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The preB\"otzinger Complex, the mammalian inspiratory rhythm generator, encodes inspiratory time as motor pattern. Spike synchronization throughout this sparsely connected network generates inspiratory bursts albeit with variable latencies…

神经元与认知 · 定量生物学 2020-12-24 Valentin M. Slepukhin , Sufyan Ashhad , Jack L. Feldman , Alex J. Levine

Inhibition is considered to shape neural activity, and broaden its pattern repertoire. In the sensory organs, where the anatomy of neural circuits is highly structured, lateral inhibition sharpens contrast among stimulus properties. The…

神经元与认知 · 定量生物学 2018-09-18 Netta Haroush , Shimon Marom

In the classic view of cortical rhythms, the interaction between excitatory pyramidal neurons (E) and inhibitory parvalbumin neurons (I) has been shown to be sufficient to generate gamma and beta band rhythms. However, it is now clear that…

神经元与认知 · 定量生物学 2025-10-27 Arnab Dey Sarkar , Bard Ermentrout

Gamma-band rhythmic inhibition is a ubiquitous phenomenon in neural circuits yet its computational role still remains elusive. We show that a model of Gamma-band rhythmic inhibition allows networks of coupled cortical circuit motifs to…

神经元与认知 · 定量生物学 2017-11-08 Hesham Mostafa , Lorenz K. Muller , Giacomo Indiveri

Respiration is an essential involuntary function necessary for survival. This poses a challenge for the control of breathing. The preB\"otzinger complex (preB\"otC) is a heterogeneous neuronal network responsible for driving the inspiratory…

神经元与认知 · 定量生物学 2026-04-09 Sreshta Venkatakrishnan , Andrew K. Tryba , Alfredo J. Garcia , Yangyang Wang

Neuronal heterogeneity, characterized by the presence of a multitude of spiking neuronal patterns, is a widespread phenomenon throughout the nervous system. In particular, the brain exhibits strong variability among inhibitory neurons.…

神经元与认知 · 定量生物学 2024-12-02 Katiele V. P. Brito , Joana M. G. L. Silva , Claudio R. Mirasso , Fernanda S. Matias

Rich, spontaneous brain activity has been observed across a range of different temporal and spatial scales. These dynamics are thought to be important t for efficient neural functioning. Experimental evidence suggests that these neural…

神经元与认知 · 定量生物学 2015-01-21 Peter J. Hellyer , Barbara Jachs , Robert Leech , Claudia Clopath

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

神经元与认知 · 定量生物学 2021-04-08 R. Janaki , A. S. Vytheeswaran

We investigate the synchronization properties between two excitatory coupled neurons in the presence of an inhibitory loop mediated by an interneuron. Dynamical inhibition together with noise independently applied to each neuron provide…

神经元与认知 · 定量生物学 2016-11-23 Fernanda S. Matias , Leonardo L. Gollo , Pedro V. Carelli , Claudio R. Mirasso , Mauro Copelli

Networks of fast-spiking interneurons are crucial for the generation of neural oscillations in the brain. Here we study the synchronous behavior of interneuronal networks that are coupled by delayed inhibitory and fast electrical synapses.…

神经元与认知 · 定量生物学 2012-06-22 Daqing Guo , Qingyun Wang , Matjaz Perc

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

神经元与认知 · 定量生物学 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

神经元与认知 · 定量生物学 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

We study some mechanisms responsible for synchronous oscillations and loss of synchrony at physiologically relevant frequencies (10-200 Hz) in a network of heterogeneous inhibitory neurons. We focus on the factors that determine the level…

神经元与认知 · 定量生物学 2007-05-23 J. A. White , C. C. Chow , J. Ritt , C. Soto-Trevino , N. Kopell

The collective dynamics of a network of excitable nodes changes dramatically when inhibitory nodes are introduced. We consider inhibitory nodes which may be activated just like excitatory nodes but, upon activating, decrease the probability…

神经元与认知 · 定量生物学 2014-04-03 Daniel B. Larremore , Woodrow L. Shew , Edward Ott , Francesco Sorrentino , Juan G. Restrepo

We study a network of spiking neurons with heterogeneous excitabilities connected via inhibitory delayed pulses. For globally coupled systems the increase of the inhibitory coupling reduces the number of firing neurons by following a Winner…

无序系统与神经网络 · 物理学 2019-05-29 Stefano Luccioli , David Angulo Garcia , Alessandro Torcini

Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the neocortex of higher mammals is not well established. We investigated the dynamics…

The spatiotemporal patterns of neural dynamics are jointly shaped by directed structural interactions and heterogeneous intrinsic features of the neural components. Despite well-developed methods for estimating directionality in network…

神经元与认知 · 定量生物学 2025-10-07 Jiawen Chang , Zhuda Yang , Changsong Zhou

Complexity in the temporal organization of neural systems may be a reflection of the diversity of its neural constituents. These constituents, excitatory and inhibitory neurons, comprise an invariant ratio in vivo and form the substrate for…

神经元与认知 · 定量生物学 2015-05-18 Xin Chen , Rhonda Dzakpasu

We consider two neuronal networks coupled by long-range excitatory interactions. Oscillations in the gamma frequency band are generated within each network by local inhibition. When long-range excitation is weak, these oscillations…

神经元与认知 · 定量生物学 2009-11-13 Demian Battaglia , Nicolas Brunel , David Hansel

Oscillations are a hallmark of neural population activity in various brain regions with a spectrum covering a wide range of frequencies. Within this spectrum gamma oscillations have received particular attention due to their ubiquitous…

神经元与认知 · 定量生物学 2020-01-22 Hongjie Bi , Marco Segneri , Matteo di Volo , Alessandro Torcini
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