Qinyang He , Yonatan Mintz

Minerals detection over large volume of spectra is the challenge addressed by current hyperspectral imaging spectrometer in Planetary Science. Instruments such OMEGA (Mars Express), CRISM (Mars Reconnaissance Orbiter), M^{3}…

地球与行星天体物理 · 物理学 2014-04-14 Schmidt Frederic , Legendre Maxime , Le Mouelic Stephane

Common transparent polymer films such as cellophane and household tape are frequently used as examples of birefringent materials in textbooks and classroom demonstrations. Qualitatively, birefringence is often demonstrated by layering such…

物理教育 · 物理学 2022-08-10 Aaron D. Slepkov

A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin…

医学物理 · 物理学 2017-12-04 Chris Wu , Tanay Tandon

Falsification of medicines is a big problem in many developing countries, where technological infrastructure is inadequate to detect these harmful products. We have developed a set of inexpensive paper cards, called Paper Analytical Devices…

计算机视觉与模式识别 · 计算机科学 2017-04-17 Sandipan Banerjee , James Sweet , Christopher Sweet , Marya Lieberman

Due to the significant resemblance in visual appearance, pill misuse is prevalent and has become a critical issue, responsible for one-third of all deaths worldwide. Pill identification, thus, is a crucial concern needed to be investigated…

计算机视觉与模式识别 · 计算机科学 2023-03-20 Anh Duy Nguyen , Huy Hieu Pham , Huynh Thanh Trung , Quoc Viet Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

Rapid and non-destructive assessment of milk quality is crucial to ensuring both nutritional value and food safety. In this study, we investigated the potential of visible and hyperspectral imaging as cost-effective and quick-response…

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