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While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

医学物理 · 物理学 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

医学物理 · 物理学 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Contrast-enhanced computed tomography angiograms (CTAs) are widely used in cardiovascular imaging to obtain a non-invasive view of arterial structures. However, contrast agents are associated with complications at the injection site as well…

图像与视频处理 · 电气工程与系统科学 2020-03-04 Anirudh Chandrashekar , Ashok Handa , Natesh Shivakumar , Pierfrancesco Lapolla , Vicente Grau , Regent Lee

The photon counting imaging paradigm in the visible and the infrared comes from the very small energy carried by a single photon at these wavelengths. Usually to detect photons the photoelectric effect is used. It converts a photon to a…

天体物理仪器与方法 · 物理学 2022-07-28 Jean-Luc Gach , Isaure De Kernier , Philippe Feautrier

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Principal Component Analysis (PCA) is a dimensionality reduction technique widely used to reduce the computational cost associated with numerical simulations of combustion phenomena. However, PCA, which transforms the thermo-chemical state…

流体动力学 · 物理学 2026-02-26 Anirudh Jonnalagadda , Shubham P. Kulkarni , Akash Rodhiya , Hemanth Kolla , Konduri Aditya

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT)…

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Twin entangled beams produced by single-pass parametric down-conversion (PDC) offer the opportunity to detect weak amount of absorption with an improved sensitivity with respect to standard techniques which make use of classical light…

量子物理 · 物理学 2009-11-13 E. Brambilla , L. Caspani , O. Jedrkiewicz , L. A. Lugiato , A. Gatti

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

Dual-energy CT (DECT) has been widely investigated to generate more informative and more accurate images in the past decades. For example, Dual-Energy Alternating Minimization (DEAM) algorithm achieves sub-percentage uncertainty in…

图像与视频处理 · 电气工程与系统科学 2021-08-03 Tao Ge , Maria Medrano , Rui Liao , David G. Politte , Jeffrey F. Williamson , Joseph A. O'Sullivan

Due to its remarkable energy compaction properties, the discrete cosine transform (DCT) is employed in a multitude of compression standards, such as JPEG and H.265/HEVC. Several low-complexity integer approximations for the DCT have been…

多媒体 · 计算机科学 2016-12-05 R. J. Cintra , F. M. Bayer , V. A. Coutinho , S. Kulasekera , A. Madanayake

Cone-beam breast computed tomography (CT) provides true 3D breast images with isotropic resolution and high-contrast information, detecting calcifications as small as a few hundred microns and revealing subtle tissue differences. However,…

医学物理 · 物理学 2019-12-18 Wenxiang Cong , Hongming Shan , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Dye attenuation, or photometric imaging, is an optical technique commonly used in fluid dynamics to measure tracer concentration fields and fluid thicknesses under the assumption that the motion of the dye is representative of the fluid…

流体动力学 · 物理学 2024-11-04 George T. Fortune , Merlin A. Etzold , Julien R. Landel , Stuart B. Dalziel

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

医学物理 · 物理学 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

Low-dose CT (LDCT) imaging is widely used to reduce radiation exposure to mitigate high exposure side effects, but often suffers from noise and artifacts that affect diagnostic accuracy. To tackle this issue, deep learning models have been…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Taifour Yousra , Beghdadi Azeddine , Marie Luong , Zuheng Ming

Purpose: The goal of this study was to assess the potential added benefit of accounting for partial volume effects (PVE) in an automatic coronary lumen segmentation algorithm from coronary computed tomography angiography (CCTA). Materials…

图像与视频处理 · 电气工程与系统科学 2019-06-25 Moti Freiman , Hannes Nickisch , Sven Prevrhal , Holger Schmitt , Mani Vembar , Pál Maurovich-Horvat , Patrick Donnelly , Liran Goshen

Compared with the start-of-art energy integration detectors (EIDs), photon-counting detectors (PCDs) with energy discrimination capabilities have demonstrated great potentials in various applications of medical x-ray radiography and…

医学物理 · 物理学 2018-05-01 Ruibin Feng , David Rundle , Ge Wang

Short-scan FDK reconstruction is widely used in preclinical cone-beam micro-CT because it reduces scan time and radiation dose, and because the large volume sizes typical of micro-CT make iterative methods impractical for routine use. Short…

医学物理 · 物理学 2026-04-28 Falk L Wiegmann , Nancy L Ford