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Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

计算工程、金融与科学 · 计算机科学 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Diffusion MRI (dMRI) tractography enables in vivo mapping of brain structural connections, but traditional connectome generation is time-consuming and requires gray matter parcellation, posing challenges for large-scale studies. We…

图像与视频处理 · 电气工程与系统科学 2025-06-12 Marcus J. Vroemen , Yuqian Chen , Yui Lo , Tengfei Xue , Weidong Cai , Fan Zhang , Josien P. W. Pluim , Lauren J. O'Donnell

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

统计方法学 · 统计学 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

机器学习 · 计算机科学 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

Brain parcellations play a ubiquitous role in the analysis of magnetic resonance imaging (MRI) datasets. Over 100 years of research has been conducted in pursuit of an ideal brain parcellation. Different methods have been developed and…

神经元与认知 · 定量生物学 2021-07-09 Pantea Moghimi , Anh The Dang , Theoden I. Netoff , Kelvin O. Lim , Gowtham Atluri

Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

Currently, connectomes (e.g., functional or structural brain graphs) can be estimated in humans at $\approx 1~mm^3$ scale using a combination of diffusion weighted magnetic resonance imaging, functional magnetic resonance imaging and…

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

计算机视觉与模式识别 · 计算机科学 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Mapping from functional connectivity (FC) to structural connectivity (SC) can facilitate multimodal brain network fusion and discover potential biomarkers for clinical implications. However, it is challenging to directly bridge the reliable…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Qiankun Zuo , Bangjun Lei , Wanyu Qiu , Changhong Jing , Jin Hong , Shuqiang Wang

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

生物物理 · 物理学 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

神经元与认知 · 定量生物学 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

In structural brain networks the connections of interest consist of white-matter fibre bundles between spatially segregated brain regions. The presence, location and orientation of these white matter tracts can be derived using diffusion…

神经元与认知 · 定量生物学 2012-02-09 M. Hinne , T. Heskes , M. A. J. van Gerven

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

Human skill learning requires fine-scale coordination of distributed networks of brain regions that are directly linked to one another by white matter tracts to allow for effective information transmission. Yet how individual differences in…

神经元与认知 · 定量生物学 2016-10-25 Ari E. Kahn , Marcelo G. Mattar , Jean M. Vettel , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

图像与视频处理 · 电气工程与系统科学 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland
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