相关论文: Global Sensitivity Analysis in a Mathematical Mode…
One-dimensional blood flow model accuracy has been verified in many studies. This work is about introducing gravity into a one-dimensional model. For this purpose, gravitational force was introduced into the existing model. The boundary…
The renal vasculature, acting as a resource distribution network, plays an important role in both the physiology and pathophysiology of the kidney. However, no imaging techniques allow an assessment of the structure and function of the…
Numerous are the questionings raised by medicine interventionnelle, concerning the hold in charge of the pathologies of the arterial partition (aneurysm, dissection, coarctation, atherosclerosis).for it we made the modeling and the numeric…
Objectives: To mathematically investigate urethral pressure and influencing parameters of stress urinary incontinence (SUI) in women, with focus on the clinical aspects of the mathematical modeling. Method: Several patients' data are…
This research examines the simultaneous influences of height and weight on longitudinally measured systolic and diastolic blood pressure in children. Previous studies have shown that both height and weight are positively associated with…
Background: Renal blood flow (RBF) is an important marker of kidney health, but noninvasive assessment is not routinely used in clinical imaging. We evaluated the feasibility and physiologic validity of quantifying renal transport of…
In this study we present a mathematical model describing the transport of sodium in a fluid circulating in a counter-current tubular architecture, which constitutes a simplified model of Henle's loop in a kidney nephron. The model…
Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow…
This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…
The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but arterial compliance is often modeled as a constant value, due to ease of…
Paediatric kidney disease varies widely in its presentation and progression, which calls for continuous monitoring of renal function. Using electronic health records collected between 2019 and 2025 at Great Ormond Street Hospital, a leading…
The influence of hypertension on low-density lipoproteins intake into the arterial wall is an important factor for understanding mechanisms of atherosclerosis. It has been experimentally observed that the increased pressure leads to the…
The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…
The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters. We employed a stimulation catheter inserted in the right renal artery…
The association between visit-to-visit systolic blood pressure variability and cardiovascular events has recently received a lot of attention in the cardiovascular literature. But blood pressure variability is usually estimated on a…
Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies including intracranial aneurysms and atherosclerosis. Recent computational work…
The invasive measurement of the hepatic venous pressure gradient is still considered as the reference method to assess the severity of portal hypertension. Even though previous studies have shown that the liver stiffness measured by…
Global sensitivity metrics are essential tools for assessing parameter importance in complex models, particularly when precise information about parameter values is unavailable. In many cases, such metrics are used to provide parameter…
In vitro models play a crucial role in advancing our understanding of biological processes, disease mechanisms, and developing screening platforms for drug discovery. Kidneys play an instrumental role in transport and elimination of drugs…