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Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…

神经元与认知 · 定量生物学 2025-04-09 Laia Barjuan , Muhua Zheng , M. Ángeles Serrano

The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate. Therefore, statistical dependencies between functional signals in directly connected…

神经元与认知 · 定量生物学 2019-09-11 Maria Giulia Preti , Dimitri Van De Ville

We introduce a method that takes advantage of high-quality pretrained multimodal representations to explore fine-grained semantic networks in the human brain. Previous studies have documented evidence of functional localization in the…

人工智能 · 计算机科学 2023-06-07 Cory Efird , Alex Murphy , Joel Zylberberg , Alona Fyshe

In this work, we study the extent to which structural connectomes and topological derivative measures are unique to individual changes within human brains. To do so, we classify structural connectome pairs from two large longitudinal…

神经元与认知 · 定量生物学 2017-02-01 Dmitry Petrov , Boris Gutman , Alexander Ivanov , Joshua Faskowitz , Neda Jahanshad , Mikhail Belyaev , Paul Thompson

Integrating structural and functional connectomes remains challenging because their relationship is non-linear and organized over nested modular hierarchies. We propose a hierarchical multiscale structure-function coupling framework for…

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

神经元与认知 · 定量生物学 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

神经元与认知 · 定量生物学 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

神经元与认知 · 定量生物学 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

In recent years numerous attempts to understand the human brain were undertaken from a network point of view. A network framework takes into account the relationships between the different parts of the system and enables to examine how…

神经元与认知 · 定量生物学 2018-03-13 Nir Lahav , Baruch Ksherim , Eti Ben-Simon , Adi Maron-Katz , Reuven Cohen , Shlomo Havlin

Constructing structural brain networks using T1-weighted magnetic resonance imaging (T1-MRI) presents a significant challenge due to the lack of direct regional connectivity information. Current methods with T1-MRI rely on predefined…

计算机视觉与模式识别 · 计算机科学 2023-05-18 Yilin Leng , Wenju Cui , Chen Bai , Zheng Yanyan , Jian Zheng

Synchronization of brain activity fluctuations is believed to represent communication between spatially distant neural processes. These inter-areal functional interactions develop in the background of a complex network of axonal connections…

神经元与认知 · 定量生物学 2016-11-10 Ariel Haimovici , Pablo Balenzuela , Enzo Tagliazucchi

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

神经元与认知 · 定量生物学 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach…

神经元与认知 · 定量生物学 2018-09-14 Federico Battiston , Jeremy Guillon , Mario Chavez , Vito Latora , Fabrizio De Vico Fallani

The human structural connectome has a complex internal community organization, characterized by a high degree of overlap and related to functional and cognitive phenomena. We explored connectivity properties in connectome networks and…

无序系统与神经网络 · 物理学 2025-02-24 V. Tiselko , O. Dogonasheva , A. Myshkin , O. Valba

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

Brain imaging data mapping onto human connectome networks enables the investigation of global brain dynamics, where the brain hubs play an essential role in transferring activity between different brain parts. At this scale, the…

斑图形成与孤子 · 物理学 2025-07-11 Bosiljka Tadic , Marija Mitrovic Dankulov , Roderick Melnik